What is dhea? Is dhea coenzyme q 10 useful for premature ovarian failure?

DHEA is dehydroepiandrosterone. Its main functions are anti-aging and synthesis of protein. As a health product, it is mainly used for:

1, which has the function of maintaining ovaries, promoting the development of female follicles and improving the quality of follicles;

2. It can regulate the endocrine function of ovary, and prevent and improve endocrine dysfunction;

3. It can promote ovulation in women's ovaries and improve women's fertility.

4, can improve physical fitness, enhance disease resistance, improve sleep, and regulate bad emotions;

5. It can improve the quality of women's sexual life and increase sexual pleasure;

6, can promote body fat metabolism, and has a certain auxiliary effect on weight loss. Hu (hanyu pinyin)

Side effects of dehydroepiandrosterone:

1, taking DHEA may increase the production of male hormones, so women are prone to signs of masculinity, such as hair loss, deeper voice and acne on their faces.

2. Supplementing too much DHEA will lead to palpitation or excessive secretion of sebaceous glands.

3. Because DHEA can stimulate the secretion of growth hormone, and too much growth hormone will lead to the formation of cancer cells in the human body, too much DHEA in the body may also cause cancer.

4.DHEA will also increase the risk of prostate cancer, breast cancer and uterine cancer, and even make these hormone-sensitive cancer cells more active and worse.

5. After menopause, women usually take hormone therapy to maintain hormone balance in the body. If you take this anti-aging pill, the hormones in your body will increase, which will greatly increase your risk of breast cancer.

6. Excessive use of DHEA by men may also lead to testicular atrophy's disease, male baldness, hypertension or testosterone-related cancer.

Due to the side effects of dehydroepiandrosterone, all dhea in North America and Europe have been removed from the shelves. DHEAAMH, a derivative of 2065 438+00 DHEA, was newly developed in Europe and America, and France presented a more convincing research report. It has been proved that DHEAAMH not only supplements DHEA and prevents its genetic variation, but also plays a significant role in improving the quality of ovaries, follicles and eggs. DHEA AMH completely replaced DHEA.

Compound pregnancy repair factor DHEAAMH- premature ovarian failure improvement system

Premature ovarian failure improvement system-providing backup guarantee for oocyte quality

Significance analysis of DHEA AMH: DHEA balances the hormone level of the pre-pregnancy mother, and AMH increases the egg reserve function.

In this survey, the infertility rate of premature ovarian failure and abnormal ovarian function is 0. 1%, but the clinical manifestations of premature ovarian failure are high FSH level and amenorrhea. The occurrence of premature ovarian failure seriously affects women's psychological state and fertility, causes endocrine disorders, and greatly reduces the probability of pregnancy.

When a woman is born, there are about 2 million follicles in the ovary, but only 400-500 follicles eventually mature, and most of them will die with age. The phenomenon is the decline of ovarian function, the disappearance of ovulation function and the decline of fertility function. Normal women have 65,438+02% eggs in their ovaries at the age of 30, but only 3% eggs remain at the age of 40. In addition to the function of the egg itself will decline with age, when women approach menopause, the menstrual cycle will become more disordered, and the endometrium will become thinner, which is even less suitable for fertilized eggs to implant. At the same time, vaginal discharge is reduced and vagina is dry, which is not conducive to the entry of sperm.

The relationship between DHEAAMH and ovarian microenvironment is indisputable. With the increase of age, the number of remaining follicles decreases. According to traditional theory, the quality of oocytes will also decline at the same time. However, the role of dehydroepiandrosterone questioned this traditional theory. According to this study, although young patients with ovarian dysfunction also showed signs of ovarian aging, their embryo aneuploidy did not increase. The addition of DHEAAMH can significantly reduce the age-related embryo aneuploidy, indicating that the resting eggs mother cells in the ovaries of young patients with ovarian dysfunction are not really aging. The increase of aneuploidy in some women may be due to the lack of DHEAAMH, and the other part may be due to the lack of some unknown key components in normal ovarian environment.

