On June 4th, 65438+ 10/KLOC-0, it was learned from China University of Science and Technology that the team of Academician Yu Shuhong was based on? Break off the relationship? This natural phenomenon deeply explores the microstructure and mechanical properties of lotus silk fiber, and inspired by this, a kind of lotus silk-like bacterial cellulose hydrogel fiber which can be used for surgical suture is developed. The related research achievement 65438+ was published in Nanocommunication on1October 5th.
Researchers processed bacterial cellulose (BC) hydrogel into hydrogel fiber (BHF) with lotus-like micro-helix structure, which has high strength and toughness, as well as excellent hydrophilicity and biocompatibility. In addition, the bionic spiral structure endows the material with elasticity similar to human skin. When the wound is deformed, BHF can effectively buffer and absorb energy, realize synchronous deformation with human tissue, and avoid secondary injury caused by cutting the wound. Compared with traditional cotton thread or polymer thread, hydrogel fiber suture has the characteristics of high biocompatibility, high water content, low irritation and low friction resistance, and has obvious advantages in protecting damaged tissues, promoting wound healing and reducing adverse reactions, so it is expected to become the next generation of new high-end surgical suture.
Different from hydrogels formed by polymer chains, BHF with spiral structure is a hydrogel composed of three-dimensional nanofiber network, so it has unique mechanical properties. At the same time, the three-dimensional nanofiber network of bacterial cellulose hydrogel makes BHF have more than 90? The high strength of MPa. Its unique cellulose nanofiber network and bionic spiral structure bring uniqueness? Stretchable, inelastic? Its mechanical properties lay a good foundation for its application in the field of high-end surgical suture.
In addition, the porous structure of nanofiber hydrogel also enables BHF to adsorb antibiotics or anti-inflammatory drugs and release them continuously at the wound, thus playing the role of anti-inflammation and accelerating wound healing. Based on this bionic design, BHF is expected to show its unique application potential in more fields of medical materials. It is reported that the patents related to this material have been approved and authorized.