Ibuprofen, also known as "ibuprofen", is a non-steroidal anti-inflammatory drug (NSAID), which is generally used for relieving fever, pain and inflammation. In 1960s, Stuart Adams of Boots Company invented ibuprofen and obtained a patent.
In the 1990s, ibuprofen entered China, and there are two kinds of active ingredients and preparations in the market. In this respect, China Pharmaceutical Factory has super capabilities. The two domestic companies producing ibuprofen are Xinhua Pharmaceutical and Hendi Pharmaceutical respectively.
Development history of ibuprofen
Stuart Adams was born in Northampton, England on 1923. His father is an ordinary railway worker. /kloc-at the age of 0/6, Stuart Adams dropped out of school and worked as an apprentice in a local Bozi pharmacy. Perhaps by fate, the work as a trainee pharmacist became a turning point in his life.
When he was an apprentice at Boots Pharmacy, Stuart Adams found that selling drugs was not his interest, but he was really interested in chemistry and pharmacy. Three years later, with the help of the company, Stewart, who became a pharmacist, successfully entered Nottingham University to study pharmacy and obtained a bachelor's degree. Later, he received a doctorate in pharmacology from Leeds University.
1952, Stewart returned to Boots and became a member of the company's research project. He began to study and found that there was a steroid-like treatment for rheumatoid arthritis, and there were no side effects. Since then, Stewart has embarked on a long journey to explore ibuprofen.
After ten years of research, Stewart's team tested the special effects of more than 600 compounds. Four drugs entered clinical trials, but all failed. Stewart's hangover gave him hope when everyone was desperate.
At that time, Stewart and his members had just synthesized a compound called p-isobutyl phenylpropionic acid. He had a headache after a hangover and tried taking 600 mg, but the effect was unexpectedly good. Excited Stewart and his team immediately continued their research and quickly passed the clinical trial of ibuprofen.
1962, Boots Company registered the patent of ibuprofen. In 1969, ibuprofen was approved as a prescription drug in Britain. From 65438 to 0983, ibuprofen was widely used as an over-the-counter drug in various pharmacies. Since then, ibuprofen has gradually swept the world with its low price and rapid analgesic effect.
Refer to the above content: Baidu Encyclopedia-Ibuprofen