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Application number: 991632.3 Application date: April 29, 1999
Loading in the picture Abstract: A hedgehog conjugate, Characterized by comprising * * * valence connected to hedgehog-like protein: a) a polypeptide consisting of 1 to 3 hydrophobic amino acids and/or amino acids capable of forming a transmembrane spiral structure and being positively charged, b) 1 to 4 saturated or unsaturated aliphatic hydrocarbon groups with a chain length of 8 to 24 carbon atoms and hydrophobic effect, or c) a hydrophobic sulfhydryl compound. The activity of that hedgehog-like protein conjugate is improve several times, and the hedgehog-like protein conjugate is suitable for use as a medicament. Applicant: Roche Diagnostics Co., Ltd. Address: Inventor (Designer) in Mannheim, Federal Republic of Germany: A. Eswin K. Lang P. Luger T. Setter Main classification number: C7K19/ Classification number: C7K19/C7K14/435C121/A61k38/17.