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Overview of the contents of this article: 1. The efficacy and function of borneol 2. What are the functions of borneol 3. The efficacy of borneol 4. What are the functions of borneol? 5. What is the function of the "borneol" in the medicine? Efficacy and role of borneol Borneol is used to treat stroke, stupor, febrile coma, epilepsy and phlegm confusion, breathlessness, deafness, laryngeal paralysis, aphthous ulcer, otitis media, carbuncle, hemorrhoids, eye cysts, and pinworms.
Bornolum unblocks various orifices, dissipates stagnant fire, removes nebula, improves eyesight, reduces swelling and relieves pain.
It has similar effects to camphor and has analgesic and antiseptic effects; in vitro (plate mixing method), higher concentrations (0.5%) have antibacterial effects and can be used for neuralgia and anti-inflammation.
It is easily absorbed by mucous membranes and subcutaneous tissues, and is excreted after being combined with glucuronic acid in the body.
Using rats for experiments, sodium glucuronate antagonized the toxicity of borneol, and the excretion of glucuronic acid in urine increased.
What are the functions of borneol? Borneol, also known as borneol, tangerine slice, dipterocarp, plum blossom borneol, borneol, plum blossom, borneol, plum ice, etc., is a plant of Dipterocarpaceae family. The crystal obtained by extracting fragrant resin and volatile oil processed products is almost pure dextroborneol.
It can also be synthesized by chemical methods.
It can be used to treat coma due to closed syndrome, red and swollen eyes, sore throat, sores, swelling and pain, and non-astringent ulcers.
Borneol: pungent, bitter, slightly cold in nature.
It has the functions of rejuvenating the mind, clearing away heat, reducing swelling and relieving pain.
Used for delirium, febrile disease, high fever and coma, stroke with phlegm, qi, evil, sores and swelling and pain, aphtha, sore throat, red and swollen eyes, eye diseases, gum swelling and pain wait.
Modernly used for coronary heart disease and angina pectoris.
Pregnant women cannot eat borneol. It has no other side effects. 1. It is used to treat coma.
This product has the effect of resuscitating and awakening the mind, but it is not as good as musk. The two are often used in conjunction with each other.
However, borneol is slightly cold in nature and is a cooling product. It is suitable for treating coma due to fever, phlegm-heat internal obstruction, syncope due to heat-heat, infantile convulsions and other thermal obstructions. It is often combined with bezoar and musk deer. , Coptis chinensis and other compatibility, such as Angong Niuhuang Pills.
If it is combined with resuscitating drugs that warm the body and dispel cold and have a warmer nature, it can also treat cold syndrome.
2． Used for red and swollen eyes, sore throat, and aphthous ulcers.
This product is bitter and cold, has the effect of clearing away heat, relieving pain and reducing swelling. It is a commonly used medicine in the Department of Otology.
To treat red, swollen and painful eyes, eye drops alone are effective: it can also be combined with calamine, borax, bear bile, etc. to make eye drops, such as Babao eye drops.
To treat sore throat and sores on the mouth and tongue, it is often mixed with borax, cinnabar, and xuanming powder into fine powder, and then blown and applied to the affected area, such as Bingboran powder.
To treat wind-heat throat paralysis, "Binhu Ji Simplified Prescriptions" combine it with rushes, cork, and alum into powder, and blow on the affected area to get the effect.
3. It is used for swelling and pain of sores and ulcers that are not astringent after ulceration.
This product also has heat-clearing, detoxifying, antiseptic and muscle-building effects.
Use this product with cinnabar and sesame oil to make a reddish-brown ointment for external use, which can treat burns; it can be used with elephant bark, dried blood, and frankincense to treat sores that are not astringent after ulceration, such as Shengji Powder .
In modern times, this product is dissolved in walnut oil and dropped into the ears to treat acute and chronic suppurative otitis media, and has a good effect.
Other names of borneol: borneol, borneol, borneol, plum blossom, borneol, plum blossom, borneol, borneol, plum blossom, moxa, dipterocarpaceae, and dipterocarps are evergreen trees.
The Latin literary name of dipterocarps: DryobalanopsaromaticaGaertn.f. Resin processed products, or crystals obtained by distillation and cooling of dipterocarps trunks, are called "borneol borneol", also known as "plum slices".
It is made from the sublimated leaves of the perennial herbaceous plant Blumeabalsamifera DC.
Nowadays, turpentine, camphor, etc. are mostly used, which are synthesized by chemical methods and are called "mechanical borneol".
