1. Research Topic
The Application of Nanotechnology in Biomedicine
(The Application of Nanotechnology in Biomedicine)
2. Research significance
Nanotechnology is a comprehensive research system that prepares, researches and industrializes substances at the nanoscale, and uses nanoscale substances for cross-research and industrialization. It is formed by combining nanotechnology and biology Nanobiology will be an important part of life sciences in the 21st century; nanomedicine formed by the combination of nanotechnology and medicine will certainly greatly improve medical methods and improve treatment levels; nanotechnology, known as the manufacturing technology of the 21st century, will allow us to It also allows us to create some tools that are much smaller than cells. Using these tools, we can more conveniently explore the mysteries of life, enable medical treatment at the cellular and molecular levels, and enable us to We examine biological tissues and organs in incredible detail. Nanotechnology has broad development prospects in the field of biomedicine.
3. Subject background related to the topic
Research started in the 1980s Nanotechnology achieved breakthrough progress in the 1990s. The integration of nanotechnology with biochemistry and molecular biology will have a profound impact on biomedicine in the 21st century.
Nanotechnology has become a key technology in the 21st century One, it is of extremely important significance to the scientific and technological progress in various fields. Existing research has shown that nanotechnology can be applied to medicine, pharmacy, biology, chemistry and information technology. The penetration of nanotechnology into medicine, bioengineering and pharmacy The impact is obvious. Nanorobots are the most tempting application of nanotechnology in the medical field. They can act as miniature doctors in biomedical engineering and solve problems that are difficult for doctors to solve with traditional technologies. The role of nanotechnology in medicine Important applications - Drug nano-controlled release systems have been widely studied as new drug delivery systems, especially in the fields of targeted and localized drug delivery, mucosal absorption drug delivery, gene therapy and protein and peptide controlled release. Nanoparticles have irreplaceable advantages.
IV. Search database and search scope
1. Search database:
(1) Chinese Journal Full-text Database (entered from 202.115.61.21)
(2) Chongqing VIP Chinese Science and Technology Journal Database (accessed from 202.115.61.21)
(3) Wanfang Database (entered from 202.115.61.21)
( 4) Cambridge Science Abstracts (entered from 202.115.61.21)
(5) American Engineering Index (entered from 202.115.61.21)
2, search scope:
Database name
Search scope
Search type
China Journal Full-text Database
1994-2003
Journal Literature
Chongqing VIP Chinese Science and Technology Journal Database
1989-2003
Journal Literature
Wanfang Database
Before 2003
Journal Literature
Cambridge Science Abstracts
1980-2003
Journal and Conference Literature
American Engineering Index
1990-2003
Journals and Conference Literature
5. Keywords
1. Nanotechnology (nanotechnology); 2. Biomedicine; 3. Application
6. Search formula
1, (T=1)*(K=2)
2, (T=1)*(T=2)*(K=3)
3, (U=1)*(T=2
)
4, (T=1)*(U=2)*(k=3)
Seven, search results
(1) Chinese journals Internet thematic full-text database
1. Use search formula 1 to hit 22 documents, and select 5 articles as follows:
2. Use search formula 2 to hit 10 documents, and select 5 articles as follows:
(2) Chongqing VIP Chinese Science and Technology Journal Database
1. Use search formula 1 to hit 16 documents, and select 5 articles as follows:
2. Use search Formula 2 hits 4 documents, and 4 are selected as follows:
(3) Wanfang Database
1. Search formula 3 is used to hit 7 documents, and 5 are selected as follows:
(3) Wanfang Database
1. p>
2. Use search formula 1 to hit 2 documents. Select 2 articles as follows:
(4) Cambridge Science Abstracts
1. Use search formula 1 to hit 28 documents. Articles, select 5 articles as follows:
2. Use search formula 3 to hit 48 documents, select 5 articles as follows:
(5) American Engineering Index
1. Use search formula 1 to hit 9 documents, and select 5 documents as follows:
2. Use search formula 3 to hit 9 documents, and select 5 documents as follows:
8. Search results Evaluation:
In the Chinese full-text journal database, search formula 1 was used to hit 22 documents, and search formula 2 was used to hit 10 documents; in VIP China Science and Technology Journal Full-text Database, search formula 1 was used to hit 16 documents. , using search formula 2 to hit 4 documents; in Wanfang database, using search formula 3 to hit 7 documents, and using search formula 1 to hit 2 documents; in the Cambridge Science Abstracts database, using search formula 1 to hit 28 documents, and using search formula 3 to hit 28 documents There are 48 documents; the American Engineering Index uses the search formula 1*** to hit 9 documents, and the search formula 3*** to hit 9 documents.
