1. There are several kinds of capsule skins, one is gelatin capsule skin and the other is starch capsule skin;
1, gelatin capsule skin: mainly made of animal leather. Poisoned capsules occurred in 12 years, so be cautious when purchasing;
2. Starch capsule skin: The capsule skin mainly made of plant starch is much safer than gelatin capsule skin, but you still need to be careful when purchasing, so as not to be deceived. It's best to choose a bigger brand.
Second, the main characteristics of starch capsule skin
(1) 100% natural cassava starch.
Starch capsules are made of 100% natural cassava starch and proper amount of purified water through a special process, and do not contain any chemical additives and preservatives.
(2) No animal-borne infectious diseases.
No animal-derived substances and animal protein are added in the production, which completely eliminates the potential safety hazards caused by mad cow disease and poison capsules.
(3) Non-transgenic
The starch used in the production does not use genetically modified varieties, and the raw materials are strictly controlled, and it has passed the international SGS non-genetically modified certification.
(4) No pesticide residue
Cassava, the raw material used in the production, is imported from Cambodia, and no pesticides are used in the organic planting process. At the same time, advanced technology is adopted in the production process to further ensure that the products are free of pesticide residues.
(5) No carcinogen residue.
Strictly control the production conditions, never use ethylene oxide to sterilize the products, and there will be no carcinogen residue.
(6) Take care of the stomach
Taking powder directly is easy to burn esophagus and gastric mucosa and cause ulcer. Some powders are too big, which are easy to choke into trachea and corrode trachea mucosa. Using empty starch capsules as carriers can protect the stomach and intestines well.
(7) no cross-linking reaction with drugs
Starch is a substance with stable molecular structure, which will not cross-link with aldehyde groups or other compounds to prevent internal substances from deteriorating and cross-linking due to capsules.
(8) The drug utilization rate and absorption effect are good.
The effective components in starch are more helpful to stimulate the activity of powder, which is beneficial to human absorption and increase the use efficiency of precious Chinese herbal medicines.
(9) It is easy to be accepted by people of special culture.
The raw material of empty starch capsules is pure starch, which is more in line with the eating habits of people with special religious beliefs and vegetarians. Products have passed the European Vegetarian Association certification, * * * certification and kosher certification.
(10) Easy to store and carry.
Starch hollow capsules have low requirements on temperature and humidity, and can be stored and carried under normal conditions.
Third, the delivery process.
BC 1500, the first empty capsule was born in Egypt;
1846, two-stage hard capsule manufacturing technology was patented in France;
1874, Detroit began the industrial manufacture of hard capsules, and introduced various models at the same time;
193 1 year, large-scale production of empty capsules began, accounting for 70% of all kinds of drugs;
During the period of 1986, the outbreak of mad cow disease from Britain to Europe made gelatin capsules fall into an unprecedented crisis of confidence, and people began to look for plant materials to replace gelatin.
During the period of 1997, Pfizer introduced two kinds of plant hollow capsules. Hollow capsules made of hydroxypropyl cellulose-not conducive to human digestion, but made of pullulan-are extremely expensive and complicated. Experts in the industry agree that starch, as three essential nutrients for human beings, is the best raw material for producing plant hollow capsules.
In 2000, hollow starch capsules were formed, but due to the technical problems of starch fluidity, formability and properties, it has been impossible to realize industrial production.
In 2004, Hunan Erkang Pharmaceutical Co., Ltd. started the research and development project of starch capsules;
In 20 13, Erkang Pharmaceutical, together with senior scholars from Australia and Canada, took the lead in overcoming a number of core technical difficulties and realized the industrialization of empty starch capsules.
In 20 14, the world's first empty starch capsule industrial park was built in Liuyang Biomedical Park.
In 20 15, erkang starch hollow capsules will be fully sold and become the largest professional supplier of starch hollow capsules in the world.
Fourthly, compared with gelatin (the terminator of poison capsules)
20 12 April 15 CCTV Weekly Quality Report and Oriental Time and Space Report, some gelatin production enterprises used quicklime to decolorize and bleach leather scraps, and then boiled them into industrial gelatin and sold them to Zhejiang Xinchang Medicine.
