Genomics is more like a blueprint that can tell us what might happen; Protein omics can tell us exactly what happened and what is happening. It is difficult to provide information such as post-translation modification, localization and interaction of proteins by simply decoding the genome, which contains the most direct and important information such as how life activities unfold and why pathological processes occur.
In the state of cancer, the relationship between genome and protein Group is quite similar to an allusion-playing a vassal in a bonfire: at the end of the Western Zhou Dynasty, Zhou Youwang smiled for Princess Bao Bo and lit the beacon tower used in the border for no reason, which made all the vassals travel long distances and compete for rescue, and made the King You broke his promise to the vassal and died in the Western Zhou Dynasty.
Protein is like a "beacon tower" in DNA drawings. DNA can only design the structure of beacon towers and where to build them. However, the deviation between the beacon tower and the drawings caused by reality is not reflected in DNA. More importantly, there is no case of "bonfire against the prince" that far exceeds the general deviation in DNA drawings.