Application number: 201080031317.6438+0.
Date of application: 20 10-05- 10
Abstract: The present invention relates to enantiomerically enriched β? β and other amino acid derivatives? A new method for synthesizing enantiomerically enriched bioactive molecules such as sitagliptin through amino esters. The key step includes the resolution of raceme with mandelic acid.
Applicant: Generix (UK) Limited.
Address: Hertfordshire, England
Inventors (designers): Vinayak Govind Goree, Mahesh Kumar Gada, Karpoori Yanka, Bosler and suresh Sinde.
Main classification number: C07D487/04 (2006 2006,438+0) i.
Classification number: C07D487/04 (2006.01) IC07C227/16 (2006.01) IC07C227/34 (2006.01) IC07C229/.