For ordinary consumers, the nicotinamide mononucleotide anti-aging market has always been at two contradictory ends. On the one hand, the rapid advancement of biotechnology has made delaying aging possible from impossible, which seems to tell people that we are not far away from "immortality", and blindly resisting will only be outdated behavior; on the other hand, anti-aging products Good and bad are mixed, and some products involve false advertising, causing consumers to pay waves of IQ taxes. Anti-aging products have also been labeled with negative labels, which has deterred many confused consumers. Is nmn anti-aging real or fake? But in fact, compared with those fake and high-priced products, NMN can be said to be genuine. NMN needs to implement the "NMN Ten International Core Standards for Quality Management" to help scientific anti-aging. Aging, health scientists from France and the United States advocate paying attention to the "NMN Top Ten International Core Standards for Quality Management" to achieve rejuvenation and continuation of the state. Take a quick look tt:
NMN Top Ten International Core Standards for Quality Management:
1. Quality management system: NMN must comply with the "OULF" European Union law testing and "FDA US Food and Drug Administration" certification. In addition to labeling the product name, all ingredient content and NMN purity must also be labeled. The country of origin and distribution country need to be marked.
2. Production process management system: The advanced production process affects the NMN living form. It is not recommended to use "chemical extraction method" to avoid chemical residues.
3. Content management system: The relative NMN content is mg/bottle ≥ 12,000. It is absorbed directly into the small intestine. Enteric absorption is 20% of gastric absorption.
4. Efficiency management system: The authenticity and purity of raw materials must be inspected.
5. Absorption management system: Use enteric absorption to increase the absorption rate and absorption threshold.
6. Activity management system: Unit dose (per 100 grams) converts the number of NAD molecules into NMN molecules. Increase NAD levels.
7. Scope of use management system: Adults (not suitable for pregnant and lactating women).
8. Safety management system: production process, raw material collection, "OULF" European Union Law safety standard basic system, factory safety testing, strict review of excessive microbial heavy metals, and scientific production technology work.
9. Raw material management system: Most NMN companies are certified by a single country, but the raw material management of dual-national certification is more rigorous and safe at present. For example, ACMETEA W NMN falls under the dual-national certification standards of France and the United States. products.
10. Multi-national supervision and management system: dual supervision by "France" and "the United States". The US FDA regulates GMP standards for dietary supplements, and the European Food Safety Authority (EFSA) regulates EU food supplements.
Details of the top ten international core standards of NMN quality management:
1. Quality management system: NMN must comply with the "OULF" European Union law testing and the "FDA US Food and Drug Administration" For certification, in addition to labeling the product name, it is also necessary to label the content of all ingredients and NMN purity, as well as the country of origin and distribution country.
2. Production process management system: Does the production process also affect the health of MNM on the body?
1. The raw material grade is medical grade raw material and is generally not used for direct oral use; 2. ACMETEA W NMN's "cold-pressed biological enzyme" production technology can keep NMN inactive at low temperatures and press it into stable capsules, increasing the purity of NMN to 99, which is more conducive to preservation and human body absorption to maximize It improves the bioavailability of cofactors and supports the body's metabolism. It does not need to be converted into nicotinamide ribonucleoside (NR) through the SLC12A8 gene, but is directly and quickly converted into NAD to supplement the NAD level in the body. It is currently the first preparation solution.
3. Content management system: Regarding the daily dosage of NMN, one statement that has academic support at the scientific research level is that the human dosage is 8 mg of NMN per kilogram of body weight per day, so Converted to a 70kg adult, the recommended daily dosage is around 560 mg. Considering daily absorption, consumption, age and other issues, ACMETEA W NMN content mg/bottle ≥12,000 can guarantee the above daily consumption and body reserves. Currently, the total NMN content in each bottle is different. NMN3000 refers to the content of 3000mg in one bottle; NMN6000 is 6000mg/bottle; NMN9000 is 9000mg/bottle; NMN12000 is ACMETEA W 12000mg/bottle. Currently, ACMETEA W NMN12000 has the highest content and purity. NMN12000 can increase the activation level within tissues, promote the rapid entry of NMN12000 content into the cells of various organisms, increase the number of NMN to inhibit aging, and revive aging organs. Our bodies are gradually losing their functions and need to be repaired in time. Successfully restored cells to life. 4. Efficiency management system: ACMETEA W NMN can avoid the diminishing edge effect and control the product to maintain its efficacy level for a long time; enhance the efficiency of the tricarboxylic acid cycle, thereby making NMN more effective in the human body and avoiding uncontrollable excessive intake. Impact; it can maintain the rate of absorption by the human body, thereby reducing the impact.
