Hello, I want to ask, if this patent has an agency, must the agency change the patentee?

Yes, if there is an entrusted agency, the agency will handle all the agency matters.

If you need to handle it yourself, you should also submit a statement of cancellation of entrustment when submitting the change of the project for record.

If another agency is needed, another agency needs to submit a statement for filing project changes, cancellation of entrustment and new power of attorney.