Capsule manufacturers eventually flow to pharmaceutical companies. Through investigation, it was found that the content of heavy metal chromium in capsules used in 9 pharmaceutical factories 13 batches of drugs exceeded the standard, of which the most exceeded the standard. ......
What is the composition of capsule skin?
1. There are several kinds of capsule skins, one is gelatin capsule skin and the other is starch capsule skin;
1, gelatin capsule skin: mainly made of animal leather. Poisoned capsules occurred in 12 years, so be cautious when purchasing;
2. Starch capsule skin: The capsule skin mainly made of plant starch is much safer than gelatin capsule skin, but you still need to be careful when purchasing, so as not to be deceived. It's best to choose a bigger brand.
Second, the main characteristics of starch capsule skin
(1) 100% natural cassava starch.
Starch capsules are made of 100% natural cassava starch and proper amount of purified water through a special process, and do not contain any chemical additives and preservatives.
(2) No animal-borne infectious diseases.
No animal-derived substances and animal protein are added in the production, which completely eliminates the potential safety hazards caused by mad cow disease and poison capsules.
(3) Non-transgenic
The starch used in the production does not use genetically modified varieties, and the raw materials are strictly controlled, and it has passed the international SGS non-genetically modified certification.
(4) No pesticide residue
Cassava, the raw material used in the production, is imported from Cambodia, and no pesticides are used in the organic planting process. At the same time, advanced technology is adopted in the production process to further ensure that the products are free of pesticide residues.
(5) No carcinogen residue.
Strictly control the production conditions, never use ethylene oxide to sterilize the products, and there will be no carcinogen residue.
(6) Take care of the stomach
Taking powder directly is easy to burn esophagus and gastric mucosa and cause ulcer. Some powders are too big, which are easy to choke into trachea and corrode trachea mucosa. Using empty starch capsules as carriers can protect the stomach and intestines well.
(7) no cross-linking reaction with drugs
Starch is a substance with stable molecular structure, which will not cross-link with aldehyde groups or other compounds to prevent internal substances from deteriorating and cross-linking due to capsules.
(8) The drug utilization rate and absorption effect are good.
The effective components in starch are more helpful to stimulate the activity of powder, which is beneficial to human absorption and increase the use efficiency of precious Chinese herbal medicines.
(9) It is easy to be accepted by people of special culture.
The raw material of empty starch capsules is pure starch, which is more in line with the eating habits of people with special religious beliefs and vegetarians. Products have passed the European Vegetarian Association certification, * * * certification and kosher certification.
(10) Easy to store and carry.
Starch hollow capsules have low requirements on temperature and humidity, and can be stored and carried under normal conditions.
Third, the delivery process.
BC 1500, the first empty capsule was born in Egypt;
1846, two-stage hard capsule manufacturing technology was patented in France;
1874, Detroit began the industrial manufacture of hard capsules, and introduced various models at the same time;
193 1 year, large-scale production of empty capsules began, accounting for 70% of all kinds of drugs;
During the period of 1986, the outbreak of mad cow disease from Britain to Europe made gelatin capsules fall into an unprecedented crisis of confidence, and people began to look for plant materials to replace gelatin.
During the period of 1997, Pfizer introduced two kinds of plant hollow capsules. Hollow capsules made of hydroxypropyl cellulose-not conducive to human digestion, but made of pullulan-are extremely expensive and complicated. Experts in the industry agree that starch, as three essential nutrients for human beings, is the best raw material for producing plant hollow capsules.
In 2000, hollow starch capsules were formed, but due to the technical problems of starch fluidity, formability and properties, it has been impossible to realize industrial production.
In 2004, Hunan Erkang Pharmaceutical Co., Ltd. started the research and development project of starch capsules;
In 20 13, Erkang Pharmaceutical, together with senior scholars from Australia and Canada, took the lead in overcoming a number of core technical difficulties and realized the industrialization of empty starch capsules.
In 20 14, the world's first empty starch capsule industrial park was built in Liuyang Biomedical Park.
In 20 15, erkang starch hollow capsules will be fully sold and become the largest professional supplier of starch hollow capsules in the world.
