Evaluation of compound artemether

Artemisinin extracted from Artemisia annua is recognized by the international community as one of the two most influential drugs in China. Artemisinin-based combination therapy can take effect in 3 days, which is 4 days less than traditional chloroquine therapy. In clinical application for more than 30 years, no drug resistance of plasmodium was found. At the beginning of 2004, the World Health Organization accepted the grant from the Global Fund, and planned to invest $65.438+0 ~ 200 million every year in five years to buy compound drugs with Artemisia annua as the first choice of global antimalarial drugs for African countries. Since 199 1, a total of 63 countries and regions and relevant international patent organizations have applied for the patent of compound artemether. By 2002, they had obtained the invention patent of compound drugs in 49 countries and regions such as China, the United States, Japan, Australia and Europe, becoming the first chemical in China to obtain a patent internationally, and also enjoying the invention patent protection of compound drugs internationally.