Using DHEAAMH alone or in combination with other hormones will increase women's response to ovulation induction, and measuring DHEAAMH through oocyte and embryo yield may be an auxiliary means to induce ovulation. Before optionally starting gonadotropin therapy, oral administration of DHEAAMH for at least about 65 0 months, preferably about 4 months, can prepare for gonadotropin stimulation of the ovary. At least 4 months before the test tube cycle, gonadotropin combined with dehydroepiandrosterone can obtain a greater response.

Clinical data provide evidence that DHEAAMH supplementation can improve the natural pregnancy rate, in vitro pregnancy rate and cumulative pregnancy rate, and shorten the pregnancy interval. What is dhea? Is dhea coenzyme q 10 useful for premature ovarian failure? )

Irregular menstruation is an important symptom of premature ovarian failure.

I often hear patients say, "doctor, I haven't had my period for a long time." 」

Some menopausal conditions are not very serious, and it is enough to recuperate the body through some diagnosis and treatment methods; In some cases, it is more serious, similar to menopause.

Many of these "menopausal" women are under 40 years old, but they already have the menopausal state that women are usually around 50 years old. Because an important diagnostic index of premature ovarian failure is menopause, it also shows that many of them have a serious decline in ovarian function.

The decline of ovarian function will not only lead to menopause, but also lead to these situations:

Yellow face, flabby skin and bloated figure;

Infertility and anovulation;

Vulvar atrophy, breast atrophy, decreased secretion, vaginal dryness;

Loss of libido, sexual pain, uterine prolapse;

Climacteric syndrome, hot flashes, night sweats, anxiety and alopecia;

The risk of osteoporosis and cardiovascular and cerebrovascular diseases is increased.

……

If you have the above situation, it means that your ovarian function may have been declining. Although the decline of ovarian function is inevitable, if you are under 40 years old, it may be premature ovarian failure, which needs to be diagnosed with the help of a doctor.

Premature ovarian failure not only affects fertility problems.

Many girls always feel incredible after being diagnosed with premature ovarian failure. Some said, "I'm only in my twenties. I'm not married. How can I have premature ovarian failure? " Hearing these words, my heart will always be heavy, because the trend of premature ovarian failure in women is getting younger and younger.

Premature ovarian failure has a great influence on our health, one of which is to reduce the possibility of having children. Therefore, I often say to women who are diagnosed with fertility needs, "If you are married, if you have fertility requirements, try to have children as early as possible, and the later you have children, the less likely you are. 」

For some girls, they said, "I can accept Dink, and it doesn't matter if ovarian function declines." Can we stop the treatment? " 」

My answer is: "No! 」

This is because premature ovarian failure not only has an impact on fertility, but also has a great impact on your health. It will lower your estrogen level, and the most important hormone for women is estrogen. It can be said that it is with it that the girls are beautiful and moving.

If the estrogen level in the body is abnormally reduced, it may accelerate the aging of women. At the same time, you will have symptoms of "menopause" earlier than your peers, including hot flashes, sweating and bad temper.

And suffering from premature ovarian failure will make you more prone to osteoporosis than your peers, because your bone density is declining; ?

Also, your risk of cardiovascular disease will greatly increase.

When you hear this, you don't have to be too alarmed. Although the harm of premature ovarian failure is not small, it can be treated to some extent as long as you learn to treat premature ovarian failure correctly and seek the help of professional doctors. Anxiety and panic will not help the treatment of premature ovarian failure, and even delay the diagnosis and treatment.

For example, some girls think it is premature ovarian failure because they don't understand and see that their menstruation is somewhat disordered. In desperation, I sought medical advice everywhere. At this time, I saw health care products and medicines for the treatment of premature ovarian failure, as well as various massagers and treatment and maintenance projects. No matter whether the hospital is formal or not, whether the treatment method is appropriate or not, and whether it is harmful to the body, I tried it without judgment, so that I stepped on many pits and paid a lot of "IQ tax". Instead of being optimistic about my illness, I spent a lot of money.

