The article points out that the so-called "brush acid" is actually a kind of chemical rejuvenation, also known as chemical peeling, which is to smear chemicals on the skin surface, so that the skin can be controlled and the new skin can be regenerated.
From the perspective of skin structure, the outermost layer of skin is epidermis, which can be subdivided into five layers, and the outermost layer is stratum corneum. The stratum corneum is mainly composed of 10 to 20 layers of flat dead cells without nucleus. When these cells fall off, the cells located in the basal layer will be pushed upward to form a new stratum corneum. The whole alternation process takes about 28 days. The so-called "promoting new skin regeneration" refers to accelerating the alternating process of stratum corneum.
Cosmetics are industrial products for daily use with the purpose of cleaning, protection, beautification and modification, and there are strict requirements on the addition amount of "acid". Although the allowable concentration is relatively low, it can still achieve certain cleaning, exfoliation, anti-inflammatory and antibacterial effects. Salicylic acid and azelaic acid are the most widely used in cosmetics.
Shenzhen Xuanjia Biotechnology Co., Ltd. focuses on the research of supramolecular science and technology, and uses supramolecular modification technology to combine the advantages of salicylic acid with betaine and matrine to form unique supramolecular products that can gently improve the skin: Xuanpoqing (betaine salicylic acid) and Xuanjingyan (matrine salicylic acid). Its precursor is taken from the natural active ingredients in the catalogue of cosmetic raw materials. After self-assembly, it can promote the absorption of effective components, improve the bioavailability of effective components, reduce the irritation of precursor substances, and increase the water solubility and stability of effective components.
According to the three-dimensional structure of Xuanpoqing (betaine salicylic acid complex), N and O on betaine molecule form two hydrogen bonds with phenolic group and carboxyl group on salicylic acid molecule as hydrogen bond donors, and the remaining atoms in the molecule are spontaneously arranged into a regular and stable three-dimensional structure through π -π stacking, forming a multifunctional supramolecular crystal with stable structure.
Patent numbers: CN 1 10236974 A, CN 1 10327240 A.
Technical advantages:
0. 1.25 mg/ml Xuandouqing acted on keratinocytes stimulated by UVB, and the inflammatory factors (IL-8, TNF-α, IL- 1α) and inflammatory mediators (PGE2) decreased by 34.0%, 53.59% and 21.
When the concentration of Xuandu was 0. 1.25 mg/ml, the cell phase activity was 98.04%, and there was no significant difference between the cell state and the solvent control group under the microscope. Xuandouqing is non-toxic and safe in the range of 0. 125 mg/mL.