The correct way to take dhea, the role and efficacy of dheaamh
(The correct way to take dhea, the role and efficacy of dheaamh) #ming
The correct way to take dhea
Those who can ask this question must be friends who have already understood the side effects of dhea. There is data showing that large doses of DHEA can cause the growth of peroxisomes in liver cells of experimental animals. Studies have found that this may be due to the fat in the mitochondrial membrane lipids. It is caused by excessive free radicals produced by excessive acyl-coenzyme concentration or excessive respiratory function, causing oxidative damage to the mitochondrial membrane. Since peroxisome proliferating agents often have carcinogenic activity, it is suspected that DHEA may have carcinogenic activity.
There is data showing that large doses of DHEA can cause a variety of uncertain side effects, so its safety needs further evaluation. Especially for women of childbearing age, some scholars are currently trying to maintain its physiological functions and reduce its side effects by changing the molecular structure of DHEA. This aspect is also worthy of further research.
So we have no way of knowing the above dosage, whether it is a single dose or a cumulative dose taken over a long period of time, and we are afraid that it will be useless if we take less, so most of the DHEA says 25mg and 50mg. How to choose?
In fact, this issue was something we had to struggle with in the 1990s. It was no longer necessary until the United States and Europe stopped producing and selling DHEA. It was not because it was unavailable, but because Europe and the United States introduced new products in 2010. The derivative of DHEA, DHEAAMH, was developed, and France presented a more convincing research report. DHEAAMH was verified to supplement DHEA, prevent the genetic variation caused by DHEA, and significantly improve the quality of ovaries, follicles, and eggs. effect.
To avoid side effects, how to take DHEAAMH?
Clinical verification: 160 patients with ovarian function who were unable to have babies, aged 28 to 45 (40.71 ±3. 14) years old, and BMI 18.5 to 23.9 (21.73 ±1.34).
The patients were randomly divided into 55 cases in the combination group, 57 cases in the DHEAAMH group, and 48 cases in the vitamin E group
1. Treatment method combination group: oral administration of DHEAAMH (French ACMETEA company) 13 g /time, 3 times/day, vitamin E 10 mg/time, 3 times/day, for 2 menstrual cycles;
2. DHEAAMH group: DHEAAMH is taken orally 13 g/time, 3 times/day, for continuous use 2 menstrual cycles;
3. Vitamin E group: Oral vitamin E 10 mg/time, 3 times/day, for 2 menstrual cycles.
After 2 menstrual cycles of treatment, the ovulation induction program in a high progesterone state was also used.
Results: Ovarian reserve-related indicators in the three groups before and after treatment
Reduced ovarian reserve function is the main reason for pregnancy difficulties in women over 28 years old. It has been observed that DHEAAMH can increase the quantity and quality of oocytes and embryos, increase ovarian function, reduce the pregnancy rate of patients, and reduce the risk of miscarriage; it can increase the rate of high-quality embryos and AMH levels in patients with normal ovarian reserve, and improve pregnancy outcomes.
The double-blind randomized controlled study found that there was no significant change in ovarian AFC between those who supplemented and did not supplement DHEAAMH, but the number of high-quality embryos increased significantly. The reason may be that DHEAAMH can reduce embryonic aneuploidy. After DHEAAMH intervention, the number of primordial follicles, primary follicles, and secondary follicles increased significantly, and the follicular atresia improved.
Studies have shown that DHEAAMH can increase the expression of granulosa cell proliferation markers and the levels of preantral follicles and early follicular phases, promote folliculogenesis, and increase the number of retrieved eggs and oocyte quality. As a component of the extracellular matrix, adhesion protein can reflect the function of cells to a certain extent. DHEAAMH may increase the number of follicles in older women by inhibiting follicular apoptosis and slowing down the decrease in adhesion protein levels.