Dipterocarps are mainly produced in Southeast Asia and have been introduced in Taiwan, my country; Aina incense is mainly produced in Guangdong, Guangxi, Yunnan, Guizhou and other places.
The finished product of borneol must be stored in a cool place and airtight.
For grinding into powder.
A terpene.
Molecular formula C10H180.
Also known as borneol or 2-borneol.
White translucent hexagonal crystals, smelling like camphor.
Dextral borneol is leaf-shaped or hexagonal flake crystal; melting point is 208℃, boiling point is 212℃, relative density is 1.011 (20/4℃), specific optical rotation +37.7 (ethanol); soluble in Ethanol, ether and benzene.
Levorotary borneol is a hexagonal flake crystal; melting point is 208.6°C, boiling point is 210°C (779 mm Hg), relative density is 1.1011 (20/4°C), -37.74° (ethanol); soluble in ethanol , ether, acetone and benzene.
Racemic borneol is a leaf-shaped crystal; melting point is 210.5°C, easy to sublimate, relative density 1.011 (20/4°C); soluble in ethanol, ether and benzene.
Camphor is generated during oxidation.
Borneol can be produced by reducing camphor with metallic sodium in an ethanol solution; or by esterifying pinene with oxalic acid in the presence of a catalyst and then hydrolyzing it.
Borneol is widely used in the preparation of rosemary and lavender flavors, and is used in traditional Chinese medicine and Chinese ink.
The nature and flavor are acrid, bitter and slightly cold.
Guixin, spleen, lung hydrocarbons.
Effects: Refreshing the mind, clearing away heat and relieving pain.
Application 1, used to treat coma.
This product has the effect of resuscitating and awakening the mind, but it is not as good as musk. The two are often used in conjunction with each other.
However, borneol is slightly cold in nature and is a cooling product. It is suitable for treating coma due to fever, phlegm-heat internal obstruction, syncope due to heat-heat, infantile convulsions and other thermal obstructions. It is often combined with bezoar and musk deer. , Coptis chinensis and other compatibility, such as Angong Niuhuang Pills.
If combined with resuscitating medicines that warm the body and dispel cold and have a warmer nature, it can also treat cold syndrome.
2． Used for red and swollen eyes, sore throat, and aphthous ulcers.
This product is bitter and cold, has the effect of clearing away heat, relieving pain and reducing swelling. It is a commonly used medicine in the Department of Otology.
To treat red, swollen and painful eyes, eye drops alone are effective: it can also be combined with calamine, borax, bear bile, etc. to make eye drops, such as Babao eye drops.
To treat sore throat and sores on the mouth and tongue, it is often mixed with borax, cinnabar, and xuanming powder into fine powder, and then blown and applied to the affected area, such as Bingboran powder.
To treat wind-heat throat paralysis, "Binhu Ji Simplified Prescriptions" combine it with rushes, cork, and alum into powder, and blow on the affected area to get the effect.
3. It is used for swelling and pain of sores and ulcers that are not astringent after ulceration.
This product also has heat-clearing, detoxifying, antiseptic and muscle-building effects.
Use this product with cinnabar and sesame oil to make a reddish-brown ointment for external use, which can treat burns; it can be used with elephant bark, dried blood, and frankincense to treat sores that are not astringent after ulceration, such as Shengji Powder .
In modern times, this product is dissolved in walnut oil and dropped into the ears to treat acute and chronic suppurative otitis media, and has a good effect.
In addition, this product is used to treat coronary heart disease, angina pectoris and toothache, and has certain curative effects.
Usage and dosage: Take into pill powder, 0.03~0.1g each time.
Appropriate amount for external use.
Not suitable for decoction.
Use with caution by pregnant women.
Experiments have shown that this product can induce labor in mid- and late-term pregnant mice.
Preparation 1. "Newly Revised Materia Medica": "Treats evil spirits in the heart and soul, accumulation of rheumatism, deafness, improves eyesight, and removes red eyes and skin nebula.
" "Compendium of Materia Medica": "Cures laryngeal paralysis, brain pain, flat nose, toothache, etc." Pain, typhoid, tongue protrusion, and acne in children.
Opens all the orifices and disperses stagnant fire.
" "Yilin Zuan Yao": "Bornolum mainly disperses stagnant fire and can penetrate into the bones. For heat, it can cure epilepsy, phlegm, sore throat, distended tongue, toothache, deafness, sneezing, red eyes and floating nebula, invagination of acne, insecticide, hemorrhoids, inducing birth, unprotected sex, and can also promote muscle growth and relieve pain. < /p>
However, it is scattered and easily exhausted, and it is ultimately cold.
