Zhang Zhiling’s tutor at the School of Chemistry and Molecular Sciences of Wuhan University

Obtained a bachelor's degree from the Department of Chemistry, Jilin University, in July 1997.

Obtained a doctorate degree from the School of Chemistry and Molecular Sciences, Wuhan University, in November 2002.

In July 2001, he stayed at the school as an outstanding talent to work in advance.

In October 2003, he went to the Ecole Normale Supérieure (ENS) in France for one year of postdoctoral work.

Promoted to associate professor in 2005,

Exceptionally promoted to professor in 2008.

Currently, he is mainly engaged in research on microfluidic chips, bioelectric analysis and nano-biomedical sensing. Executive director of Hubei Instrument Association. He is a key member of the "Basics and Applications of New Biomedical Probe Technology" innovation research group of the National Foundation of China and the "Basic Research on Applications of Chemical Biology" of the Ministry of Education.

In 2006, he won the first prize of the Natural Science Award of the Higher Education Institutions Science and Technology Award of the Ministry of Education (the second completer). Published more than 60 SCI papers. Applied for 15 national invention patents (8 have been authorized). One of the leading teachers of Hubei Province and national quality courses (Wuhan University "Analytical Chemistry").

1. National Natural Science Foundation of China General Project (20875072) "Development of Integrated Cell Analysis Microfluidic Chip"

2. National Natural Science Foundation of China Youth Fund (20305011) "Surface Analysis of DNA-Protein Interactions" Chemical Research"

3. National Ministry of Science and Technology 863 Special Project (2006AA03Z320) "Research and Development of Fluorescence-Magnetic-Biological Targeting Trifunctional Nanospheres for Highly Sensitive and Rapid Diagnosis"

4. Scientific Research Start-up Fund for Returned Overseas Students of the Ministry of Education (Jiaowai Siliu [2005] No. 383) "Application of Microfluidic Chip Channel Surface Biofunctionalization and Biochemical Analysis" 1. National Natural Science Foundation of China Innovative Research Group Project (20621502) " "Basics and Applications of New Biomedical Probe Technology"

2. "Basic Research on the Application of Microfluidics in Chemistry and Biomedicine" sub-project of the National Ministry of Science and Technology 973 Project (2007CB714507) "Diagnosis of Infectious Diseases" "Research on new microfluidic methods and their applications"

3. National Major Scientific Research Program Project of the Ministry of Science and Technology (s973) "New technology for real-time detection of fluorescence nanometer interactions between viruses and cells and visualization of dynamic processes" (2006CB933101) "New technology for pathogen detection based on fluorescent nanomaterial labeling"

4. National Natural Science Foundation of China major project "Basic research on microfluidic biochemical analysis systems" sub-project (20299034) "Microfluidic Research on cell manipulation and biochemical component analysis methods in control systems"

5. National Science and Technology Research Program "Bio-Nano and Medicine" National Nanotechnology Major Special Project (2003BA310A22) "New Nano-Biomedical Materials- "Research and Development of Multifunctional Quantum Dots" (Deputy Team Leader)

6. Ministry of Education Innovation Team Development Plan (Teaching Technology Letter [2006] No. 8 IRT0543) "Basics of Chemical Biology Applications" 1. Zhi-Ling Zhang, Dai-Wen Pang*, Rong-Ying Zhang, Jia-Wei Yan, Bing-Wei Mao, Yi-Peng Qi. Investigation of DNA Orientation on Gold by EC-STM. Bioconjugate Chem. 13(1) (2002)104 -109. (Impact factor 3.766)

2. Zhi-Ling Zhang, C. Crozatier, M. Le Berre, Yong Chen, In-Situ Bio-functionalization and Cell Adhesion in Microfluidic Devices. Micro and Nano Engineering International Conference (2004) 40-41.