Fourthly, compared with gelatin (the terminator of poison capsules)
20 12 April 15 CCTV Weekly Quality Report and Oriental Time and Space Report, some gelatin production enterprises decolorize and bleach leather scraps with quicklime, and then cook them into industrial gelatin, which is sold to Zhejiang Xinchang pharmaceutical capsule production enterprises and finally flows to pharmaceutical companies. After investigation, it was found that the content of heavy metal chromium in capsules used in 9 pharmaceutical factories 13 batches of drugs exceeded the standard, among which ......
What are the ingredients of capsules? Why and how do they melt?
Capsules are made of gelatin.
Gelatin is a derivative protein obtained by treating collagen which constitutes animal skin, tendons and bones with hot water.
When heated, the salt bonds and hydrogen bonds connecting peptide chains in animal collagen are broken, and the structure changes, becoming an elastic gel. Because the structure of gelatin itself has changed, it can not only be hydrolyzed by trypsin, but also be changed by pepsin, papain and so on.
Generally speaking, the drugs packaged in capsules are mostly harmful or volatile drugs to the mouth and esophagus. Gelatin is insoluble in oral mucosa and esophageal mucosa, but only changes in stomach, so it is the best material for making capsules.
What is the composition of capsule shell?
First, there are several kinds of capsule shell, one is gelatin capsule shell and the other is starch capsule shell;
1. Gelatin capsule shell: mainly made of animal leather. 12 had a toxic capsule incident, so be cautious when purchasing;
2. Starch capsule shell: capsule shell with plant starch as the main raw material is much safer than gelatin capsule shell, but you still need to be careful when purchasing, so as not to be deceived. It's best to choose a bigger brand.
Second, the main characteristics of starch capsule shell
(1) 100% natural cassava starch.
Starch capsules are made of 100% natural cassava starch and proper amount of purified water through a special process, and do not contain any chemical additives and preservatives.
(2) No animal-borne infectious diseases.
No animal-derived substances and animal protein are added in the production, which completely eliminates the potential safety hazards caused by mad cow disease and poison capsules.
(3) Non-transgenic
The starch used in the production does not use genetically modified varieties, and the raw materials are strictly controlled, and it has passed the international SGS non-genetically modified certification.
(4) No pesticide residue
Cassava, the raw material used in the production, is imported from Cambodia, and no pesticides are used in the organic planting process. At the same time, advanced technology is adopted in the production process to further ensure that the products are free of pesticide residues.
(5) No carcinogen residue.
Strictly control the production conditions, never use ethylene oxide to sterilize the products, and there will be no carcinogen residue.
(6) Take care of the stomach
Taking powder directly is easy to burn esophagus and gastric mucosa and cause ulcer. Some powders are too big, which are easy to choke into trachea and corrode trachea mucosa. Using empty starch capsules as carriers can protect the stomach and intestines well.
(7) no cross-linking reaction with drugs
Starch is a substance with stable molecular structure, which will not cross-link with aldehyde groups or other compounds to prevent internal substances from deteriorating and cross-linking due to capsules.
(8) The drug utilization rate and absorption effect are good.
The effective components in starch are more helpful to stimulate the activity of powder, which is beneficial to human absorption and increase the use efficiency of precious Chinese herbal medicines.
(9) It is easy to be accepted by people of special culture.
The raw material of empty starch capsules is pure starch, which is more in line with the eating habits of people with special religious beliefs and vegetarians. Products have passed the European Vegetarian Association certification, * * * certification and kosher certification.
(10) Easy to store and carry.
Starch hollow capsules have low requirements on temperature and humidity, and can be stored and carried under normal conditions.
Third, the delivery process.
BC 1500, the first empty capsule was born in Egypt;
1846, two-stage hard capsule manufacturing technology was patented in France;
1874, Detroit began the industrial manufacture of hard capsules, and introduced various models at the same time;
193 1 year, large-scale production of empty capsules began, accounting for 70% of all kinds of drugs;
During the period of 1986, the outbreak of mad cow disease from Britain to Europe made gelatin capsules fall into an unprecedented crisis of confidence, and people began to look for plant materials to replace gelatin.
During the period of 1997, Pfizer introduced two kinds of plant hollow capsules. Hollow capsules made of hydroxypropyl cellulose-not conducive to human digestion, but made of pullulan-are extremely expensive and complicated. Experts in the industry agree that starch, as three essential nutrients for human beings, is the best raw material for producing plant hollow capsules.
In 2000, hollow starch capsules were formed, but due to the technical problems of starch fluidity, formability and properties, it has been impossible to realize industrial production.