” 2. Borneolum borneol contains dexborneborneol, as well as terpenes such as rythromycin, β-elemene, and caryophyllene, as well as oleanolic acid, myric acid, asiatic acid, borneol, and cocadiol. and other triterpene compounds.
Ai tablets contain L-borneol.
The machine-made borneol is racemic mixed borneol.
The local application of borneol can slightly stimulate sensory nerves, and has certain analgesic and mild antiseptic effects.
It is rapidly absorbed through the mesentery and can pass through the blood-brain barrier within 5 minutes of administration. It accumulates in the brain for a long time and the amount is quite high. This provides a preliminary experimental basis for the aromatic resuscitation effect of borneol.
Higher concentration (0.5%) has inhibitory effect on Staphylococcus aureus, Streptococcus aureus, Diplococcus pneumoniae, Escherichia coli and some pathogenic skin fungi.
It has the effect of inducing labor in mid- and late-term pregnant mice.
Borneol is a processed product of dipterocarps, a plant of the family Dipterocarpaceae. Its ingredients include dexborneborneol, β-elemene, caryophyllene, etc.
This medicine has pungent taste and cold nature, and has the functions of clearing various orifices, dispersing stagnant fire, reducing swelling and removing nebula.
In beauty prescriptions, it is used to clear away heat, dissipate fire, eliminate filth and transform turbidity. It is used to treat bad breath, body qi, sores, swollen boils and other diseases caused by blood heat and internal heat accumulation. .
3. Borneol properties: Borneol is a colorless, transparent or white translucent flaky crisp crystal; it has a fragrant aroma, pungent and cool taste; it is volatile, easy to sublimate, and produces thick smoke when ignited. Lighted flame.
This product is easily soluble in ethanol, chloroform, gasoline or ether, and almost insoluble in water.
The melting point of D-borneol is 208℃, the boiling point is 212℃, the melting point of L-borneol is 204℃, the boiling point is 210℃ 4. Quality standard: (2000 edition of Chinese Pharmacopoeia) Appearance: Melting point: 205-210℃ Identification: Vanillin Sulfuric Acid Color Reaction Camphor Odor Reaction Check: PH Value: Neither phenolphthalein nor methyl red should appear red.
Non-volatile matter: less than 0.035% Moisture: Petroleum ether is dissolved and should be clarified Heavy metals: no more than 5ppm Content determination: Use GC method, use methyl salicylate as internal standard, and use borneol standard to calculate the correction Factor, test sample, borneol content: not less than 55%.
Borneol is a colorless, transparent or white translucent flaky crisp crystal; it has a fragrant aroma, pungent and cool taste; it is volatile, easy to sublimate, and produces thick smoke when ignited, and has a light flame.
This product is easily soluble in ethanol, chloroform, gasoline or ether, and almost insoluble in water.
Dextral borneol has a melting point of 208°C and a boiling point of 212°C. L-borneol has a melting point of 204°C and a boiling point of 210°C.
Efficacy of borneol Borneolum is a commonly used traditional Chinese medicine in clinical practice. Based on its functions of refreshing the brain, resuscitating, clearing away heat and relieving pain, antiseptic and promoting muscle growth, modern pharmacological research shows that borneol has a variety of medicinal effects.
1. Easy to penetrate the blood-brain barrier.
Born easily penetrates the blood-brain barrier.
Research shows that borneol can significantly relax the intercellular atretic zonules of the blood-brain barrier, thereby accelerating the intercellular transfer of substances.
2. Promote drug absorption.
①Promote transdermal absorption.
Bornol is an effective transdermal accelerator, which can promote the transdermal absorption of topical corticosteroids, diclofenac and other drugs.
② Promote the penetration of drugs through the cornea and improve the bioavailability of eye drugs.
③ Promote the penetration of drugs through the nasal mucosa, increase the rate of drug absorption into the brain through the nasal cavity, and increase the absorption of drugs in brain tissue. It is a quick-acting way to treat the acute phase of ischemic cerebrovascular insufficiency. .
3. Fight ischemia and damage to the circulatory system.
Bornole is beneficial to the prevention and treatment of coronary spasm and can reduce myocardial damage caused by ischemia.
Experimental findings: Single-flavor borneol has similar effects to Guanxin Suhe Pills on dogs with acute myocardial infarction. It can increase coronary sinus blood flow, slow down the heart rate, and reduce myocardial oxygen consumption.
