Now people often ask, which is more active, Brother Long or Kang Kuan? Longge is fipronil and Kangkuan is chlorantraniliprole. Among all chemical structural formulas, the total activity of fluoride ion is the highest. Why did Bayer introduce fipronil instead of bromothalonil? The reason is that fipronil has the highest activity and the best effect in the same series. According to this reasoning, it seems that Brother Long is more active than Kang Kuan. But I tell you, Kang Kuan is more active than Brother Long. The reason is that Kang Kuan and Brother Long are not the same substance. Although they have the same insecticidal mechanism and similar structure, they are not the same kind of substances. Kangkuan is called chlorantraniliprole, which belongs to o-formylaminobenzamide pesticide, and Longge is called flubendiamide, which belongs to phthalamide pesticide. It's like a Paralympic champion's performance may not be as good as the sixth place in the 100-meter Olympic Games, and the reason is the same. (But this metaphor is not appropriate. Brother Long is not a Paralympic athlete, and Kang Kuan is not an Olympic athlete. In fact, the gap between the two is very small. A brief review of Kang Kuan's invention process may be more impressive. As mentioned above, in the competition of phthalamide research, Japanese pesticides won the first game and launched the first commercial product fipronil. Almost at the same time, DuPont also invented similar substances, but Japanese pesticides have been patented, and DuPont has no choice but to make persistent efforts. Dupont Company, with fipronil as the forerunner, carried out great transformation on this kind of compound, changed the structure of the compound, and got a new compound called o-formylaminobenzamide. Then it made a lot of improvement, optimization and screening in this new compound, and finally invented the first commercial product Kangkuan in 2000. Therefore, Kang Kuan is actually an improved and upgraded version of Brother Long, and the effect is certainly better than that of Brother Long.