Popular characteristics
Sick dogs and foxes are the sources of infection of this disease and are transmitted through the respiratory tract. It only infects dogs and foxes of all ages, and is common in puppies and young foxes, especially newly weaned puppies and fox puppies. The disease can cause litter-wide morbidity of puppies under 4 months old, with high mortality. Dogs infected with this disease can carry the virus for a long time and can occur in any season. Once this disease occurs in a group, it is difficult to eradicate.
Clinical symptoms
Sick dogs showed fever, persistent dry cough, shortness of breath, loss of appetite, muscle tremors, and visible mucosal cyanosis. In some cases, vomiting and diarrhea occurred, and most of them died of pneumonia. .
Pathological changes
The main pathological changes are pneumonia and bronchitis, incomplete lung expansion, congestion, and consolidation. Sometimes hyperplastic adenoma lesions can be seen, and bronchial lymph node congestion and hemorrhage.
Differential diagnosis
1. Canine adenovirus type II infection and canine infectious hepatitis
Both of them have elevated body temperature, anorexia, depression, and diarrhea. and other clinical symptoms.
Difference: Canine infectious hepatitis has a high fever, showing an obvious biphasic fever type. Some sick dogs in the recovery period may have one-time corneal opacity, forming a blue-white corneal pannus, commonly known as "blue eye disease" . Necropsy revealed liver enlargement, thymus edema, gray-white necrotic lesions in the kidney cortex, and bleeding in the gastric serosa, subcutaneous tissue, lymph nodes, thymus, and liver.
2. Canine adenovirus type II infection and canine distemper
Both have clinical symptoms such as anorexia, depression, and diarrhea.
Difference: Canine distemper cases are more common in puppies aged 2-4 months, and sick dogs have obvious mental symptoms. An autopsy showed congestion and bleeding in the gastrointestinal mucosa, bleeding in the liver, heart, spleen, and kidneys, and congestion and effusion in the meninges.
3. Canine adenovirus type II infection and canine parvovirus infection
Both of them have clinical symptoms such as elevated body temperature, anorexia, depression, vomiting, and diarrhea.
Difference: Cases of canine parvovirus infection present with sudden vomiting, diarrhea, fishy feces, blood in the later stage, and persistent vomiting. Autopsy showed small intestinal mucosal bleeding, mesenteric lymph node enlargement, congestion, bleeding, dark red color; non-suppurative necrosis of myocardium or endocardium.
4. Canine adenovirus type II infection and canine salmonellosis
Both of them have clinical symptoms such as elevated body temperature, difficulty breathing, anorexia, depression, vomiting, diarrhea and other clinical symptoms.
Differences: Canine salmonellosis cases include severe vomiting and diarrhea; large-scale edema of the gastrointestinal mucosa, necrosis of some intestinal segments, ulcers in the upper duodenum, enlargement and bleeding of mesenteric lymph nodes; enlarged spleen, superficial There are bleeding spots (spots) and gray necrotic lesions; cardiac epicarditis and myocarditis with serous or fibrinous exudates.
5. Canine adenovirus type II infection and canine leptospirosis
Both of them have clinical symptoms such as depression, anorexia, vomiting, and elevated body temperature.
Difference: Cases of canine leptospirosis can show obvious mucosal jaundice, bloody stools, hematuria (urine is soybean oil-like), and painful muscle reactions.
Tips
A preliminary diagnosis can be made based on epidemic characteristics, clinical symptoms, and pathological changes. Further diagnosis must rely on virus isolation and serological examination (serum neutralization test and hemagglutination test). inhibition test).
Preventive and control measures
(1) Prevention
① Strengthen feeding management and regular disinfection to prevent the spread of the virus from person to person. Once the disease occurs, the sick dog should be isolated promptly and symptomatic treatment should be implemented.
②Use attenuated vaccine or mixed vaccine to achieve good results after regular immunization. Pet dogs must have planned immunization for both female dogs and puppies at the same time. After the dog recovers, the body will be immune for life.
③Emergency prevention can use homotypic or heterotypic bivalent or trivalent immune serum or immune gamma globulin, but the protection period is limited to 2 weeks.
(2) Treatment
The treatment principles are antiviral, prevention of secondary infection, symptomatic treatment and supportive therapy.
①Antiviral
Ribavirin, 5-7 mg/kg body weight for dogs, subcutaneous or intramuscular injection, once a day;
Interference For dogs, 100,000-200,000 units/time should be injected subcutaneously or intramuscularly, once every 2 days.
② Antibacterial
Ampicillin, 20-30 mg/kg body weight for dogs, orally, 2-3 times a day, or 10-20 mg/kg body weight, subcutaneously or intramuscularly Intramuscular injection or intravenous infusion, 2-3 times a day;
Cefazolin sodium, 1-3 mg/kg body weight for dogs, intramuscular injection or intravenous infusion, 3-4 times a day;< /p>
Sunuo (Amoxicillin and Clavulanate Potassium Suspension), for dogs and cats, 0.1 ml/kg body weight, subcutaneous or intramuscular injection, once a day;
Fufangxin Nomin, 15 mg/kg body weight for dogs, orally or subcutaneously, twice a day.
③Antitussive and phlegm-reducing
Potassium iodide, 0.2-1 g/time, orally, 3 times a day;
Pentoverine, for dogs 2 mg/time, orally, 2-3 times a day.
④Fluid rehydration
Adenosine triphosphate (ATP), coenzyme A, vitamin C, 50% glucose saline, 5% glucose, etc.