Nowadays, heroin is a notorious drug, but do you know that its inventor is felix hoffman, a world-famous expert in drug synthesis? Reviewing the whole process of the invention, experiment, popularization and supplement of heroin is enlightening to our new drug research and development today.
2.1897 On August 2 1, felix hoffman, an expert in chemical synthesis of Bayer Pharmaceuticals, Germany, synthesized a substance with the chemical structure of diethylmorphine for the first time. At that time, Bayer leaders thought it was a great invention, which could be used to replace morphine and other addictive narcotic drugs. Through the preliminary pharmacological tests on fish, cats and other animals, it was found that diethylmorphine did not produce adverse reactions.
Therefore, Bayer decided to transfer the test object to people. At first, employees and their families took this preparation, and the preliminary results also proved that there were no adverse reactions causing death and addiction.
Subsequently, less than 1 year after its invention, Bayer Company rushed diethylmorphine to the market without random large-scale (medically called large sample) clinical observation, and named it "heroin", which means "heroic new invention". By 1930s, Bayer had sold tons of high-purity heroin products, including powder, syrup and suppository, to more than 20 countries around the world, including the United States.
3. Heroin brought huge financial resources to Bayer Company: 1898, the heroin sales of Bayer Company was only 45 kg, and it soared to 783 kg after 10; 1902, the profit of heroin products accounted for 5% of the total profit of Bayer's pharmaceutical department in that year. Because Bayer did not apply for a heroin patent, driven by high profits, Santos and other world-renowned pharmaceutical companies also launched similar products.
Doctors all over the world are also impressed by the efficacy of heroin, saying that it has a "magical effect" and is effective for cough, stomach cancer and depression.