3. Zhi-Ling Zhang, Dai-Wen Pang*, Hong Yuan, Ru-Xiu Cai, Héctor D. Abruamp;ntilde;a. Electrochemical DNA Sensing Based on Gold Nanoparticle Amplification. Analytical and Bioanalytical Chemistry 381 (2005) 833–838. (Impact factor 2.098)

4. Yuan-Hai Zhu, Zhi-Ling Zhang*, Dai-Wen Pang, Electrochemical oxidation of theo

phylline at multi-wall carbon nanotube modified glassy carbon electrode. J. Electroanal. Chem. 581 (2005) 303-309. (Impact factor 2.228, corresponding author)

5. Zhi-Ling Zhang, C. Crozatier, M. Le Berre, Yong Chen, In-Situ Bio-functionalization and Cell Adhesion in Microfluidic Devices. Microelectronic Engineering 78-79 (2005) 556-562.

6. Rong-Ying Zhang, Dai -Wen Pang*, Zhi-Ling Zhang, Jia-Wei Yan, Jian-Lin Yao, Zhong-QunTian, ??Bing-Wei Mao, Shi-Gang Sun. Investigation of Ordered ds-DNA Monolayers on Gold Electrodes. J. Phys. Chem . B, 106(43)(2002)11233-11239. (Impact factor 3.843)

7. Ye-Fu Wang, Dai-Wen Pang*, Zhi-Ling Zhang, Hu-Zhi Zheng, Jun -Ping Cao, Jun-Tao Shen. Visual Gene Diagnosis of HBV and HCV Based on Nanoparticle Probe Amplification and Silver Staining Enhancement. Journal of Medical Virology, 70(2)(2003)205-211.

8 . Zhe-Xue Lu, Lei Zhou, Zhi-Ling Zhang, Wan-Liang Shi, Zhi-Xiong Xie, Hai-Yan Xie, Dai-Wen Pang*, Ping Shen. Cell damage induced by photocatalysis of TiO2 thin films. Langmuir, 19(21)(2003)8765-8768. (Impact factor 3.295)

9. Hui-Hong Liu, Zhi-Quan Tian, ??Zhe-Xue Lu, Zhi-Ling Zhang, Min Zhang, Dai- Wen Pang*. Direct Electrochemistry and Electrocatalysis of Heme-proteins Entrapped in Agarose Hydrogel Films. Biosensors amp; Bioelectronics, 20(2)(2004)294-304. (Impact factor 3.251)

10. Jing- Xue Shi, Xian-En Zhang, Wei-Hong Xie, Ya-Feng Zhou, Zhi-Ping Zhang, Jiao-Yu

Deng, Anthony E. G. Cass, Zhi-Ling Zhang, Dai-Wen Pang, Cheng-Gang Zhang. Improvement of Homogeneity of Analytical Biodevices by Gene Manipulation. Anal. Chem. 76 (3) (2004) 632-638. (Impact factor 5.450 )

11. Guo-Ping Wang, Er-Qun Song, Hai-Yan Xie, Zhi-Ling Zhang, Zhi-Quan Tian, ??Chao Zuo, Dai-Wen Pang*, Dao-Cheng Wu and Yun -Bo Shi. Biofunctionalization of fluorescent-magnetic-bifunctional nanospheres and their applications. Chem. Commun. (34) (2005) 4276-4278. (Impact factor 3.997)

12. Min Xie, Hui-Hui Liu, Ping Chen, Zhi-Ling Zhang, Xiao-Hui Wang, Zhi-Xiong Xie, Yu-Min Du, Bo-Qun Pan, Dai-Wen Pang*. CdSe/ZnS-labeled carboxymethyl chitosan as a bioprobe for live cell imaging . Chem. Commun.(2005) 5518-5520. (Impact factor 3.997)

13. Sheng-Fu Wang, Ting Chen, Zhi-Ling Zhang, Xin-Cheng Shen, Zhe-Xue Lu, Dai -Wen Pang*, Kwok-Yin Wong. Direct Electrochemistry and Electrocatalysis of Heme Proteins Entrapped in Agarose Hydrogel Films in Room-Temperature Ionic Liquids. Langmuir 21(2005) 9260-9266. (Impact Factor 3.295)

14. Hai-Yan Xie, Jian-Gong Liang, Yi Liu, Zhi-Ling Zhang, Dai-Wen Pang*, Zhi-Ke He, Zhe-Xue Lu, Wei-Hua Huang. Preparation and Characterization of Overcoated II-VI Quantum Dots. Journal of Nanoscience and Nanotechnology, 5(6) (2005) 880-886.

