Japan Institute of Life Sciences discovered a new Bacillus natto strain with excellent polysaccharide and enzyme-producing ability, and successfully cultivated it according to its own technology and obtained a patent license.
Japan Institute of Life Sciences began to sell healthy and nutritious drinks. 1In April, 1976, it expanded its business scale and opened a manufacturing plant in Kyoto. 1August, 1986, the equipment and research equipment were completely updated, and new technologies such as cosmetic matrix, animal feed and water purification began to be studied, and the enterprise developed to "contribute to society". 1992165438+10, the business scale was expanded again, which increased the manufacturing and storage space of the Kyoto factory. 1In February 1994, this enterprise signed a contract with a Korean company to provide raw materials for healthy and nutritious drinks. 1May, 1994, the Kyoto factory was expanded again, the machines were updated, and the culture room and maturation room were added. 1994 65438+In February, enterprises began to study the efficacy of Bazhang Island and carry out pesticide-free organic cultivation in Indonesia. From June 65438 to June 0995, enterprises began to study the thrombolytic enzyme "nattokinase" contained in natto. 1996 1 1 The enterprise has set up a Kyushu factory in Anqi City, Oita Prefecture. 1997 10 obtained the patent of "sesame mineral extraction". 1April, 1998, a "Bacillus natto culture and extraction technology" with high nattokinase content was established. 1998 in may, the world's first nattokinase food "NSK" began to be sold.
In the same year, enterprises also began to sell sesame minerals. 1999 February "NSK" entered the Korean market. 1999 "NSK" entered the market in Taiwan Province province in July. In August, 2000, the company extracted effective components from Indian grass, successfully crushed them and began to sell "grass powder". In May, 200 1 year, the patent of "sesame mineral extraction method" was obtained in many countries in the world. In September of 200 1 year, a new natto capsule "NSK-SD" was sold to remove the special smell of natto. In August 2002, Tokyo opened independently. In September 2002, the business was further expanded, and the principle storage room and packaging room of Kyushu factory were added. In February 2003, the company signed an exclusive distribution agreement with the United States for "NSK-SD". In June, 2003, the powdery plant fermented extract was successfully developed and put on the market. In June 2004, 5438+ 10, the technology of culture and extraction of Bacillus natto and the technology of plant fermentation and extraction obtained international certification. (ISO 900 1:2000) In June, 2005, 10, Tokyo Branch obtained ISO 9001:2000 extended certification. In June 2005, the research system was strengthened and a new research institute was established in Kyushu factory. In March, 2006, the related technology of Bacillus natto culture "inhibiting platelet aggregation function" was obtained in the United States, and it was certified as a health food in the United States (US 7,065,438+02,8565,438+0). In July 2006, we obtained the patent of "natto culture liquid food" (patent authorization number 3834048). In June 2006, we obtained the patent of "Bacillus natto culture extract" (patent number 3881494). In February 2007, we obtained the patent of "recovery method of vitamin K2". 3911282). In July 2007, we obtained the patent of "antibacterial agent" related to Aconitum (patent number 3958748).