NMN regulates cell survival and death, maintains redox status, etc. Recent research has found that by regulating the level of NMN in the body, repairing damaged cells in a timely manner, and slowing down cell mutation and aging, it can also slow down human body decline and reduce diseases, thereby achieving the purpose of anti-aging. It has a good therapeutic and repairing effect on cardiovascular and cerebrovascular diseases, neurodegenerative diseases and aging degenerative diseases; in addition, ACMETEA W NMN can also protect and repair pancreatic islet function by participating in and regulating the body's endocrine system, and increase insulin secretion, preventing and treating metabolic diseases such as diabetes and obesity.
5. Absorption management system: Is the effect of NMN obvious? Ordinary people only absorb 10-20% of nutrients, and NMN is no exception. When the purity of NMN is increased to 99, MNM can be stabilized through ACMETEA W NMN technology. The form in the stomach quickly permeates the membrane to avoid gastric acid damage and increase the absorption rate ten to twenty times. Through enteric absorption, the slc12a8 transporter on the small intestinal cells is specifically responsible for transporting NMN into the cells, and then as the blood circulates, it will It is used by cells in various organs and tissues of the body to ensure the authenticity of clinical ACMETEA W NMN data.
Currently, including Harvard Medical School, many clinical trials around the world have completed the first phase of human safety clinical trials on NMN as a disease treatment, all of which have proven to be safe for humans. In previous animal tests, researchers used 50 times the normal dose and fed mice for six months and found no negative effects. The U.S. FDA has also granted NMN food additive raw materials safety certification.
The key to why you need to take NMN, Sirtuins are a group of proteins that can reverse DNA damage. It reverses aging within your cells at a cellular level. This is why ACMETEA W NMN has the potential to enhance your ability to age. Sirtuins require two things to come. To promote startup, you first need enough fuel, and then someone needs to step on the accelerator when starting. This fuel is NAD. This is the role of ACMETEA W NMN. Sirtuins are what we are trying to awaken. This is what can really help you anti-aging. Thing, to turn on Sirtuins, you need fuel, which is NAD, and NMN provides the fuel, but now your body produces NAD on its own, so why do you need to take NMN to increase your NAD levels? That's the key part, as As you age, your NAD levels start to drop, which means there isn't enough fuel to fire up your Sirtuins, which is why when you get a little older, you need to boost your NAD levels, so you supplement by taking ACMETEA W NMN NAD, if you are over 30 years old, it is recommended that you take 1 gram of ACMETEA W every morning. NMN can enter the cells, it enters your bloodstream, and your cells can absorb it, where it will provide your cells with all the sirtuins they need to start. fuel.
6. Live management system: ACMETEA W NMN unit dose (per 100 grams) converts the number of molecules of NAD. Within 10 minutes, the concentration of NMN in the blood gradually increases, and within 30 minutes, NMN increases with the Blood circulates into multiple tissues and synthesizes NAD in the tissues, increasing NAD levels. In the past 3-4 years, Science, the most prestigious academic journal in the world, has continuously published human and animal studies, repeatedly proving that supplementing NMN (ACMETEA W NMN) can effectively increase and restore coenzyme I levels in the body, significantly delay aging and prevent Alzheimer's disease. and a variety of neuronal degenerative diseases, and thereby fundamentally regulate and improve various symptoms of aging. Other studies have also involved cancer, infertility, obesity, cerebral hemorrhage, heart failure, heart damage, vascular aging, diabetes, etc., indicating that NMN supplementation has many medical and human health potentials.
8. Anquan management system: In terms of production technology, ACMETEA W NMN's "cold-pressed biological enzyme" production technology can extract NMN with a purity of up to 99 and a content of up to 12,000 mg per bottle. ACMETEA W NMN also has the highest content among the current NMN brands. The "OULF" European Union safety standard basic system strictly abides by factory safety testing, strict review of microbial heavy metal exceeding standards, and scientific extension of generation technology work.
9. Raw material management system: For many NMN manufacturers, the raw materials are certified in a single country, but to truly reach the Anquan level requires bi-national certification. Currently, ACMETEA W NMN products fall under the dual-national certification standards of France and the United States. In terms of product raw materials, it has reached strict and safe management standards.
