50% decoction has strong antibacterial effect on Shigella dysenteriae and Staphylococcus aureus, and the effective concentrations are 1: 1024 and 1:5 12, respectively. It has strong antibacterial effect on typhoid fever, paratyphoid A, paratyphoid B and dysentery (Freund's, Bowie's and Thorne's). Oral absorption is good (rats), and the discharged urine also has certain antibacterial effect.
2. Anti-spirochete effect
50% decoction has strong inhibitory effect on leptospira icterohemorrhagic in vitro (plastic plate method and test tube method); All kinds of extracts have different degrees of anti-spirochete effect in vitro, among which ether extract has better effect; Blood collection after gastric perfusion in guinea pigs and urine collection after subcutaneous or intravenous injection in rabbits still have certain effects; When treating guinea pigs or golden hamsters, the ether extract of Senecio scandens is not effective, and only Senecio scandens mixture (including Bupleurum, grapefruit and pomegranate peel) has certain protective effect on guinea pigs.
3. Other functions
When the decoction is in the test tube, the concentration of 1:40 can inhibit Trichomonas vaginalis. Alkaloids or effective components isolated from different parts of Senecio scandens produced in Europe have paralyzing effect on motor nerves, causing contraction of isolated guinea pigs and having digitalis-like cardiotonic effect. Seneciosarrace-nius, a plant of the same genus, put forward a bottle of Sarracine, which can excite the central nervous system first and then inhibit it, lower blood pressure, and has obvious spasmolytic effect on the intestine of rats. Some people have suspected that Senecio alkaloids have carcinogenic effects. After experiments on rats and mice, they think that the liver has obvious degeneration, necrosis and inflammatory changes, but it is not a carcinogen. The soaking solution of Senecio scandens treated with ion exchange resin (containing no alkaloid, but reducing sugar, phenol, amine, etc.). ) has the functions of slowing heart rate, prolonging Q-R gap, lowering blood pressure and reducing respiratory rate. Different species of Senecio scandens in other parts of the world (Europe, South America, Africa, Australia), such as human and cattle, can be poisoned after eating, especially causing cirrhosis. The pyrrolizidine alkaloid contained in Senecio scandens has anti-tumor effect, which is related to hepatotoxicity. See big white straw.
4. Toxicity
Acute and chronic poisoning of pyrrolidine alkaloids containing hepatotoxicity can cause hepatic sinus obstruction syndrome, hepatic macrocytosis or hepatic fibrosis. ① For the treatment of various inflammatory diseases, the extract tablets (each tablet weighs 0.35g) are generally decocted in water, taking 3 tablets every 2 days, 4 times a day, and reducing the dosage for children as appropriate. By observing 1338 cases of 29 kinds of inflammatory diseases, 830 cases (62%) were cured, 334 cases (25%) were improved, and 174 cases (13%) were ineffective. Among them, the curative effect on upper respiratory tract infection, acute tonsillitis, lobar pneumonia, acute bacillary dysentery, acute enteritis, acute appendicitis and erysipelas is more prominent. Only a few patients have symptoms such as nausea, loss of appetite and increased stool frequency during taking. In addition, allergic drug eruption 1 case was found, which improved after using antiallergic drugs.
② 50% Senecio Senecio eye drops were used to treat various ophthalmic diseases, with a drop of 1 drop every 2-4 hours, including 200 cases of acute and subacute conjunctivitis, 50 cases of chronic conjunctivitis 150, 60 cases of acute trachoma, 40 cases of chronic trachoma (scar), 20 cases of swimming pool conjunctivitis, 30 cases of superficial punctate keratitis and 60 cases of dendritic keratitis. After treatment, 378 cases were markedly effective (63%), 265,438+05 cases were effective (36.8%), the total effective rate was 98.8%, and 7 cases were ineffective (65,438+0.2%).
In addition, 32 cases of acute conjunctivitis were treated with Jiuliming eye drops, all of which were cured. Compared with chloramphenicol eye drops treatment group (18 cases), conjunctival sac secretion was cultured as Staphylococcus aureus, and the results showed that the negative bacterial culture was very close to the average days of clinical cure.
