Caught a cold how to treat measles?
Hello, my friend, the situation you described may be urticaria. Because of the different causes of urticaria, the treatment effect is also different, some are easy to cure, and some are difficult to treat. The specific treatment measures are as follows: 1. Remove the cause. Every patient should try to find the cause of the attack and avoid it. If it is caused by infection, the infected focus should be actively treated, and allergic drugs should be stopped for drug reasons; People who are allergic to food should not eat this kind of food after finding out the allergic food. 2. In order to avoid inducing factors such as cold urticaria, we should pay attention to keeping warm. Acetylcholine urticaria reduces exercise, sweating and mood swings, and contact urticaria reduces contact opportunities. 3. Antihistamines are the most commonly used drugs to treat various types of urticaria. Most patients can get satisfactory curative effect after antihistamine treatment, and a few patients are stubborn. For intractable urticaria, the dosage can be increased or combined with medication. H 1 receptor antagonists have strong antihistamine and anti-inflammatory mediators, and have good therapeutic effects on various types of urticaria. Commonly used H 1 receptor antagonists include diphenhydramine, cyproheptadine, chlorpheniramine, Avastin, cetirizine, mizolastine, loratadine, ebastine (10mg/d), azelastine (4mg/d), desloratadine (5mg/d) and so on. When monotherapy fails, two different types of H 1 receptor antagonists can be used together or in combination with H2 receptor antagonists. Commonly used H2 receptor antagonists include cimetidine, ranitidine and famotidine. It is reported that the combination of H 1 and H2 receptor antagonist has synergistic effect, which can enhance the effect of H 1 antagonist. H2 receptor antagonists are ineffective when used alone. If two or more antihistamines are H 1 receptor antagonists, we should choose antihistamines with different structures, or strong antihistamines combined with weak antihistamines, or antihistamines with drowsiness and sedation combined with antihistamines without drowsiness, such as mizolastine and cetirizine. Antaile has strong antihistamine, anticholinergic and sedative effects, and also has good antipruritic effect. It is effective for acute and chronic urticaria and cold urticaria. Doses vary from person to person and vary greatly from individual to individual. The initial dose for adults is 25mg each time, 3 ~ 4 times/d; And it can be gradually adjusted to 50 ~ 100 mg /d each time, 3 ~ 4 times/d. If it is ineffective to use alone, it can be considered to be combined with other drugs. Doxepin is a tricyclic antidepressant, which is mainly used to treat depression and anxiety. This drug also has strong resistance to H 1 and H2 receptors. It is reported that doxepin, as an antagonist of H 1, is more than 700 times stronger than diphenhydramine and 50 times stronger than antipyrine. As an H2 antagonist, it is 6 times stronger than cimetidine, and the dosage is 25mg each time, three times a day. It is especially effective for chronic urticaria with few side effects. Doxepin is a better choice for urticaria patients whose traditional antihistamines are ineffective. 4. Choose drugs that can inhibit mast cell degranulation and thus reduce histamine release. (1) terbutaline sulfate, a β 2 adrenergic receptor promoter, can increase the concentration of cAMP in vivo, thus inhibiting mast cell degranulation. The dosage is 2.5 ~ 5 mg each time, three times a day, or subcutaneous injection: 0.25 ~ 2.5~5mg for adults each time. (2) ketotifen; The maximum dose per time is 1mg, three times a day. By increasing the concentration of cAMP in the body, the degranulation of mast cells is inhibited, and the release of inflammatory mediators (such as histamine and slow-response substances) is prevented. Its inhibitory effect is stronger and faster than that of sodium cromoglycate, and it can be taken orally. (3) cromoglycine: It can block the combination of antigen and antibody and inhibit the release of inflammatory mediators. Adults inhale 20mg each time, three times a day. If combined with glucocorticoid, the dosage of glucocorticoid can be reduced and the curative effect can be enhanced. (4) tranilast 100 mg, three times a day. Reduce histamine release by stabilizing mast cell membrane. 