I have had stomach trouble for five years. I have been taking omeprazole, and my condition is well controlled. But I feel sick every time I eat in the last two weeks. Should I change the dressing?
On the Internet, there are many similar situations.
Although omeprazole is the "star" of stomach medicine, can it really be eaten casually? It is a three-point poison of medicine, and only by knowing its contraindications can the medicine exert its greatest curative effect.
Omeprazole belongs to lazole drugs, and its scientific name is also called proton pump inhibitor. Its main function is to inhibit the secretion of gastric acid. Gastric acid is hydrochloric acid secreted in gastric juice. In a certain amount, it can kill bacteria in food, ensure the safety of the stomach, increase protease in the stomach and help the gastrointestinal tract digest food.
But if gastric juice is secreted too much, nausea and sour water will appear. Long-term stimulation of the stomach will cause peptic ulcer, gastroesophageal reflux and other diseases. It can be said that lazole drugs are precisely to prevent gastric acid exuberance. Therefore, omeprazole is only needed in three situations:
1, there is definite damage to gastric mucosa: if gastric acid and pepsin invade gastric mucosa, it will lead to peptic ulcer.
2. There is obvious gastric acid reflux or heartburn: patients often have obvious abdominal pain and heartburn due to esophageal inflammatory lesions caused by reflux of stomach and duodenal contents to the esophagus.
3, prevent serious diseases: such as upper gastrointestinal bleeding caused by stomach surgery.
Many people mention omeprazole, only knowing that it is a famous stomach medicine, and there are many minor stomach problems, which will have an effect once taken. Therefore, many people regard it as a "panacea" for the treatment of gastrointestinal diseases. As long as it is related to the stomach, put it on the top. In fact, any drug has corresponding indications. If you don't choose or take it by mistake for a long time, it will also have side effects and even the risk of cancer.
① Rash
Rash is a common allergic reaction to omeprazole. Patients generally start from the distal extremities and gradually spread to the trunk, face and scalp of the whole body. Generally, the rash will disappear by itself 1~3 days after drug withdrawal.
② Loss of vitamin b 12.
The absorption of vitamin B 12 and folic acid depends on the acidic environment. Excessive inhibition of gastric acid will destroy the environment suitable for vitamins, which will lead to the lack of B vitamins.
③ Digestive system discomfort
Gastrointestinal discomfort is also a common adverse reaction of omeprazole, such as nausea, abdominal pain and flatulence. It usually occurs in the early stage of medication and can be relieved by itself.
④ Fracture
Many studies have shown that long-term use of omeprazole will increase the risk of fracture. When acid is strongly inhibited, the absorption of calcium will also be affected, especially in the case of large dose and long-term use in the elderly, which is easy to aggravate osteoporosis and increase the risk of fracture.
⑤ Causing atrophic gastritis.
Moderate gastric acid can help digestion, kill bacteria in food, ensure the safety of the stomach and increase the activity of pepsin. Excessive gastric acid inhibition, due to insufficient secretion, gastric function gradually weakened, leading to atrophic gastritis.
⑥ May increase the risk of cancer.
Studies have shown that after taking proton pump inhibitor 10 or longer, the risk of intestinal cancer, liver cancer and pancreatic cancer increases. This is also the most serious harm of taking omeprazole for a long time, and it also reminds people from another angle to be alert to the carcinogenicity of omeprazole and not to eat it casually.
According to the above side effects of omeprazole, it can be concluded that people with atrophic gastritis, vitamin B deficiency, dyspepsia, emaciation and osteoporosis should not take omeprazole for a long time.
In addition, patients with renal insufficiency should not take it for a long time. Omeprazole occasionally has side effects such as elevated transaminase, which may aggravate kidney damage.
Compared with adults, infants are weak and immature in all aspects, and taking omeprazole may cause more or more serious side effects. In addition, pregnant women and lactating women should also take it carefully, and it is best to take it according to the doctor's advice.
Xiao's father recently suffered from stomach trouble, and he ran out of omeprazole at home, so Xiao went to a nearby drugstore to buy it, only to find that the prices of different brands varied greatly. One bottle of omeprazole in 5 yuan, and the other one in 95 yuan only sells 8 tablets. He is puzzled: why is the price difference of the same omeprazole so much?
The more expensive omeprazole in the market is not a "black-hearted drug", but actually an imported drug, which is the original research drug, which is the first drug developed and produced in the world. Generally, the original drug needs a lot of manpower and material resources from research and development to listing. Because of the high research and development cost, high risk and many circulation links, the price is often more expensive.
5 yuan's bottle is a generic drug, which is an imitation of the original drug. Patented drugs can be copied after the protection period. Although it is an imitation, it is not a so-called "fake medicine", let alone a "fake medicine". The generic drugs that can be marketed are the same as the original drugs in terms of safety and efficacy, quality, function and indications.
There are some differences between generic drugs and original drugs. For example, generic drugs may be different in shape, color, packaging and labeling, but these do not affect the efficacy and safety. Of course, if economic conditions permit, the original drug is the best. If the economic conditions are average, or if you take medicine for a long time, it is still recommended to choose a cheaper generic drug.
In the treatment of diseases, taking medicine according to doctor's advice is more important than choosing which medicine. Don't add drugs or stop taking drugs without authorization. Your body may not have much feedback at first, but over time, it is likely to bring unnecessary harm to other organs of the body.
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