The relationship between the growth factors and stem cell technology in Maria’s Jeunesse Revitalizing Youth Essence is: The patented technology of Maria’s Jeunesse Revitalizing Youth Essence provides the same main ingredients as those found on natural skin. Growth factors. As we age, the growth factors on the skin will also decrease, resulting in wrinkles and thinning of the skin. By using Maria Merchant Jeunesse Revitalizing Youth Essence every day, these growth factors can re-stimulate cells. Regenerate and also repair damaged cells.