Therefore, the correct attitude towards premature ovarian failure is that we should not only pay attention to it, but also learn to manage it correctly with the help of professional doctors in regular hospitals to minimize its influence and harm to us. What is dhea? Is dhea coenzyme q 10 useful for premature ovarian failure? )

Pay attention to ovarian function, scientific and healthy management.

The maintenance of ovaries, in addition to regular gynecological examinations to eliminate diseases, daily attention to some details can also protect the ovaries.

Appropriate supplementation of estrogen

This is only suitable for women with special needs and needs to be taken under the guidance of a doctor.

There are many adverse reactions caused by estrogen supplementation alone, so DHEAAMH will be used to assist estrogen in Europe. DHEAAMH is an energy factor with more than 30 patents, which can intensively and urgently raise eggs, nest and other fertility problems. In Europe, it is considered as an energy source to assist pregnancy. Britain, Germany and many other European countries have done a lot of research on DHEAAMH. At present, DHEA AMH in China is mostly imported from abroad. In recent years, the application of dehydroepiandrosterone in patients with ovarian dysfunction has been recognized by many countries. According to the survey, about13 fertility centers around the world began to add DHEAAMH to patients with ovarian dysfunction.

In recent years, foreign studies have found that DHEA AMH can repair ovaries, provide ovarian nutrition, improve ovarian reserve function, reduce chromosome aneuploidy, improve embryo quality, reduce abortion rate and cycle cancellation rate, thus improving clinical pregnancy rate.

In the randomized controlled study of DHEA AMH, on the basis of promoting excretion, 65 patients who took DHEA AMH were taken as the study group, and 48 patients who did not take DHEA AMH were taken as the control group. The study group was given DHEA AMH (French ACMETEA, 13g/ bag) 13g/ time, twice a day, and the basic endocrine was checked once a month. If they feel unwell, they can stop taking DHEA AMH and continue to use it after normal.

All patients in the study group received DHEA AMH treatment for 3 months when they entered the cycle. Basic endocrine was measured on the third day of menstruation before and after taking it, and the number of follicles in bilateral ovarian sinuses was counted by B-ultrasound. After entering the cycle, HCG was injected according to the routine test tube. When the dominant follicle was > > 18mm, the eggs were taken 36 hours later, fertilized 4 hours later and fertilized 20 hours later.

After taking DHEA AMH, the basic FSH decreased significantly and the basic AFC increased significantly. AFC is one of the accurate and reliable functional indexes of ovarian reserve. Experimental data show that DHEA AMH can increase the number of fertilized oocytes and embryos in patients with ovarian dysfunction and improve the quality of oocytes and embryos. The results of this study, combined with many studies at home and abroad, show that DHEA AMH can provide essential nutrients for ovaries, repair ovaries, improve ovarian reserve function and improve embryo quality, thus improving the pregnancy outcome of IVF.

When DHEAAMH can't be used, scholars have to use large doses of ovulation-promoting drugs to superovulate. In most cases, the cost is high and the response is low, and the clinical effect is uncertain. It has been recognized that the number of ovulation and pregnancy rate can be increased by using dehydroepiandrosterone.

Keep a regular life.

Pay attention to the combination of work and rest to ensure adequate sleep. Learn to release pressure, maintain a good attitude and cheerful and optimistic personality.

Regulate diet

Pay attention to the nutritional balance in the diet. In addition to adequate intake of protein, fat and sugar should also be moderate. At the same time, special attention should be paid to supplementing vitamins E and B2 and minerals such as iron and calcium.

by oneself

Exercise can promote metabolism and blood circulation, and delay organ aging, such as walking, jogging and playing Tai Ji Chuan.

Maintain a harmonious sex life

Harmonious sexual life can enhance people's confidence in life, make people feel happy, reduce psychological pressure, and be good for ovarian function and endocrine.

Shengwa

School-age childbearing is beneficial to women. During pregnancy and postpartum, women's ovaries will be rested and adjusted for ten months or more.

If menstruation is less than ten times and eggs are less than ten times, menopause will be postponed. What is dhea? Is dhea coenzyme q 10 useful for premature ovarian failure? )