Piglet pullorum (late-onset colibacillosis)
(1) Summary
Also known as late-onset E. coli, it is a common disease in piglets during the lactation period of diarrheal disease. Mainly through digestive tract infection.
It is characterized by the discharge of milky white or off-white smelly and loose feces in sick piglets. The incidence rate is high but the mortality rate is not very high, but the growth rate of the piglets is significantly slowed down.
The cause of the disease is complex and cannot be completely determined. It is generally believed that imbalance of pig intestinal flora and excessive reproduction of Escherichia coli are important causes of this disease. It has been confirmed that porcine rotavirus is one of the pathogens of pullorum in piglets.
This disease mostly occurs in piglets aged 10 to 30 days (the most common disease occurs in piglets aged 10 to 20 days. Within 7 days of age, piglets over 30 days of age rarely develop piglets). There are many factors that induce and aggravate pullorum in piglets, such as improper feeding and management of sows, poor pig house hygiene, varying fat and thin conditions, low milk, large changes in consistency, no seasonality, or sudden cold weather and increased humidity. Heavy weather, rainy weather or poor warmth can all induce the occurrence of pullorum. If the conditions are good and the disease is treated in a timely manner, the disease will be cured quickly and the mortality rate is low. If the conditions are not good, the piglets may become dehydrated, emaciated and die.
(2) Clinical Symptoms
Piglets suddenly have loose stools, which occur one after another in the same litter, and discharge milky white, gray white or light yellowish white, fishy, ??mushy or slurry feces.
The piglets are listless, afraid of cold, dehydrated, eat less or no milk, and sometimes vomit milk.
Generally, the disease of sick pigs is mild and can be cured with timely treatment. However, pigs often become stiff due to repeated attacks. In severe cases, pigs suffer from fecal incontinence and die in about a week.
(3) Pathology
The dead piglets were dehydrated, emaciated, and had pale skin.
The gastric mucosa is congested and edematous, and the intestinal contents are gray-white, sour or mixed with bubbles.
The intestinal wall becomes thin and translucent, the mucosa is congested, bleeding and easily exfoliated, the mesenteric lymph nodes are swollen, and secondary pneumonia lesions are often present.
(4) Prevention and treatment
Comprehensive measures such as antibacterial, antidiarrheal, digestive aid and fluid replenishment should be adopted for the best effect. Choose any one of the following antibacterial drugs.
Antibacterial: 1. Apramycin (also known as: apramycin) is taken orally at a dose of 15 mg/kg body weight every day for 7 days, which can effectively control piglets caused by Escherichia coli. Diarrhea, the effect is better than the control drug neomycin sulfate. Intramuscular injection of "Apramycin sulfate, also known as Shengshengjian powder injection. This drug is more effective.
2. Streptomycin sulfate: intramuscular injection, 10 mg per kg body weight, twice a day;
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3. Ciprofloxacin: Drinking water: 0.01%~0.02%, Mixing: 0.02%~0.04%, Intramuscular injection: 10~15 mg/kg body weight;
4. Norfloxacin: Drinking water: 0.005% ~ 0.01%; Mixing: 0.015% ~ 0.02%; Intramuscular injection: 5 ~ 10 mg/kg body weight;
5. Flufenamphenicol: also known as fluoride Benicol. Intramuscular injection of 20 mg to 30 mg per kilogram of body weight, twice a day, for 3 to 5 days. Oral administration of 20 to 30 mg of body weight per kilogram of body weight, once a day for 3 days. 5 days.
Mixed feeding health prevention dosage: 2% florfenicol premix, add 1 to 2 grams per kg of feed, and double the therapeutic dosage per kg of feed. 4g.
6. Amoxicillin: 10mg per kg body weight once;
7. Xie Li Ting: also called compound amikacin soluble powder, the main ingredient is amikacin. Mix 1 gram of mikacin, isapamicin, hyponitrate (antidiarrheal), scopolamine, etc. per kg of material, and can be used concentratedly once a day for 3 to 5 days;
8. Dysentery King: Chinese medicine. Add 0.75 grams per kg of material.
9. Dysentery: 10 to 15 mg per kilogram of body weight orally, twice a day for 2 to 3 days;
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10. Gentamicin sulfate is taken orally at 5 to 10 mg/kg body weight each time, twice a day for 2 to 3 days.
Attachment: ①Antidiarrhea: tannic acid protein < /p>
② To aid digestion and absorption: take raw materials, baking soda, pepsin, etc.
③ Rehydration: Oral glucose saline and multivitamin formula: add glucose 20 to 1000ml of water. grams, 3.5 grams of sodium chloride, 1.5 grams of potassium chloride, and 2.5 grams of sodium bicarbonate.
4. Prevention: Vaccines have poor preventive effect.