What is motor neuron disease?

Motor neuron disease is a neurodegenerative disease or neurodegenerative disease, which is a state of decrease and apoptosis of motor neurons with unknown reasons. Motor cells are divided into two types, one is cortical cells, mainly cells in frontal cortex. The second is the motor cells of the spinal cord, mainly the cells in the anterior horn and lateral horn of the spinal cord. The most obvious symptom after the occurrence is weakness. Muscle pulsation and progressive atrophy can occur, and the lesions are uneven. Therefore, in the early stage or development stage, the lesions of different limbs may be inconsistent, which may be that the upper limbs are heavy and the lower limbs are light, and the final result is muscle atrophy. Divided into several types. One is a typical motor neuron disease, including cortex, brain stem and spinal cord. All motor neurons have no pathological changes, and patients will have limb weakness, paralysis and inability to swallow. There is also a kind of muscle atrophy called spinal muscular atrophy, which only affects the muscles and motor neurons of the spinal cord, mainly manifested as muscle weakness and muscle atrophy in limbs. This atrophy is inconsistent with pathological changes and is related to the segments of the spinal cord. The second type is called medullary atrophy, which mainly occurs in medullary cells and can cause dyspnea and dysarthria. If it affects the vertebral bundle, it can also cause a certain degree of motor neuron paralysis on the limbs. In addition, the cortex only involves the cerebral hemisphere or vertebral body bundle, and symptoms of upper neuron paralysis and limb pseudobulbar paralysis may occur. Go to the hospital for further identification.