4. It has a two-way regulatory and protective effect on the central nervous system.
First, it has a two-way regulating effect on the central nervous system.
Bornol has a two-way regulating effect on the excitability of the central nervous system. It can not only "calm and soothe the nerves", but also have a refreshing effect.
The second is the protective effect on the central nervous system.
Bornol also has a protective effect on the brain, which is beneficial to the recovery of cerebral edema, protects secondary damage after cerebral ischemia, and improves impaired awakening ability.
In addition, borneol also promotes the division of glial cells.
5. Antibacterial, anti-inflammatory and analgesic effects.
Natural borneol can significantly inhibit the increase in peritoneal capillary permeability in mice caused by acetic acid, and has an anti-inflammatory effect; it can significantly prolong the pain response time and pain response in mice caused by thermal stimulation, and has an analgesic effect; In vitro direct antiviral tests show that it has the effect of inhibiting influenza viruses.
6. Anti-fertility effect.
Bornole can induce abortion in mid- and late-pregnancy mice, with pregnancy termination rates of 100% and 91% respectively, but has no obvious effect on early pregnancy.
7. Promote wound healing.
Borneol can increase the structure of granulation tissue and regeneration of epidermal cells, repair skin attachments and has a strong wound healing effect.
What is the function of borneol? Rejuvenate the mind, clear away heat and relieve pain.
Borneol is a traditional Chinese medicine. It is borneol processed and synthesized from turpentine, camphor and other raw materials. It is better to have large pieces, white color and pure aroma.
The nature and flavor of borneol are pungent, bitter, and slightly cold, and it returns to the heart, spleen, and lung meridians.
The main functions and effects of borneol are to awaken the mind, clear away heat and relieve pain, and is used to treat febrile coma, convulsions, strokes with phlegm, Qi stagnation, coma, chest pain, chest pain, and red eyes. , aphtha, sore throat, ear canal discharge, etc.
Borneol is a medicine with a spicy smell and a refreshing effect. Its effect is a bit like musk, but its potency is milder than that of musk, so the two medicines are often used in conjunction with each other.
The medicinal properties of borneol are cold and cooling, so it is more suitable for treating heat-induced coma. For example, Sanbao Angong Niuhuang Pills, Zhibaodan and Suhexiang Pills all contain borneol. .
Borneol is a medicine with a spicy fragrance that can open up all the orifices and relieve pain. It can enter the heart meridian to open up the orifices and relieve pain. Therefore, it can be used to treat chest pain and heartache. It can also be used to treat chest pain and pain. Injuries, muscle and bone pain.
In addition, borneol can also be used externally to clear away heat and relieve pain, improve eyesight, reduce nebula, promote muscle growth and reduce ulcers. It can be used to treat red and swollen eyes, sore throat, sores, swollen and painful ulcers, ulcers that have not closed for a long time, and ear canals. Symptoms such as pus discharge.
What does the "borneol" in the medicine do? Other names of borneol: borneol
brain
ruiborneol
plum blossom brain
plum blossom brain
Pian Nao
Meihua Nao
Borneo
Plum slices
Plum ice
The nature and taste of moxa slices Meridians
Punish, bitter, slightly cold.
Guixin, spleen, lung hydrocarbons.
Efficacy
Refreshes the mind, clears away heat and relieves pain.
Application 1, used to treat coma.
This product has the effect of resuscitating and awakening the mind, but it is not as good as musk. The two are often used in conjunction with each other.
However, borneol is cold in nature and is a cooling product. It is suitable for treating coma due to fever, phlegm-heat internal obstruction, syncope due to heat-heat, infantile convulsions and other thermal obstructions. It is often combined with bezoar and musk deer. , Coptis chinensis and other compatibility, such as Angong Niuhuang Pills.
If it is combined with resuscitating drugs that warm the body and dispel cold and have a warmer nature, it can also treat cold syndrome.
2． Used for red and swollen eyes, sore throat, and aphthous ulcers.
This product is bitter and cold, has the effect of clearing away heat, relieving pain and reducing swelling. It is a commonly used medicine in the Department of Otology.
To treat red, swollen and painful eyes, eye drops alone are effective: it can also be combined with calamine, borax, bear bile, etc. to make eye drops, such as Babao eye drops.
To treat sore throat and sores on the mouth and tongue, it is often mixed with borax, cinnabar, and xuanming powder into fine powder, and then blown and applied to the affected area, such as Bingboran powder.