In 2004, Hunan Erkang Pharmaceutical Co., Ltd. started the research and development project of starch capsules;
In 20 13, Erkang Pharmaceutical, together with senior scholars from Australia and Canada, took the lead in overcoming a number of core technical difficulties and realized the industrialization of empty starch capsules.
In 20 14, the world's first empty starch capsule industrial park was built in Liuyang Biomedical Park.
In 20 15, erkang starch hollow capsules will be fully sold and become the largest professional supplier of starch hollow capsules in the world.
Fourthly, compared with gelatin (the terminator of poison capsules)
20 12 April 15 CCTV Weekly Quality Report and Oriental Time and Space Report, some gelatin production enterprises used quicklime to decolorize and bleach leather scraps, and then boiled them into industrial gelatin and sold them to Zhejiang Xinchang Medicine.
Capsule manufacturers eventually flow to pharmaceutical companies. Through investigation, it was found that the content of heavy metal chromium in capsules used in 9 pharmaceutical factories 13 batches of drugs exceeded the standard, and most of them exceeded the standard by more than 90 times.
......
What is capsule shell made of?
There are many kinds in capsule shell, including gelatin capsule shell and starch capsule shell, also called starch empty capsules.
Gelatin capsule shell: Mainly made of animal leather. There have been toxic capsule accidents before, so there are fewer people on the market now, so you need to buy them carefully;
Starch capsule shell: Mainly made of cassava starch. The main difference with gelatin is that you don't have to worry about poison capsule accidents, so it is relatively safe to eat.
You can look at the empty capsules of Erkang starch. I hope my answer is helpful to you.
What material is the capsule made of?
1~ hollow capsules are divided into hard hollow capsules, soft hollow capsules and enteric hollow capsules.
2~ # hard hollow capsules are widely used, including transparent (without pigment and titanium dioxide), translucent (with pigment but without titanium dioxide) and opaque (with titanium dioxide).
The main ingredients of 3 # hard hollow capsule are gelatin, the main ingredients of soft hollow capsule are gelatin and glycerol, and the main ingredients of enteric hollow capsule are gelatin or sodium alginate, and then the enteric materials such as pvp are used as the base coat, and then coated with a cap.
Will be digested, no harm.
What is capsule shell made of?
The most commonly used hollow capsules in medical capsules are gelatin capsules, including stomach-soluble capsules and enteric-coated capsules. Enteric-coated hollow capsules are made of gelatin and enteric materials. Unqualified capsule shell with specific color (can be specially prepared according to user's needs) and shape is harmful to some extent.
I wonder what capsules are made of.
Capsules are made of starch—
What is the skin of the capsule made of?
Most capsules are made of gelatin. Gelatin is widely used in many foods, such as pudding, candy, candied fruit, chewable tablets, sugar coating, food stuffing and dip. In food, gelatin can help food to solidify, thicken, stabilize and ventilate. It is a very popular food ingredient with rich nutrition and low fat content. Gelatin itself is a water-soluble protein extracted from collagen, which is the main natural protein component in connective tissue. Gelatin is obtained from the skin and bones of animals through a controlled extraction process. There are many kinds of gelatin. The capsule adopts medical grade gelatin, which meets the strict requirements for pharmaceutical products. The procedure of making capsules is to form a gelatin film on a stainless steel mold. Then the gelatin film is dried and hardened to form capsules, and then taken out of the mold. Generally, there are two kinds of molds, one is to make the capsule body, and the other is to make the capsule cap with a larger diameter.
What material is the capsule made of?
Hard empty capsules can be divided into "animal capsules" and "plant capsules":
1. Animal capsules are made of gelatin/gelatin as the main raw material and purified water. Gelatin is made from connective tissues such as cowhide, and is mainly composed of amino acids.
2. The plant capsule is made of hydroxypropyl methylcellulose (HPMC) as the main raw material and purified water. HPMC is made of fibers extracted from pine trees (non-transgenic plants). It is a General Safe Raw Material (GRAS) approved by FDA.
3. Color capsules have food pigments approved by the Department of Health, including red No.6 and No.7, yellow No.4 and No.5, and blue 1. In addition, titanium dioxide is used as a white pigment and a sunscreen in dosage forms.