Search fields and search technology play a big role in the retrieval effect Function. First of all, the search scope must be correctly selected; secondly, the search field must be correctly selected. For search terms with high specificity, you can use the title field and keyword field. For search terms with low specificity, you can use any field. In terms of search technology, you can use Truncating characters prevent missed detections and improve the detection rate; use adjacent search technology to improve the detection rate and detection rate, etc. From the perspective of search fields, using the title field to search has a higher accuracy rate than using other fields to search , more in line with the requirements of the subject; when the retrieved document information is relatively small, it is best to use any field (also called a full-text field).
China Journal Network full-text database, VIP Chinese Science and Technology Journal Database accuracy rate, The retrieval rate is high, and almost all full texts are provided for free, and online printing is provided. Both databases can download bibliographies, among which VIP can choose to download the current record, marked records, and all records. VIP has collected records from 1989 to There are 12,000 journals in 2002, and the 5,300 journals collected by China Periodicals Network are from 1994 to 2002. The VIP search results cannot choose the sorting method, while the search results of China Periodicals Network have three sorting methods: disorder, relevance, and update date. Available to choose from. China Journal Network provides initial and advanced search methods. VIP provides same field combination search and transformed field advanced search. In terms of word meaning specifications, VIP has a synonym thesaurus and the same author thesaurus. China Periodical Network A word list function is provided to help users correctly select search terms and improve the compatibility of search terms with the database, thus ensuring the search results.
9. Overview:
Nano Technology (Nanoscale technology) is a science and technology that manipulates atoms and molecules within the spatial scale of 01-100nm, processes materials, manufactures products with specific functions, or studies a certain substance to master the movement patterns and characteristics of its atoms and molecules. Technical disciplines. The field of nanotechnology not only includes nanoelectronics, nanomaterials, nanomanufacturing, nanobiology, nanomicroscopy and nanomachining technology, but is also a multi-disciplinary cross-sectional discipline. It is in modern physics, Born on the basis of the combination of chemistry and advanced engineering technology, it is a new science and technology closely integrated with high technology. Biomedical engineering is a modern life science and medical technology.
