The first chapter is the basic theory of hematopoiesis
Section 1 Hematopoietic Organs
First, hematopoiesis in embryonic stage.
Second, hematopoiesis after birth
Section II Hematopoietic Microenvironment
First, the bone marrow-blood barrier.
Second, the bone marrow nerve.
Three. Stromal cell
Four. Stromal cell secretory factor
Section III Origin, Growth, Development and Regulation of Hematopoietic Cells
I. Hematopoietic stem cells and hematopoietic progenitor cells
Second, the growth and development of hematopoietic cells
Third, hematopoietic regulation.
Chapter II Morphological examination of blood cells
Section 1 Normal Blood Cell Morphology
First, the law of morphological evolution of blood cells
Second, the morphological characteristics of normal blood cells
Identification of similar cells in bone marrow
Section 2 Examination of Blood Picture and Bone Marrow Picture
First, a blood test
Second, bone marrow examination
Chapter III Chemical Staining of Blood Cells
Section 1 Overview
I. Fixation
Second, the display method of cytochemistry
Thirdly, cytochemical quantification.
Fourth, the clinical application value of cytochemical staining
Section II Peroxidase Staining
First, tetramethylbenzidine method
2,3-amino -9- ethylcarbazole method
Section III Sudan Black B Staining
Section 4 Esterase Staining
A, chloroacetic acid as-d naphthol esterase staining method
Second, non-specific esterase staining
Thirdly, esterase double staining.
Section 5 Periodic Acid-Schiff Dyeing
Section 6 Neutrophil alkaline phosphatase staining
Section 7 acid phosphatase and tartrate phosphatase staining
Section 8 Bone Marrow Iron Staining
Section 9 Cytochemical Staining Results of Common Acute Leukemia
The fourth chapter introduces modern detection technology.
Section 1 in vitro culture technology of hematopoietic stem cells and progenitor cells
I. Cultural conditions and culture
Second, the cultivation of stem cells and progenitor cells.
Section II Bone Marrow Biopsy
Indications of bone marrow biopsy
Second, the commonly used bone marrow histopathological examination techniques
Clinical application of bone marrow biopsy
Section III Chromosome Examination of Blood Cells
First, the basic characteristics of chromosomes
Second, chromosome examination methods
Third, chromosome abnormality.
Fourth, the clinical significance of chromosome analysis
Section IV Apoptosis and Its Detection
First, the basic concept of apoptosis
Second, the morphological changes of apoptosis
Biochemical changes of apoptosis
Fourthly, the gene regulation of apoptosis.
Five, the common detection of apoptosis
Biological significance of apoptosis of intransitive verbs
Chapter II Erythrocyte Diseases and Their Examination
Chapter V Overview of Anemia
Section 1 The concept, classification and clinical manifestations of anemia
Abnormal erythrocyte morphology and its application in anemia diagnosis
Chapter VI Examination of Iron Metabolic Disorder Anemia
Section 1 Iron Metabolism and Its Detection
I. Iron metabolism
Second, the detection of iron metabolism
Section 2 Iron deficiency anemia
Section 3 sideroblastic anemia
Chapter VII Hematopoietic Dysfunctional Anemia
Section 1 Aplastic Anemia
Simple red cell aplastic anemia in the second quarter
Section 3 Bone Marrow Anemia
Chapter VIII DNA synthesis disorder anemia
Section 1 Vitamin B 1: Folic acid metabolism and megaloblastic formation
The second quarter megaloblastic anemia
Chapter IX Hemolytic Anemia
Section 1 Concept, classification and clinical manifestations of hemolytic anemia
The pathophysiological changes of hemolysis in the second quarter
First, the fate of hemoglobin after the destruction of red blood cells.
Second, bilirubin metabolism is abnormal.
Third, the bone marrow hematopoietic compensatory function is hyperfunction.
Four. Abnormal red blood cells and their damaged manifestations
Verb (abbreviation of verb) Other abnormal situations
Section 3 Common Inspection Methods
A, the determination of plasma free hemoglobin
Second, determination of serum haptoglobin
Third, the determination of plasma high-iron albumin
Fourthly, the Ibus test.
Section IV Experimental Differential Diagnosis of Hemolytic Anemia
First, determine the existence of hemolysis.
Second, determine the site of hemolysis.
Third, determine the causes of hemolytic anemia.
Chapter 10 Defects of Erythrocyte Membrane
Section 1 Structure and Function of Erythrocyte Membrane
The second quarter hereditary spherocytosis
The third quarter paroxysmal nocturnal hemoglobinuria
Section 4 Other Red Cell Membrane Defect Diseases
hereditary elliptocytosis
Second, hereditary oral polycythemia.
Chapter IV XI Erythrocyte Enzyme Deficiency
Summary of erythrocyte enzyme defects in section 1.
Glucose -6- phosphate dehydrogenase deficiency in the second quarter
G-6- Parkinson's disease screening test
Two. Detection of G-6- palladium activity
Section 3 pyruvate kinase deficiency
I. Overview of pyruvate kinase deficiency
Second, pyruvate kinase fluorescence spot test
Three. Detection of pyruvate kinase activity
Chapter XII Abnormality of Globin
Section 1 Overview of Globin Abnormality
The second quarter globin production disorder anemia
I. Overview of thalassemia
Second, the detection method of thalassemia
Section 3 Abnormal Hemoglobinopathy
First, sickle cell anemia
Second, unstable hemoglobin disease.
