From 1994 to 1997, he was engaged in the research of X(?)-ray stereotactic radiotherapy technology, and was mainly involved in the research and development of OUR company’s X-knife and CREAT company’s X-knife. In cooperation with Professor Hu Yimin, he proposed for the first time in the world the method of repositioning embedded gold markers to carry out stereotactic radiotherapy of the body.
Since 1999, he has been engaged in research on optimal design methods of radiotherapy plans and implementation technology of intensity-modulated radiotherapy, and proposed the technology of using independent collimators to carry out intensity-modulated radiotherapy. This is the only technology proposed by Chinese scientists. Intensity-modulated radiotherapy implementation technology; establishing a variety of algorithms for optimizing field parameters and algorithms for generating intensity-modulated subfield sequences, such as algorithms for optimizing conformal radiotherapy field weights and wedge-shaped plates based on the concept of super-omnidirectional wedge plates, and optimizing the direction of irradiation fields mixed integer linear programming model.
Since 2001, we have carried out research on the clinical application of intensity-modulated radiotherapy, established a complete workflow for intensity-modulated radiotherapy plan design, dose verification and treatment implementation, independently developed an independent radiation dose verification program, designed and produced A variety of intensity-modulated radiotherapy verification phantoms were developed, and the dose verification results of a large sample of patients were reported for the first time in China. The technical specifications we established have been rapidly promoted and applied across the country through the publication of papers, academic reports, and visits to the institute for further study, resulting in huge economic and social benefits.
Has published 32 papers in Medical Physics and Physics in Medicine and Biology or domestic core journals representing the highest level in the field of international medical physics, including 13 papers with SCI impact factors greater than 2, and is the first author of the paper 16 articles; due to his important contribution in the research and development of the X-ray knife system, as the main completion person, he won the second prize of the Guangdong Province Science and Technology Progress Award; he won the academic paper award of the cancer hospital many times; he applied for one Chinese patent and one US patent each.