The hospital enjoys a high reputation in the domestic daily chemical industry and has great influence in the industry. He published more than 0/00 academic papers/kloc-and won nearly 0/0 national invention patents (preparation method of apocynum venetum extract and its application in cosmetics ZL 20 10/0519626.5, paeonol bletilla polysaccharide inclusion compound and its preparation process and application ZL 20). The refining process of Bletilla striata polysaccharide gum ZL 200710191991.6, etc. ) has obtained more than 30 appraisal results; The achievement of 1 1 won the provincial science and technology progress award (the second prize of commercial science and technology progress in 2009, the application research of wheat protein peptide and its derivatives in daily chemical products; The first prize of commercial scientific and technological progress in 2008, the application research of Bletilla polysaccharide in daily chemical products, etc. In recent years, the Institute of Daily Chemical of the Research Institute has carried out basic research on the application of plant extracts such as dandelion, bletilla striata, witch hazel, perilla and peony bark. Using human skin fibroblasts cultured in vitro as carrier, the growth regulation and anti-aging effects of plant active components on skin cells, as well as anti-inflammatory, itching-relieving, freckle-fading and acne-caring effects were studied. At the same time, skin irritation, allergic reaction and phototoxic reaction experiments were carried out to clarify the skin effect of plant active ingredients. At the same time, we are also committed to improving the purity and activity of plant active ingredients. On the one hand, advanced technologies such as supercritical extraction, chromatography and membrane separation are used to improve product purity. On the other hand, we use biotechnology to enzymatically modify the active extract to improve its in vitro activity, such as using glycosidase to transform ginsenoside and using biotransformation technology to improve the effective content of resveratrol. Sulfation modification technology was used to improve the biological activity of Bletilla striata polysaccharide. Taking advantage of interdisciplinary and collaborative disciplines, the institute successfully developed vitamin C ether (patent number of whitening and freckle removing agent: ZL 2007 10 130927.7). Plant anti-wrinkle agent (patent number ZL 201010146371.2); Bletilla striata mucopolysaccharide (patent number ZL 03132343x); ); Quick-acting acne removing essential oil; Hamamelis extract; Plant protein peptide; Collagen peptide powder; Cationic guar gum and other products are widely used because of its remarkable curative effect, safety and no side effects. The Research Institute is the vice-chairman of Jiangsu Daily Chemical Association, which has great influence in the field of daily chemical industry in China, and the vice-chairman of China Daily Chemical Industry Innovation Strategic Alliance. Over the past 20 years, we have cooperated with Shantou Friendship Fine Chemical Co., Ltd. for a long time, built many natural daily chemical brands such as dandelion, Lan Ruo and Ejiao, and applied for the patent of dandelion cosmetics (patent number: ZL03 132343. X), making this enterprise a high-tech enterprise in Guangdong Province. In 2007, our hospital cooperated with Shantou Kang Wang Fine Chemical Co., Ltd., and the series of "Bletilla striata" toothpaste products were deeply loved by consumers all over the country. We also applied for the patent of Bletilla striata Chinese herbal toothpaste (patent number: ZL 200810157198.9). 20 10 our hospital cooperated with Yangzhou 12th generation bioengineering co., ltd, * * jointly developed the series products of "Xiancao" loofah water, which ranked first in net sales, and * * jointly applied for the patent of treatment method for loofah bleeding (patent number: ZL 201kloc-0/065438).