Third, other abnormal hemoglobin diseases.
Four, hemoglobin abnormal disease test method
Chapter 13 Immune hemolytic anemia
Section 1 Autoimmune Hemolytic Anemia
Section 2 Drug-induced Immune Hemolytic Anemia
Section 3 Homoimmune Hemolytic Anemia
Section IV Detection Methods of Immune Hemolytic Anemia
I. Anti-human globulin test
Second, the cold agglutinin test
Three, cold and hot hemolysis test (D-L test)
Chapter XIV Differential Diagnosis of Other Anemia and Anemia
Section 1 Proliferative Anemia
First, hemorrhagic anemia
Second, other hemolytic anemia
Secondary anemia in the second quarter
First, infectious anemia
Second, anemia caused by chronic liver disease
Third, anemia caused by chronic kidney disease.
Fourth, anemia caused by malignant tumor.
Anemia caused by endocrine diseases
Section III Differential Diagnosis of Anemia
First, the differential diagnosis of positive color anemia
Second, the differential diagnosis of large cell anemia
Third, differential diagnosis of small cell hypochromic anemia
Fourth, the differential diagnosis of hemolytic anemia
Article 3 Leukocyte diseases and their examination
Chapter 15 Leukemia
Section 1 Overview
First, the traditional classification of leukemia
Second, the incidence of leukemia.
Third, the clinical manifestations of leukemia
Four, the laboratory examination of leukemia
Section 2 Acute Leukemia
First, the classification of acute leukemia
Second, acute lymphoblastic leukemia
Three. Acute myeloid leukemia
Four, the curative effect standard of acute leukemia
Section III Chronic Leukemia
I. Chronic myeloid leukemia
Second, chronic lymphocytic leukemia.
Section 4 Special types of leukemia
First, hairy cell leukemia
Second, juvenile lymphoblastic leukemia
Three. adult t cell leukemia
Fourth, large granular lymphoblastic leukemia
V. Eosinophilic leukemia
Six, basophilic leukemia
Seven, all myeloid leukemia
Eight, acute mixed cell leukemia
Chapter 16 Myelodysplastic Syndrome
Chapter 17 Lymphoma
The first section Hodgkin's disease
Section II Non-Hodgkin's Lymphoma
Chapter 18 Plasma Cell Diseases
Section 1 Multiple myeloma
Macroglobulinemia in the second quarter
Chapter 19 Malignant histiocytosis
Chapter 20 myeloproliferative diseases
Section 1 polycythemia vera
Section 2 Primary Thrombocytosis
Section III Primary Bone Marrow Fibrosis
Section 4 Chronic Neutrophilic Leukemia
Chapter 2 1 Other Leukocyte Diseases
Section 1 Leukopenia and Granulocytosis
Leukemoid reaction in the second quarter
Section III Infectious Mononucleosis
The fourth quarter eosinophilia
Section 5 Lipid Deposition Diseases
I. Gaucher's disease
Second, Niemann-Pick disease.
Three. Sea blue histiocytosis
Section 6 Hypersplenism
Section 7 bone marrow metastatic cancer
Article 4 Hemostasis and thrombosis and its inspection
Chapter 22 Basic theory of hemostasis and thrombosis
Structure and hemostasis of the first vascular wall
Hemostatic effect of platelets in the second quarter
First, the structure of platelets
Second, platelet arachidonic acid metabolism
Third, the hemostatic function of platelets.
Section III Coagulation Mechanism
A, coagulation factors
Second, the coagulation mechanism
Section 4 Anticoagulation System
First, antithrombin
Second, protein C system.
Three. Tissue factor pathway inhibitor
Four, other physiological anticoagulant substances
Section 5 Fibrinolytic System
1. Composition and characteristics of fibrinolytic system
Second, the fibrinolytic mechanism
Section 6 Hemorheology
First, blood fluidity and viscosity.
Second, the factors affecting blood viscosity
Section 7 Thrombosis
First, the structural classification of thrombus
Second, the mechanism of thrombosis
Chapter 23 Examination of Blood Vessel Wall and Platelet
Section 1 Examination of Vascular Wall
First of all, bleeding time
Second, the determination of von Willebrand factor antigen
Section II Platelet Test
A, platelet count and mean platelet volume determination
Second, the blood clot contraction test
Third, platelet adhesion test
Fourthly, platelet aggregation test.
Verb (abbreviation of verb) Determination of plasma G- thromboglobulin and platelet factor 4 (EUSA method)
Determination of plasma thromboxane B2 and 6- keto-prostaglandin F (ELISA)
Seven, platelet surface associated antibody determination (EusA method)
Chapter 24 Coagulation Factor Test
Chapter 25 Inspection of Circulating Anticoagulant Substances
Chapter 26 Fibrinolytic System Testing
Chapter 27 Introduction of Hemorheological Test
Chapter 28 Introduction of Prethrombotic State Examination
Chapter 29 Thrombosis and Abnormal Diseases of Hemostasis
Normal reference value of laboratory examination
A contrastive study of English and Chinese words
Chinese-English index
refer to
chromatic graph