Glenin, whose real name is Gleevec, mentioned in the film Dying, is a first-line anticancer drug developed by Novartis, with an effective rate of 95%. Gleevec's great success in treating CML and GIST has attracted great attention from medical and scientific circles. However, just like in movies, its price is expensive in reality. It is said that the price of each box in China is nearly 20 thousand, and each box can only be eaten for one month. The price of Indian generic drugs is around 200 yuan per box. For ordinary families, Indian generic drugs are life-saving drugs.
Among the people, there are: can't afford to be born, can't afford to be sick, and can't afford to die. Nowadays, it is not uncommon to spend one or two thousand yuan on a cold. If you are unfortunately seriously ill, it will bring heavy economic pressure to ordinary families. Just like in the movie "Die to Live", those patients, faced with expensive drugs, are at a loss and can only wait for death. But there are many viewers who have the same questions as me. In the film, China has 4 1000 bottles of medicine, while the Indian-made medicine with the same effect only needs 2000 yuan, and the purchase price only needs Wu Bai dollars. Why are Indian medicines so much cheaper than those in China? Perhaps many people don't know that India is known as the "world pharmaceutical factory".
There is a prototype of "the first person in India to purchase anticancer drugs". This film tells the story of Yong Cheng, played by Xu zhēng, who was forced by family pressure to get rich at first, and began to illegally buy Indian "fake medicine" for treating chronic myeloid leukemia, but he quit after earning the difference. However, when he saw that his former friend was tortured by illness and eventually passed away, and that many patients were unable to pay for genuine drugs and lamented the pain, he once again embarked on the road of selling fake drugs. Only this time, he abandoned material interests and only sold drugs at the cost price to save the lives of the sick groups. The film is adapted from a true story. The prototype of the film is Lu Yong, who is known as "the first Indian to purchase anticancer drugs". His story is based on Gleevec's generic drug.
As we all know, drugs are life-saving and can't tolerate any mistakes, so a lot of work needs to be done before a new drug goes on the market. Since it is research and development, we must first make a good research plan, that is, we must know what to study and how to study it. Therefore, at this stage, it is necessary to analyze the market and industry trends, find a lot of literature, and even prepare new compounds in the laboratory, but this is only the beginning. Then the preclinical research of new drugs, including synthesis technology, dosage form selection, inspection methods, quality standards, stability, pharmacology, toxicology, animal pharmacokinetics and so on. These things are incomprehensible to laymen and exhausted to experts.
Then enter the clinical research stage of drugs. The clinical study of new drugs is divided into four phases, namely, phase I, phase II, phase III and phase IV, which will not be conducted. In short, you only need to know that the clinic is in the patient's bed, that is, at this stage, the medicine has been tried on the patient. I still remember that some time ago, one of our customers, a Canadian pharmaceutical company, suffered a phase III clinical failure, which caused its share price to plummet in one day! Watch the red circle. I have been talking about the process of new drug research and development for so long. In fact, what I want to tell you is that the investment in research and development of a new drug is huge. It is normal to spend hundreds of millions or even billions in a short period of time, and these efforts may not necessarily lead to the final success of research and development.
Indian pharmaceutical companies simplify or even omit these processes, which is equivalent to reducing the cost by at least hundreds of millions of dollars, so people will not lose money even if they sell cheap specific drugs.
India's generic drugs, such as Granin India in the film, are cheap and good, which are not only the lifeline of patients in developing countries, but also the lifeline of patients in some developed countries, and even go to India for medical treatment or treatment. For example, in India, about 550 laboratories supply drugs to the lucrative American market, and they also occupy 90% market share.
It is precisely because generic drugs do not have this cost that the drug price will be much lower than the genuine ones. Of course, some people may say, why can't China have a dual-track patent system like Indian? In fact, if it is really done, it will be a heavy blow to the enterprises that have worked hard to study new drugs. In this case, pharmaceutical companies will have no incentive to develop new drugs.