Because of its bactericidal effect, taking methylene blue orally or washing with its solution can treat cystitis and urethritis. In addition, methylene blue will be excreted from the urine within 30 minutes (injection) to several hours (oral administration) after entering the human body, resulting in the urine being temporarily blue, so it is also used for renal function measurement. In the cultivation of ornamental fish, 0. 1-0.2ppm methylene blue solution is also used to disinfect or treat diseases such as white spot disease.
Extended data:
Hazard description:
Oral-rat LD50:1180mg/kg; Oral LD50 of mice: 3500mg/kg.
High concentration methylene blue solution oxidizes hemoglobin to produce methemoglobin. The reason is that the product enters the body in large quantities, and the production of reduced coenzyme I dehydrogenase (NADPH) is reduced, so that it cannot be completely converted into reduced methylene blue, and the amount of oxidized methylene blue is large, and hemoglobin is oxidized into methemoglobin. ?
Intravenous injection of methylene blue solution, when the dose is too large (500mg), can cause nausea, abdominal pain, precordial pain, dizziness, headache, sweating and unconsciousness and other adverse reactions.
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