For the compound, it is not necessary to disclose the synthetic method in the patent, but in the specification, it is necessary to explain the novelty and creativity of the compound in detail, that is to say, sufficient evidence must be provided to prove that the compound is indeed a new compound, and examples of its use must be provided. If the examiner has reason to think that the compound is not novel, the application will be rejected, for example, the compound has been mentioned in any prior art, so the compound must not be novel.
In addition, in order to protect the synthetic method, under normal circumstances, the patent of the compound, its preparation method and use are applied together, otherwise, after the compound is published, others can still apply for the patent of the synthetic method of the compound.