15. Hai-Yan Xie, Chao Zuo, Yi Liu, Zhi-Ling Zhang, Dai-Wen Pang*, Xiao-Lan Li, Jian-Ping Gong, Calum Dickinson, Wuzong Zhou, Cell-t

argeting Multifunctional Nanospheres with both Fluorescence and Magnetism. Small, 1 (2005) 506-509.

16. Hu-Zhi Zheng, Hui-Hui Liu, Shao-Xing Chen, Zhe-Xue Lu, Zhi- Ling Zhang, Dai-Wen Pang*, Zhi-Xiong Xie*, Ping Shen. Yeast transformation process studied by fluorescence labeling technique. Bioconjugate Chem. 16(2) (2005) 250-254. (Impact factor 3.766)

17. Zhe-Xue Lu, Zhi-Ling Zhang, Ming-Xi Zhang, Hai-Yan Xie, Zhi-Quan Tian, ??Ping Chen, Hua Huang, Dai-Wen Pang*. Core/shell Quantum Dots-photosensitized Nano -TiO2 Films: Fabrication and Application to the Damage of Cells and DNA. J. Phys. Chem. B, 109 (2005) 22663-22666.

18. Zhang Zhiling, Zuo Chao, Pang Daiwen, DNA and Metals Surface electrochemical study on the interaction of osmium complexes, Acta Chemica Sinica, 60 (22) (2005) 2069-2076

Patent applied for:

1. Pang Daiwen, Wang Yefu, Zhang Zhiling, Cao Junping, Cai Ruxiu, Zheng Huzhi. Invention patent: Nanoparticle labeled gene probe and its preparation method and application. Patent number: ZL 01 1 33527.0, Certificate number: No. 154129, Patent application date: 2001.9.30., Authorization announcement date : 2004.5.5.

2. Pang Daiwen, Xie Haiyan, Liu Yi, Zuo Chao, Zhang Zhiling. Invention patent: Preparation of fluorescent magnetic multifunctional nanomaterials. Application number: 200310111290.9, application date: 2003.10.29.

3. Pang Daiwen, Liu Yi, Zhang Zhiling. Invention patent: A method for making oil-soluble quantum dots water-soluble. Application number: 00410013332.x, application date: 2004.6.22.

4. Pang Daiwen, Lu Zhizhi, Zhang Zhiling. Invention patent: Preparation method of quantum dot nano-titanium dioxide composite film. Application number: 200510018188.3, ??application date: 2005.1.24.

5. Pang Daiwen, Xie Min, Zhang Zhiling, Du Yumin. Invention patent: A method for preparing sugar biofunctionalized water-soluble quantum dots - two-phase ultrasonic method. Application number: 200510018234.X, Application date: 2005.2.1.

6. Pang Daiwen, Xie Min, Zhang Zhiling, Du Yumin. Invention patent: A method for preparing sugar biofunctionalized water-soluble quantum dots - grinding method. Application number: 200510018233.5, Application date: 2005.2.1.

7 . Pang Daiwen, Xie Haiyan, Wang Guoping, Zhang Zhiling, Song Erqun, Shi Yunbo. Invention patent: Trifunctional nanospheres. Application number: 200510079227.0, application date: 2005.5.23.

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8. Dai-Wen Pang, Hai-Yan Xie, Guo-Ping, Wang, Zhi-Ling Zhang, Er-Qun Song, Yun-Bo Shi. Tri-functional nanospheres. US Patent, Application No. 11 /335, 380, Application date: May 24, 2005.