In addition, 62 patients with central choroiditis of retina were treated by auricular point injection of 200% Senecio Senecio injection. After 1 ~ 2 courses of treatment, 28 cases were basically cured (vision recovered to 1 or above. O), 7 cases were markedly effective, 2/kloc-0 cases were effective (slightly improved vision), 4 cases were ineffective and 2 cases were deteriorated.
Treatment: Ear points are divided into two groups: 1 group is kidney and eye points, and the second group is liver and eye points. Inject 1 time every day, and the two groups of acupoints are injected alternately. 10 day is a course of treatment, and the second course of treatment is conducted every 2 ~ 3 days. 0. 1 ml (elevation) can be injected into liver and kidney points respectively; 0.4 ml can be injected into eye and eye point respectively. Senecio scandens has no contraindications and side effects in the treatment of this disease, and the cure rate is higher within 1 month.
③ Treatment of trichomonal vaginitis After routine vaginal irrigation, cotton gauze with tail was dipped in 100% Senecio scandens solution, and it was taken out by the patient 24 hours later. If there are many trichomonads, you can first wipe the vaginal wall with a cotton swab or cotton ball dipped in medicine, and then put a gauze plug. /kloc-0 once every other day, 5 times as a course of treatment, and the treatment is suspended during menstruation. 120 patients' symptoms disappeared and leucorrhea decreased or disappeared after treatment. After 1 week, 99 patients with negative leucorrhea were classified as cured, accounting for 82.5%. Symptoms are relieved, leucorrhea is reduced, and the number of trichomonas is reduced 16 cases, which is classified as progress, accounting for12.5%; After 5 times of treatment, the symptoms disappeared and leucorrhea decreased, but 6 cases (5%) were positive by leucorrhea microscopy.
④ Treatment of leptospirosis Seven cases of moderate and mild leptospirosis of influenza typhoid type were treated with Qianliguang mixture, all of which were cured. (1) Treatment of rotten eyelid eyes: Cook the bamboo shoots wrapped in Jiuli grass and screw them into the eyes. (Experience Prescription)
② Treatment of eye pain caused by wind and fire: Senecio scandens 100g, decocted in water and smoked. (Jiangxi folk herbs)
③ Treatment of chicken blindness: 50 grams of Senecio scandens, chicken liver 1 piece. Wearing stew clothes. (Jiangxi folk herbs)
④ Treatment of carbuncle and sore poison: 50 grams of Senecio scandens (fresh), decocted in water; In addition, use a proper amount of Senecio scandens (fresh), decoct in water and wash outside; Then mash it with proper amount of Senecio scandens (fresh) for external application. (Jiangxi herbs)
⑤ Treatment of long-term unhealed beriberi and eczema: Senecio scandens, decocted twice in water, filtered, combined decoctions, concentrated into paste with slow fire, diluted into thin paste with a little boiled water or sesame oil, and rubbed on the affected part twice a day; Do not use infant fetal ringworm. (Jiangxi folk herbs)
8 Treatment of wet itching between toes, anal itching and vaginal itching: appropriate amount of Senecio scandens, decocted, and washed the affected area. (Jiangxi folk herbs)
⑦ Treatment of Liriodendron chinense, tinea capitis, dry and wet tinea sores: Senecio scandens and Xanthium sibiricum are equally divided. Concentrate the decoction into paste and apply it to the affected area. (Jiangxi folk herbs)
⑧ Treatment of scrotal pruritus: Mash Senecio scandens, decoct with water to remove residues, then decoct with slow fire to form a thick paste, mix it with Chinese tallow oil and apply it to the affected area. (Common Folk Herbs in Zhejiang)
9. Treatment of scabies and swollen poison: decoct Senecio scandens with water for external application, and take 50 grams of Senecio scandens with water. (Common Folk Herbs in Zhejiang)
Indications for the treatment of influenza; Fresh whole grass of Senecio scandens 50-100g. Decoct with water. (Jiangxi Handbook of Materia Medica)
⑾ Decoction for fire injury: eight parts of Senecio scandens and two parts of Bletilla striata. Decoct with concentrated juice for external use. (Jiangxi herbs)
⑿ Control Department: Senecio scandens 25-40g. Soak in boiling water instead of drinking water. (Fujian Chinese herbal medicine)
[13] Malaria control: Senecio scandens, brown sugar, sweet distiller's grains and * * * soup. (Jiangxi Handbook of Materia Medica)
14. Treatment of various acute inflammatory diseases, bacillary dysentery, toxemia, septicemia, mild intestinal typhoid and Pseudomonas aeruginosa infection: 25g of Senecio scandens, dandelion, Cymbidium hybridum, Centella asiatica, lalang grass rhizome, Phyllanthus urinaria and honeysuckle vine leaves. Decoct in water every six hours. Mu Ba Maw (Jiangxi Handbook of Materia Medica): It can treat upper respiratory tract infection, tonsillitis, pharyngolaryngitis, pneumonia, conjunctivitis, dysentery, enteritis, appendicitis, acute lymphangitis, erysipelas, furuncle, eczema, allergic dermatitis and hemorrhoids. The whole herb is used to treat boils, acute conjunctivitis, eczema, dermatitis, impetigo, rheumatic joint pain, sores, redness, itching, pain and acute conjunctivitis.
