The original drug of febuxostat was Teijin Pharmaceutical of Japan, which was later listed by many pharmaceutical companies all over the world. Therefore, the first choice is naturally febuxostat of Teijin Pharmaceutical. In addition, Teijin Pharmaceutical of Japan also authorized Takeda Pharmaceutical to be listed in the United States, and Ipsen Company was listed in Europe.
Allopurinol is a purine analog, which inevitably affects the activities of other enzymes involved in purine and pyridine metabolism. Therefore, in the treatment of allopurinol, it is necessary to repeat large doses to maintain a high drug level. It may bring serious or even fatal adverse reactions caused by drug accumulation. However, febuxostat is a non-purine XOR inhibitor, so it has better safety.
Febusotan tablets belong to anti-gout drugs. Its uric acid lowering effect is also strong and lasting, and it can be used to treat chronic hyperuricemia of gout.
The main component of febuxostat is febuxostat, which is an inhibitor of xanthine oxidase (XO) and is suitable for long-term treatment of hyperuricemia with gout symptoms.