Pharmacological and Toxicological Studies on 7- hydroxy -4- methylcoumarin Tablets

7- hydroxy -4- methyl coumarin is a coumarin derivative, which can relax Oddi sphincter and has a strong spasmolytic and analgesic effect. At the same time, it can gently and continuously promote bile secretion, strengthen gallbladder contraction and bacteriostasis, and has obvious choledocholithiasis effect, which is beneficial to the discharge of stones and has certain choledocholithiasis effect. Some patients with elevated alanine aminotransferase returned to normal with the elimination of inflammation after taking the medicine. The toxicity of this product is low, and the acute toxicity LD50 of mice is 5375mg/kg.