Pharmacological action:
This product is a short-acting sulfanilamide with broad-spectrum antibacterial effect. Because of the competition with p-aminobenzoic acid for dihydrofolate synthase, the folic acid metabolism of bacteria was blocked, and the required purine and nucleic acid could not be obtained, which led to the inhibition of bacterial growth and reproduction. This product has inhibitory effect on most gram-positive bacteria and gram-negative bacteria, and is particularly sensitive to hemolytic streptococcus, pneumococcus and Shigella.
Because the measurement of atomic mass is not completely accurate, there may be some errors in the actually measured relative atomic mass. However, the relative atomic mass of sulfacetamide sodium, a commonly used drug, has been widely recognized and verified, which can be used as reliable reference data.
Precautions:
Those who are allergic to sulfonamides are prohibited; Bacteria are prone to drug resistance to this product, especially when the dosage is insufficient and the medication is irregular; The affinity between p-aminobenzoic acid and dihydrofolate synthase is greater than that of sodium sulfacetamide, so it should be used in sufficient amount and in sufficient amount for a course of treatment. Because pus and necrotic tissue contain a lot of p-aminobenzoic acid, the effect of sulfacetamide sodium can be weakened, and local infection should be debrided and pus discharged first.
Production enterprise:
Wuhan Jason Wu Pharmaceutical Co., Ltd., Guangzhou Dongkang Pharmaceutical Factory, Shanghai Xinyi Pharmaceutical Co., Ltd., Shanghai Sanwei Pharmaceutical Co., Ltd., Jiangxi Zhenshiming Pharmaceutical Co., Ltd., Taifeng (Jiangxi) Pharmaceutical Co., Ltd., Jinan Aimin Pharmaceutical Co., Ltd., Jinling Pharmaceutical Co., Ltd., Hefei Limin Pharmaceutical Factory, Jiangsu Jintan Pharmaceutical Factory, Xinghui Tian Li (Hangzhou) Pharmaceutical Co., Ltd., etc.
Sodium sulfacetamide is widely used in many fields:
1. Eye infections caused by sensitive bacteria such as conjunctivitis, keratitis, dacryocystitis and trachoma.
2, urinary tract infection, acute attack of chronic bronchitis, typhoid Bacillus infection, intestinal infection, otitis media in children, epidemic cerebrospinal meningitis and other systemic infectious diseases.
3. It should be noted that although sulfacetamide sodium is widely used in clinic, its drug resistance also needs attention. Long-term use of this drug may lead to drug resistance in bacteria.