What does cross-regional jurisdiction of intellectual property courts mean?

It is a case involving cross-administrative division jurisdiction.

For example, the Guangzhou Intellectual Property Court not only has jurisdiction over intellectual property cases in Guangzhou, but also cross-region jurisdiction over patents, new plant varieties, and integrated circuits within Guangdong Province (except Shenzhen City). First-instance civil and administrative cases on intellectual property rights involving layout designs, technical secrets, and computer software; first-instance civil cases involving cross-regional jurisdiction involving the recognition of well-known trademarks.