(The correct way to take dhea, the role and efficacy of dheaamh
Facing this business opportunity, in the early 20th century, the U.S. FDA classified the research results of DHEAAMH as "top secrets for strict blockade in developing countries". "Scientific and technological achievements", DHEAAMH is different from simple DHEA, but has gathered more than 30 patented energy factors. They can intensively and urgently raise eggs, raise nests and other energy factors to maintain fertility problems. It is considered an energy factor in Europe. As a source of energy for assisted pregnancy, the UK, Germany and many other European countries have done a lot of research on DHEAAMH. At present, most of our country's DHEAAMH is imported from abroad. In recent years, the use of DHEAAMH for patients with ovarian insufficiency has been recognized by many countries. According to The survey found that about 1/3 of the fertility centers around the world have begun to add DHEAAMH to patients with low ovarian function. When DHEAAMH cannot be used, scholars have to use high-dose ovulation induction drugs to super-stimulate ovulation. In most cases, this is the case. The cost is high and the response is low, and the clinical effect is uncertain. However, it has been recognized that the application of DHEAAMH can increase the number of ovulation and improve the pregnancy rate.
(The correct method of taking dhea, the role and efficacy of dheaamh)
< p>DHEAAMH: It is recommended to take it from 8 pm to about 2 am the next morning. The blood concentration level will reach the highest 20 minutes after taking it, and the metabolic decline period lasts for more than 7 hours. After 10 pm, the body’s cell metabolism and cell proliferation will occur. During this optimal period, when self-repair is at its strongest, if DHEAAMH can be supplemented to provide nutrients to the body, the body's absorption and utilization rate of DHEAAMH will be high, so it is good to take it before going to bed.In addition, it can be combined with coenzyme Q10: Coenzyme Q10 is a fat-soluble nutrient, and its digestion and absorption require the participation of fat, so it is recommended to take it half an hour after a meal. Normally, within 30 minutes of digestion after a meal, the bile acids in the duodenum are released. The sharp increase in concentration is conducive to the full emulsification of coenzyme Q10 and bile salts, improving absorption rate.
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3. The following are the patent certifications obtained by DHEAAMH
European Food Quality Management Agency (EDQM), EFSA European Food Safety Authority, Det Norske Veritas (DNV) ISO9001 and HACCP quality system, French European Union quality certification, multiple countries and multiple institutions have certified, and the DHEAAMH research and development patents are issued as follows:
Product composition patent FX 4R]
Rousselot SAS Poudre de pepetide collangme #
Rousselot France SAS, Powder of collagen pepetide HSR t
ISO 9001 and HACCP Quality System Certificates issued by Det Norske Veritas (DNV) Issued by Det Norske Veritas (DNV) ISO 9001 and HACCP quality system certificate DQM Certificate issued by European Directorate for the Quality of Medicine (EDQM) European Food Import Registration (in accordance with European Council Resolution 2001/556/ EC) OEЛL ( tE9 EU Food
2001/556/ECIXR ) UNITIKA LTD., Ceramide 8 4UNITIKA ( ER ) Group Ceramide Patent CELAMID of new energy product ?FN?E UNITIKA LTDAFJCEL AMID Europe invention patent ?P071 4910B1 1JEP0714910B1 US invention patent 5,846,939 F4FJ 5,846,939 Japan invention 8.268903 8 44N8.268903
Ingredia - Lactium casein hydrolysate peptides # lngredia - Lactium ?7KJt4At patent Lactium is one of the few food ingredients that have passed the health certification of French Security Control and Supervision Bureau L actium is one of the few food ingredients that has passed the health certification of the French Security Control and Supervision Bureau
Lactium EНРM/СIАА (health certification of European Food Safety Authority (EFSA) ) Lactium EHРM/CIAA (EFSAENt 945 RAB) (EFSA European Food Safety Authority Health Certification)
Lactium has passed the health certification of South Korea Lactiumii 7#4 Authority Appproval 1E ERJ Korea’s Health Certification< /p>
Product patent certified by Therapeutic
Goods Administration XFJSEiG EP 0714910B1,Nov.30,1995. /p>
(DGCCRF) (DGCCRF):?TQ? $tJ iEFETTR (DGCCRF) French Security Award