What are the treatments for pemphigus erythematosus?

1. Corticosteroids: Mainly use Prednisolone or Prednisone (Prednisone) 40-60mg/day. You can also use hydrocortisone 300mg intravenously depending on the condition. After the condition is controlled, Have a planned slow tapering. Up to prednisolone or prednisone 10-15mg/day maintenance dose.

2. Immunosuppressant: Mainly use cyclophosphamide 100mg/day (about 2mg per kilogram), and gradually reduce the dose to zero after the condition stabilizes. Or azathioprine 50mg/2 times/day.

3. Gold therapy: This therapy can be used as a complementary therapy for problems that are difficult to treat with general therapy, especially for mucosal erosion that cannot be cured after a long period of treatment. The main usage of Goldthioglucose is intramuscular injection once a week or every other day, and the dosage is gradually increased. 10mg once in the 1st → 4th week. 25mg once every 5th to 8th week. 9th → 50mg once in the 12th week → 50mg once after the 13th week. The total amount can be up to 1000mg.

4. Plasmapheresis: The purpose of this therapy is to remove abnormal protein components, especially antibodies and immune complexes, and other harmful non-diffusible substances in the patient's plasma, and replace them with those of healthy people. Fresh plasma, fresh frozen plasma or albumin preparation, this method is a complementary therapy for patients with side effects caused by corticosteroids. 1000ml/day, 3 consecutive days as one course of treatment, 1 course of treatment per week, 3 consecutive courses of treatment.