Main construction contents of the project: 10000㎡ comprehensive office building, 3000㎡ power workshop, 12000㎡ bulk drug warehouse and export preparation warehouse, 4 * * * 10000㎡ sterile bulk drug workshops and 3 * *1.
Third, environmental protection and energy conservation.
The production process of this project is mainly the process of refining, sterilization, sub-packaging and packaging of raw materials. The main auxiliary raw materials are pure water, a small amount of alcohol and activated carbon, and the main power is two 1000 KVA transformers and a small amount of steam (provided by Xingtai Ruijingkang Biotechnology Co., Ltd.). The pollution sources discharged by this project are a small amount of activated carbon (solid waste), domestic wastewater and clean and sanitary water (liquid waste is less than 50m &；; Sup3), low decibel mechanical equipment running noise, will not pollute the surrounding environment.
This project has carried out environmental evaluation and special evaluation of energy saving, which meets the relevant national standards. Greening the factory area and its surroundings according to the requirements of pharmaceutical production enterprises can not only beautify the environment, but also reduce environmental pollution.
Four. Economic and social benefits
After the project is completed and put into operation, it can produce sterile raw materials 1000 tons, oral solid preparations1000 billion tablets, 700 million water needles and 0/000 million powder needles every year, with an annual sales income of more than 400 million yuan and profits and taxes of more than 80 million yuan, which not only has considerable economic benefits, but also can earn foreign exchange through export, and can also arrange employment for more than 500 local people.
Shijiazhuang jingjing drug co., ltd
Shijiazhuang Jingjing Pharmaceutical Co., Ltd. is a pharmaceutical enterprise that produces and manages aseptic raw materials (arginine and anhydrous sodium carbonate).
The first company to transform market demand into an entity enterprise with the fastest action.
Enterprises producing cephalosporin products must rely on imported cosolvents and sterile raw materials, such as arginine and anhydrous sodium carbonate. And the high price and the return of goods after quality problems are what they urgently need to solve. In view of this, Jingjing was born.
Arginine and anhydrous sodium carbonate, the first company in China to obtain legal approval for aseptic raw materials.
The first enterprise to control the physical properties of finished products through crystallization process.
The adjustment and control of crystallization process stems from the fact that in order to meet the production process requirements of different customers, and based on the principle of convenience for customers, one processing step is reduced to ensure the final product quality of customers.
The first company to produce monofilament clean clothes.
Visible foreign bodies in the injection will lead to adverse reactions such as phlebitis and blood vessel blockage in patients during use. One of the main factors leading to the excess of visible foreign bodies is the shedding of cilia produced by the material of clean clothes, which will be effectively changed by monofilament clean clothes.
The company is located atNo. 17 Gaoying Street, Shijiazhuang City, Hebei Province, with an area of about 20,000 square meters and fixed assets of 8 million yuan. It is designed, selected, installed and managed in full accordance with the GMP requirements of sterile raw materials, and passed the GMP certification organized by the US Food and Drug Administration in February 2004.
The factory environment is beautiful, the layout of production area, auxiliary area and office area is reasonable, and the people flow and logistics channels are reasonably separated and do not interfere with each other. Main production equipment 120 sets: air purification system, purified water system, water system for injection, dry-hot sterilization cabinet, wet-hot sterilization cabinet, automatic crystallization tank for crystals, crystal filtering and drying equipment and quality analysis and testing instruments. , all adopt domestic first-class equipment.
The company has more than 30 employees/kloc-0, of which more than 50% are technical personnel such as graduate students and college graduates, and the main senior managers are senior engineers and licensed pharmacists with rich experience in pharmaceutical affairs management. All employees have been trained in GMP, professional knowledge and job operation skills. Adhering to people-oriented and scientific management, the company has established a strict production management system and a perfect quality assurance system, which has been conscientiously implemented and strictly implemented throughout the production process to ensure the implementation of drug production management and quality control.
The company's existing aseptic raw materials-arginine and anhydrous sodium carbonate are all made in China.
