The vaccines to prevent avian influenza mainly include: 1. Whole virus inactivated vaccine 2. Subunit vaccine 3. Recombinant live vector vaccine, 4. Nucleic acid vaccine 5. Antisense genetic engineering vaccine 6. Express H5 subtype highly pathogenic poultry Recombinant Newcastle disease virus live vector bivalent vaccine based on influenza virus antigen genes. 1. Carry out immunization. Immunization is the most important measure to control the epidemic of avian influenza. There are currently two types of bird flu vaccines: monovalent and bivalent. Since there is usually only one serotype of bird flu circulating in a certain area, it is feasible to grasp the prevailing strains of local epidemics and vaccinate with monovalent vaccines. This can help to accurately Monitor the epidemic. When the serotype is unclear in the area where the disease occurs, 2-3-valent vaccine can be used for immunization. The protection period after vaccine immunization can generally last up to 6 months, but in order to maintain a reliable immune effect, booster vaccination should usually be done every three months. It is recommended that the first dose is 0.3 ml for chickens and laying ducks aged 5-15 days, and 0.5 ml for larger meat ducks and geese, by subcutaneous or intramuscular injection. The second dose is 50-60 days old, 1 ml for meat ducks and geese, and 0.5 ml for chickens and laying ducks. The three exemptions are taken before delivery, 2-3 ml for geese, 1-2 ml for ducks, and 0.5 ml for chickens. Commercial laying poultry and breeding poultry can receive four vaccinations at the age of 40 weeks in the mid-laying period. 2. Treatment: Poultry with highly pathogenic avian influenza should be resolutely culled and eliminated. If avian influenza with medium or low pathogenicity occurs, it can be treated with drugs. (1) Anti-viral: 200g of Green Hutaining for every 300g of drinking water, 400kg or general anti-viral 1+1 injection (plus cephalosporin), one injection is effective. (2) Control secondary infections: When poultry are found to have symptoms similar to avian influenza, antibiotics should be used to control secondary infections as soon as possible. For example, use 50-100PPm enrofloxacin in drinking water for 4-5 days; add 5 grams of oxytetracycline per 100 kilograms of feed, etc. In order to improve the physical fitness and disease resistance of poultry, multi-dimensional electrolytes can be added to the drinking water at the same time. 3. Strengthen comprehensive control measures against avian influenza epidemics (1) Do not introduce or transfer fresh poultry products from epidemic areas or areas where the epidemic situation is unknown. (2) The poultry farm raises a single variety of poultry, does not mix different varieties of poultry or livestock, and implements an "all in, all out" feeding system; the poultry farm and its staff do not raise other livestock and poultry. (3) Control outsiders and vehicles from entering the poultry farm. If entry is really necessary, they must be disinfected. Vehicles transporting feed and poultry products during production should be dedicated separately. (4) Control other animals from carrying poisons. No tall trees should be planted in the poultry farms, and lawns should be used as a green environment as much as possible to prevent the gathering of wild birds; rodent control activities are often carried out, and animals such as pigs, dogs, cats, etc. are not raised in the production areas. Although these animals are currently free of avian influenza diseases , but often poisonous. (5) Prepare your own drinking water system, using deep well water or tap water instead of river, lake, or pond water. Lakes and ponds used for raising ducks and geese should be kept in a fixed water area to prevent wild birds and other livestock from entering. If possible, they should be disinfected regularly. (6) Poultry manure and litter are accumulated, fermented or burned. Stacked fermentation takes no less than 20 days. (7) Do not bring fresh livestock and poultry products from outside into the poultry farm. Poultry workers must wear work clothes, work boots, and masks when going to work, and must change clothes when entering and leaving the poultry farm.