To treat wind-heat throat paralysis, "Binhu Ji Simplified Prescriptions" combine it with rushes, cork, and alum into powder, and blow on the affected area to get the effect.
3. It is used for swelling and pain of sores and ulcers that are not astringent after ulceration.
This product also has heat-clearing, detoxifying, antiseptic and muscle-building effects.
Use this product with cinnabar and sesame oil to make a reddish-brown ointment for external use, which can treat burns; it can be used with elephant skin, dried blood, and frankincense to treat sores and ulcers that are not astringent, such as Shengji Powder .
In modern times, this product is dissolved in walnut oil and dropped into the ears to treat acute and chronic suppurative otitis media, and has a good effect.
In addition, this product is used to treat coronary heart disease, angina pectoris and toothache, and has certain curative effects.
Usage and Dosage
Pulse into powder, 0.03~0.1g each time.
Appropriate amount for external use.
Not suitable for decoction.
Usage precautions
Pregnant women should use with caution.
Experiments have shown that this product can induce labor in mid- and late-term pregnant mice.
Preparation
1. "Newly Revised Materia Medica": "It treats evil spirits in the heart and stomach, accumulation of rheumatism, deafness, improves eyesight, and removes red eyes and skin nebula.
"
"Compendium of Materia Medica": "Cures throat paralysis, Brain pain, flat nose, toothache, typhoid, tongue prolapse, and acne in children.
Opens all the orifices and disperses stagnant fire.
"
"Yilin Compendium": "Borneolumenum mainly disperses stagnant fire, can penetrate bone heat, and treat epilepsy, phlegm, throat numbness, and tongue
< p> Bloating, toothache, deafness, sneezing, red eyes and floating nebula, invagination of pox, insecticide, hemorrhoids, inducing birth, unprotected sex, it can also produce muscle and relieve pain.However, it is scattered and easily exhausted, which means it is ultimately cold.
”
2. Borneolum borneol contains dexborneborneol, as well as terpenes such as rhotropene, β-elemene, caryophyllene, and oleanolic acid. , malic acid, asiatic acid, borneol, cocadiol and other triterpenoid compounds.
Moi tablets contain L-borneol.
The machine-made borneol is a racemic mixture. Borneolum.
Bornol is slightly irritated to sensory nerves when applied locally, and has certain analgesic and mild antiseptic effects.
It is rapidly absorbed through the mesentery and can be passed within 5 minutes of administration. The blood-brain barrier, and the accumulation time in the brain is long and the amount is quite high. This provides preliminary experimental basis for the aromatic resuscitation effect of borneol.
Higher concentration (0.5%) is effective against Staphylococcus aureus and Staphylococcus aureus. Streptococcus, Diococcus pneumoniae, Escherichia coli and some pathogenic skin fungi have inhibitory effects on mid- and late-term pregnant mice.
p>
Bornoleum is a processed product of dipterocarps, a plant of the Dipterocarpaceae family, and its ingredients include dexborneborneol, β-elemene, caryophyllene, etc.
This product has a pungent taste. , cold in nature, has the functions of clearing various orifices, dispersing stagnation of fire, reducing swelling and removing nebula.
It is used in beauty prescriptions to clear away heat and dissipate fire, remove filth and transform turbidity, and is used for blood heat. , treatment of bad breath, body qi, sores, swelling and boils caused by accumulation of internal heat.
3.
Bornole properties:
Bornole is non-toxic. It is a transparent or white translucent flaky crisp crystal; it has a fragrant aroma, pungent and cool taste;
It is volatile, easy to sublimate, and produces thick smoke when ignited.
This product is easily soluble in ethanol, chloroform, gasoline or ether, and almost insoluble in water.
The melting point of dextroborneol is 208°C, the boiling point is 212°C, and the melting point of levoborneol is 204°C. , boiling point 210℃ 4. Quality standard: (2000 edition of Chinese Pharmacopoeia)
Appearance:
Melting point: 205-210℃
Identification:
Vanillin sulfuric acid color reaction
Camphor odor reaction
Check:
PH value: Neither phenolphthalein nor methyl red should appear red.
Non-volatile matter: less than 0.035%
Moisture: Dissolved petroleum ether should be clarified
Heavy metals: no more than 5ppm
Content determination:
Adopt the GC method, use methyl salicylate as the internal standard, and use the borneol standard to calculate the correction factor and measure the sample. The borneol content: not less than 55%.
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