Can eating irbesartan tablets and bisoprolol fumarate tablets cause stomach pain in hypertension?

Hello, irbesartan belongs to angiotensin receptor antagonist, and bisoprolol belongs to β receptor blocker. The combination of these two drugs can improve ventricular remodeling, which is the mainstream antihypertensive drug and can be taken together. Irbesartan is contraindicated in patients with renal artery stenosis and hyperkalemia. Bisoprolol is contraindicated in patients with bradycardia, bronchial asthma and severe heart failure.