Introduction of protein sequence fingerprint

Protein sequence fingerprints are based on the results of multi-sequence alignment, and are constructed from a series of rather conservative sequence motifs obtained from the alignment results, which are used to characterize the characteristics of protein families. Protein fingerprint technology consists of protein chip and analytical instrument-surface enhanced laser desorption ionization time-of-flight mass spectrometry. It can record the changes of protein components in patients' serum, draw protein fingerprint mass spectrum, and show the molecular weight and content of various protein in the sample. Through this technology, it is possible for people to own their own CD-ROM in the future, record their protein fingerprints in different stages of their lives, and understand and observe their physiological changes at the molecular level, or as a comparative reference before and after treatment. Protein fingerprint and protein chip are a new generation of biochip technology after gene chip technology. Protein fingerprint technology (which has been patented by protein in China: protein fingerprint technology for biological sample analysis, patent number 03 148375.5, inventor: Xu Yang) was rated as the first technology of protein fingerprint and protein chip in the world by the international top scientific magazine Science and the authoritative medical magazine The Lancet. The biggest advantages of its patented protein fingerprinting technology are rapidity, simplicity, easy operation, low sample consumption and Qualcomm analysis. It can directly detect urine, blood, cerebrospinal fluid, synovial fluid of joint cavity, bronchial eluent, cell lysate and various secretions. , has an absolute advantage in application. In the United States, some scientists from state and municipal universities are at the forefront of science and technology and become world leaders in science and technology by applying protein's patented fingerprint technology.