A fringe discipline developed by combining science and engineering. [004]
Nanotechnology, which was studied in the 1980s, achieved breakthrough progress in the 1990s. [018] Nanotechnology and biochemistry, molecular biology The integration of science and technology will have a profound impact on biomedicine in the 21st century.[026]
Nanotechnology has become one of the key technologies in the 21st century and is of extremely important significance to scientific and technological progress in various fields. Already Research shows that nanotechnology can be applied to medicine, pharmacy, biology, chemistry and information technology. The penetration and impact of nanotechnology on medicine, bioengineering and pharmacy are obvious. Nanorobots are the application of nanotechnology in the medical field. The most tempting content is that it can act as a miniature doctor in biomedical engineering, solving problems that are difficult for doctors to solve with traditional technology. The important application of nanotechnology in medicine - drug nanocontrolled release system has been widely studied as a new drug delivery system. , especially in the fields of targeted and localized drug delivery, mucosal absorption drug delivery, gene therapy and controlled release of proteins and peptides, nanoparticles have irreplaceable advantages.[015]
Nanotechnology and biology The combination of nanobiology will be an important part of life sciences in the 21st century; nanomedicine formed by the combination of nanotechnology and medicine will greatly improve medical methods and improve treatment levels; nanotechnology is known as the manufacturing technology of the 21st century It will allow us to manufacture some complex molecular machines cheaply, and it will also allow us to create some tools that are much smaller than cells. Using these tools, we can more conveniently explore the mysteries of life. It will allow medical treatment to be carried out at the cellular and molecular level. .It also allows us to examine biological tissues and organs with incredible details.[012]
A review of the research progress of international and domestic nanotechnology in the field of biomedical engineering in recent years shows that: in the field of pharmaceuticals, nanotechnology Technology and nanomaterials play an important role in improving the bioavailability of drugs, controlling release systems, improving the targeting of drug effects, and establishing new drug administration routes. These studies have brought new perspectives to the modern research of traditional Chinese medicine. Hope.[010]
One of the core development directions of the application of nanoscience and technology is its research and development in life sciences and human health care. At present, nanofunctional materials and devices are not only used in biological In addition to the application and development research of macromolecules, such as DNA, RNA, and protein molecular structure and function detection, it is particularly important to form a large number of applicable technologies in the medical field, mainly including: nanomaterials and technology in nanomedicine Applications in systems, nanomaterial labeling and single molecule detection technology, applications of nanomaterials and devices in medical clinical diagnosis and treatment of major diseases, applications of nanomaterials and rehabilitation equipment and artificial organs, etc., in the main aspects of biomedical nanotechnology Based on the summary of applied research.[011]
Nano science and technology is a focus of scientific and technological development in the world today. Nanotechnology and nanomaterials have broad prospects in biological environmental protection and biomedical applications, and It will have a profound impact. [008] The strategic position of nanotechnology in the scientific and technological revolution of the 21st century. The broad application prospects of nanotechnology in many fields such as electronics and information, biomedicine, military and aerospace will surely promote the new development of the 21st century. The arrival of the industrial revolution.[003]
10. Learning experience
The 21st century is the age of information. Obtaining information quickly and effectively from the vast ocean of knowledge is an important task for everyone. It is an important technology that modern people should and must master. In particular, we college students should strive to improve their ability to use information to analyze and solve problems. Through the study of the "Scientific and Technological Information Retrieval" course in this period, I have mastered the domestic technology more skillfully. Retrieval methods and techniques for foreign journal literature information and patent literature information. Learned to use Boolean retrieval, lexeme retrieval, truncation retrieval and restricted retrieval and other retrieval techniques to write computer search formulas, so as to quickly and accurately retrieve literature information. And initially I learned how to process and organize the retrieved information. In the practice of retrieval, I personally experienced the unique advantages and disadvantages of various information databases at home and abroad, mastered certain retrieval skills, and learned that the choice of search terms will affect the recall rate. Search field selection
It will affect the accuracy rate, and the combination of search terms will directly affect the retrieval efficiency. Through the comprehensive report, I learned to analyze and synthesize the information in hand, and based on the existing information retrieved, I came to the current situation at home and abroad. Research trends in one direction can be used to figure out the research direction that should be started, and avoid starting over from work that others have already done. Moreover, you can obtain relevant content about the research direction you want by searching domestic and foreign academic papers and patents, and bring the results. Use it for reference instead of starting from scratch to save time and energy. In short, this course provides very important research methods and is an indispensable preparation tool for scientific research. Study this course well and prepare yourself for completing graduation thesis and graduate thesis in the future. And laid a solid foundation for future scientific research work. In the process of making comprehensive reports, I encountered many problems. Through careful thinking, repeated experiments and communication with classmates, all the problems were solved, and I learned a lot from them. My own thinking, collaboration skills and problem-solving methods have made me make progress again.