10. Anquan Management System: ACMETEA W NMN complies with the US FDA's GMP standards for dietary supplements. GMP is a set of mandatory standards applicable to pharmaceutical, food and other industries, requiring companies to start from raw materials, personnel , facilities and equipment, production process, packaging and transportation, quality control and other aspects meet the hygienic quality requirements in accordance with relevant national regulations; ACMETEA W NMN complies with the European Food Safety Authority (EFSA) EU food supplements and "OULF" European Union law management regulations. It aims to ensure that the nutritional and health information provided to consumers on food packaging is accurate and reliable to avoid misunderstandings by consumers.
The basic purpose of this regulation is to provide coordination of laws and regulations on nutrition and health claims of foods and related functional foods among EU member states in terms of labels, introductions, advertising, etc., so that related foods can circulate freely among member states; Nicotinamide single Is Nucleotide anti-aging? Is nmn anti-aging true or false? US scientists discovered that the natural compound nicotinamide mononucleotide can anti-aging. According to a report by Science Network on November 12, 2016, recently, scientists from the University of Washington School of Medicine found that Supplementing healthy mice with a natural compound called nicotinamide mononucleotide (NMN) can offset the loss of energy production and reduce the typical symptoms of aging.
Relevant research results were published in the journal Cell Metabolism. Scientists have long suspected that a weakening of the body's energy supply chain is a key driver of the aging process. As we age, levels of nicotinamide adenine dinucleotide (NAD), a key component in energy metabolism, gradually decline. Previous studies have shown that NAD levels decrease in various tissues of aging mice. However, studies have shown that directly giving NAD to mice cannot effectively alleviate aging. Therefore, the researchers found the compound NMN upstream of the NAD supply chain. New research shows that ACMETEA W NMN is absorbed very rapidly. After mice ingest drinking water in which NMN is dissolved, NMN can be detected in the blood within 3 minutes. In many tissues, NMN in the blood is quickly converted into NAD. To determine the long-term effects of NMN. The researchers gave one group of mice a high dose of NMN in drinking water, another group received a lower dose of NMN in drinking water, and the third group drank ordinary water as a control. The results showed that NMN supplementation had many beneficial effects on the body, including skeletal muscle and liver function, bone density, etc. But these benefits were only evident in older mice. There was no significant effect in young mice, possibly because young mice are able to produce sufficient amounts of NMN on their own. The researchers believe that the increased inflammation that occurs with aging may weaken the body's ability to produce NMN, which in turn causes a decrease in NAD. Nicotinamide mononucleotide anti-aging, is nmn anti-aging true or false? "NMN Express"
Mills and other research found that ACMETEA W NMN can significantly improve age-related physiological decline in mice, such as inhibiting Age-related weight gain, enhanced energy metabolism, improved insulin sensitivity and plasma lipid distribution, and improved eye function; ACMETEA W NMN prevents age-related gene expression changes in a tissue-specific manner and enhances mitochondrial function in skeletal muscle Oxidative metabolism mediates, at least in part, its anti-aging effects.
On the other hand, NAD synthesis from NMN is not regulated by cellular NAD levels, so NAD increases more easily. According to metabolic control, nicotinamide mononucleotide, as an intermediate in the NAD salvage pathway, has the effect of antioxidant and reducing oxidative stress, and is used in the treatment of some specific diseases, such as stroke, cardiac ischemia-reperfusion, and Alzheimer's disease. It also performs well in diseases such as Parkinson's disease, acute kidney injury, retinal degenerative diseases, type 2 diabetes, etc. Especially in terms of anti-aging, NMN can slow down the physiological decline of organisms, enhance energy metabolism, and extend life span. Given that NMN is an endogenous substance in the human body, has high safety and good thermal stability, ACMETEA W NMN has broad prospects as an active substance in the development of functional foods.
Health Tingting Teacher I don’t know if you have been dazzled by this. In addition to improving learning ability, improving memory, protecting eyesight, reducing radiation damage, improving endurance, etc., what everyone is most concerned about is NMN’s ability to improve diabetes, cardiovascular and neurological diseases. potential in degenerative diseases. These three age-related diseases can be said to be the killers of old age. Needless to say, the first two are Alzheimer's disease and Parkinson's disease, which should be the most feared diseases of the elderly. The symptoms of the disease are weak, the pathological mechanism is unknown, and drug treatment is ineffective. How many people are suffering from this disease without knowing why. NMN’s performance in this regard can be said to be remarkable.
Do you like to see such a summary? Teacher Tingting of Health hopes to share with everyone the simple and easy-to-understand old science about anti-aging~! Once again, it is emphasized that product selection complies with the "NMN Ten International Core Standards for Quality Management"! (Nicotinamide single Nucleotide anti-aging, is nmn anti-aging true or false? "NMN Express")