Diagnosis and treatment of epileptic encephalopathy;
After fully evaluating the brain structure and function (high-resolution MRI, PET neuropsychological examination), on the basis of fully screening the etiology at the level of genetics and molecular biology, patients with epileptic encephalopathy were treated with neurosurgery, dietotherapy and drug therapy.
Surgical treatment of epilepsy;
For patients with drug-resistant epilepsy who are suitable for surgical treatment, the department provides scientific and comprehensive surgical treatment. In recent years, in addition to the conventional resection of epileptic foci in frontal lobe, temporal lobe, parietal lobe and occipital lobe, hemispheric/multi-lobectomy and hemispheric/multi-lobectomy, the resection of epileptic foci in insular lobe, central area and language functional area, functional area awakening anesthesia resection and SEEG-guided thermocoagulation surgery have been carried out to treat small deep lesions. For partial multifocal or generalized epilepsy, total corpus callosum resection, vagus nerve stimulator implantation (VNS) and deep brain stimulation (DBS) were performed.
Surgery is the first in China to place subdural electrodes in craniotomy to accurately locate epileptic foci. In 20 16, the French ROSA surgical robot was introduced, and by 20 19, more than 100 cases of SEEG were implanted, and the total number of electrodes exceeded 1200.
Ketogenic diet therapy:
Ketogenic diet therapy (KDTs) is a recognized non-drug therapy for intractable epilepsy in children and adults. Since 192 1 year, the classic ketogenic diet therapy has been often used to treat epilepsy. Shanghai Deji Hospital set up a ketogenic diet treatment unit at the beginning of its establishment, and by 20 19, nearly 3,000 patients with intractable epilepsy have been treated.