5. Glucocorticoid has strong anti-inflammatory and anti-allergic effects. It can stabilize mast cell membrane and lysosomal membrane and inhibit the release of inflammatory mediators and lysosomal enzymes; Can contract blood vessels and reduce exudation. Has good curative effect on urticaria, especially on acute measles, serum urticaria and stress urticaria. Some serious types of urticaria are accompanied by obvious systemic symptoms, such as high fever, extensive rash, abdominal cramps, hypovolemia and hypotension, heart damage, central nervous system symptoms, throat and respiratory tract obstruction symptoms and so on. Should be treated with glucocorticoid. Because glucocorticoid has certain side effects, it is easy to rebound after stopping taking medicine. Therefore, mild patients can be controlled by antihistamines in general, and these drugs are not always used. Commonly used drugs and dosages are as follows: ① Prednisone 40 ~ 80 mg/d, taken orally for 3 ~ 4 times; ② Triamcinolone acetonide: daily 12 ~ 16 mg, orally. ③ Dexamethasone 6 ~ 9 mg/d, taken orally for 3 ~ 4 times; ④ Diprosone 1ml, intramuscular injection, once a month 1 time. After the disease was controlled, it was changed to oral preparation. In case of emergency, hydrocortisone 200 ~ 400 mg, dexamethasone 5 ~ 20 mg or methylprednisolone 40 ~ 120 mg should be given intravenously. 6. Immunosuppressants When patients with chronic urticaria have an autoimmune foundation and their condition is repeated, and the above treatment cannot achieve satisfactory results, immunosuppressants can be used. Cyclosporine has a good effect. Azathioprine, cyclophosphamide, methotrexate and immunoglobulin can all be tried, and tripterygium wilfordii has a certain effect. 7. Nonspecific antiallergic therapy and other therapies 10% calcium gluconate injection 10ml, 1 time /d, intravenous injection; Intravenous infusion of procaine, with a dose of 0.25~0.5g each time, adding 500ml of 5% glucose injection, 10% sodium thiosulfate 10ml, 1 time /d, intravenous injection, autotherapy or tissue therapy; Intramuscular injection or acupoint injection of histamine globulin: 0.25~0.5g/ time, 3 times /d, orally; 0.25~0.5g/ time, diluted with 5% glucose solution, intravenous drip; 6- aminocaproic acid, 2g each time, 3 times a day, taken orally; 4 ~ 6g/ time plus 5% glucose solution for intravenous drip; Reserpine 0.25mg /d, 3 times /d, and aminophylline 0. 1 ~ 0.2g, 3 times /d; Transfer factor 1u is injected subcutaneously into the medial arm twice a week, * * * 6 ~ 10 times, which has a certain effect on chronic urticaria. BCG polysaccharide nucleic acid 1mg, intramuscular injection, 1 time, once every other day. The effect of the above drugs alone is generally not ideal, and they are usually used in combination with antihistamines to enhance the effect and reduce the chance of recurrence. 8. Some special circumstances, such as urticaria caused by infection, should be treated with appropriate anti-infective drugs according to the infection. (1) Among the antihistamines for the treatment of cold urticaria, cyproheptadine, doxepin, ketotifen, hydroxyzine and mizolastine have better effects. Vitamin e 100 ~ 200mg, 3 times /d, cinnarizine 25mg, 3 times /d can be used in combination with H2 receptor antagonist. Azatadine (1mg, three times a day) has a good effect on cold urticaria through antihistamines, anticholinergic drugs and serotonin. You also need (1) to protect yourself from sudden cooling; ② Among antihistamines, cyproheptadine, doxepin and ketotifen were selected; ③ Sensitize by gradually adapting to low temperature environment and cold water. (2) For solar urticaria, besides antihistamines, such as hydroxyzine and chlorpheniramine, chloroquine 125 ~ 250 mg/d, hydroxychloroquine 100 ~ 200 mg/d, thalidomide 25 ~ 50 mg/d, and HCH (Homology) as far as possible. ④ Apply sunscreen; ⑤ Avoid taking photosensitive drugs and food. (3) For cholinergic urticaria, ① an anticholinergic antagonist, H 1 receptor, such as polima 5mg twice a day or10 mg, should be taken before going to bed; Anisodamine 10mg is also acceptable, 2 ~ 3 times/d; (2) Reduced glutathione has a certain curative effect, and its mechanism may be that cholinesterase is activated to hydrolyze acetylcholine; (3) strenuous exercise should be properly restricted; (4) desensitization can be achieved by gradually increasing water temperature and exercise to increase tolerance. (5) It is reported that the combined application of telafilatine and polypyridine mesylate (anticholinergic drug) is very effective.