Xingtai ruijingkang biology science and technology co., ltd
Xingtai Ruijingkang Biotechnology Co., Ltd. is a high-tech enterprise specializing in the production and sale of amino acid series products with arginine and proline as the main products. Located in Cao Zhuang Management District, Xingtai City, Hebei Province; Covering an area of 35.25 mu, * * * has 2 employees10, 4 domestic famous experts 14, 40 employees with college education or above, 90 employees with high school education and 4 employees with senior titles. Since its establishment in 2007, the company has invested more than 30 million yuan in fixed assets, and it is estimated that the investment in fixed assets will be more than 50 million yuan, with an annual output of 650 tons of proline 1000 tons or arginine. The company has a beautiful environment and is a thriving joint-stock bioengineering high-tech enterprise.
Xingtai Ruijingkang Biotechnology Co., Ltd. has successfully developed arginine and proline. The new production line adopts the best domestic air compressor, freezer and automatic control device for fermentation; The extraction adopts domestic advanced concentration equipment and imported membrane equipment, and the product quality reaches the medical grade standard.
Arginine fermented varieties are one of the most important varieties of medicinal amino acids, which are widely used in medicine, nutrition and health care, food and other fields, and have great demand. The acid yield was 7.5% and the extraction rate was 65%. It was rated as "domestic leading and international advanced level" by the Achievement Appraisal Center of Hebei Science and Technology Department. The newly-built production line has an annual output of 650 tons of arginine, an output value of 58.5 million yuan/year, a profit of 29.25 million yuan/year, a net profit of 23.4 million yuan/year and a tax of 5.85 million yuan/year. The arginine products produced are mainly used by Shijiazhuang Jingjing Pharmaceutical to produce high value-added products such as ornithine and citrulline.
Proline has been successfully piloted, and it is the second enterprise with industrialized production capacity in China. It is mainly used for infusion and synthesis of antihypertensive drugs such as captopril and enalapril. It has been widely used in food and pharmaceutical industries, and can be easily mixed with various feeds, premixes and multi-dimensions, and can be directly used as general equipment for the production of feeds or additives. Widely used as vitamin C additive in feed, it is used for various feeds and multi-dimensional production needs, especially for the processing of fish pellet feed, and improves the efficiency of aquaculture. It is also an important raw material for amino acid infusion, and its market application prospect is very broad. It is one of new varieties of amino acids with high added value developed in recent years. The acid production level reached 7% in the pilot test, and only Guangdong Xinghu Technology Co., Ltd. produced it in China, with the acid production level of 5.0-5.5%. Sales first use the sales network formed by the company's shareholders, and then develop the company's own sales network. The company's new production line can produce 1000 tons of proline every year. The company is handling its own export business, and will realize its own export by then. It can realize gross profit of 66 million yuan/year, net profit of 52.8 million yuan/year, and tax payment10.56 million yuan/year.
Xingtai Ruijingkang Biotechnology Co., Ltd. adheres to the development strategy of relying on technology and technological innovation, and vigorously develops cooperation with universities, research institutes and large domestic pharmaceutical companies. We cooperated with University of Shanghai for Science and Technology to develop amino acid series products and completed the laboratory test of tryptophan. It is planned to develop other high value-added amino acids such as serine and cystine. We continued to cooperate with Shenyang Branch of China Academy of Sciences, and successfully developed high protein short peptide feed for aquaculture. Continue to cooperate with Tianjin Institute of Light Industry to improve the linkage technology of boiler flue gas desulfurization and sewage treatment, add new highlights to the national environmental protection industry and become a new profit growth point for the company. The company vigorously develops the talent strategy and establishes a talent training mechanism with universities to provide high-quality technical talents for the company's future development.
The second phase project of amino acid fermentation workshop under demonstration plans to invest10.5-2 billion yuan to build a production line with an annual output of 4,000 tons of proline in five years. After putting into production, it can realize an annual output value of 504 million yuan, an annual profit of 264 million yuan and tax payment of 52.8 million yuan, and finally realize listing financing and complete a qualitative leap. At present, the company has more than 700 employees, and shareholders and all employees are confident to develop the company into a star enterprise in the bio-manufacturing industry.