What does Saccharomyces cerevisiae vaccine mean?

Recombinant hepatitis B vaccine (Saccharomyces cerevisiae) is made by purifying hepatitis B virus surface antigen (HBsAg) expressed by recombinant Saccharomyces cerevisiae and adding aluminum hydroxide adjuvant. It is a milky white suspension, which can be layered due to precipitation, easy to shake, and does not contain any preservatives. This vaccine is suitable for 16 years old and above who are susceptible to hepatitis B and have no response to routine immunization with hepatitis B vaccine.

After vaccination, it can stimulate people who do not respond to conventional doses and procedures to produce anti-HBV immunity. Can be used for preventing hepatitis B. ..

Extended data

Valenzuela successfully expressed HBsAg in Saccharomyces cerevisiae for the first time in 1982. 1September, 1986, Merck heavy yeast hepatitis B vaccine was patented for the first time and approved by FDA. 1In July, 1989, another recombinant yeast hepatitis B vaccine from Scobicheng Company in Belgium was also patented.

In addition to Merck and SmithKline, Beijing Tiantan Bio and Shenzhen Kangtai Company, the producers of recombinant yeast hepatitis B vaccine, also produce this vaccine in large quantities. Its advantages are: yeast is a lower eukaryotic microorganism, easy to ferment and cultivate in a medium with simple nutrients, industrialized production and high expression. Most vaccines produced and marketed on a large scale in the world are prepared by this expression system.

Baidu encyclopedia-recombinant hepatitis B vaccine

Baidu Encyclopedia-Recombinant Hepatitis B Vaccine (Saccharomyces cerevisiae)