Yi Yao daily car repair, several commitments: the whole grass is used for rheumatic pain, sores, redness, itching, acute conjunctivitis. Radically cure conjunctival congestion, traumatic injury, blood stasis and swelling, abdominal pain and diarrhea, infantile fetal poison, syphilis and gonorrhea, hemorrhoid and fistula swelling, eczema and scabies, insect and snake bites. Japanese tonic, Japanese tonic, Ninebu, Labubu: The whole herb is used for severe fire, polydipsia, flaming eyes, eye diseases, sores and ulcers, irregular menstruation, diarrhea, colds, malaria, fire burning, scrofula, rheumatic joint pain, hemorrhoids, sore throat.
Institute of Water Medicine: Treating appendicitis with whole grass.
Li Guang, Feng Teng Grass: Root and whole grass treat rheumatic bone pain, traumatic injury, boils and acute conjunctivitis.
Baiyao Jinnuoguang: The whole herb is used to treat sores, acute conjunctivitis, eczema, dermatitis, impetigo, rheumatalgia, sores, redness, itching and pain. Jinguiguang: whole grass cures sore poison and acute conjunctivitis; External treatment of eczema, dermatitis and impetigo.
Weixiqu is a kind of medicine of Lahu nationality, which has the same function as Yao Lu in Yunnan of Bai nationality.
Jingpo Medicine Ru: Treating pneumonia, enteritis and allergic dermatitis. Knife Han Mao: The function is the same as that of the Jingpo people's Dehong Medical Record.
De 'ang's medicine knife is fine: its function is the same as that of Dehong's medicine record of Jingpo nationality.
She medicine Herb is used to treat upper respiratory tract infection, tonsillitis, pharyngolaryngitis, pneumonia, conjunctivitis, dysentery, enteritis, appendicitis, erysipelas, furuncle, eczema, allergic dermatitis and hemorrhoids.
Plum-yellow taste of Dong medicine: whole grass cures burns and scalds. Nugs wangc meep: the whole grass is mainly used for brewing ghost syndrome (wind mass), and Binmen point (acute eczema) is called Dong medicine. Macelo Wong Flavor: Treating sores, carbuncle and swelling with whole grass [5 1].
Miao medicines Bux gub sheb (defeated by shooting), Vob wik nax (nest and that), Uab miknaix (frog Minei) and Nbaox jat nyox gongb (thin plus a little supply): Miao medicines for treating eye redness, pain and tears with whole grass. Leaves are mainly used to treat eye swelling, burning pain, tears, Leigong syndrome and high fever. Whole grass treats wind-heat cold, red eyes, swelling and pain, diarrhea, eczema and furuncle. Wu Ye Mouth, Five Powder: Whole Herbs Treat Cold, Fever and Body Pain.
A Geng, a Tujia medicine: the whole herb is mainly used to treat sore throat, red eyes, blisters and boils, persistent phlegm and itchy skin.
Hani medicine pollutes OTA: decoct and wash roots and leaves to treat conjunctivitis.
Yao medicine is virtuous and laborious, but it means less light: whole grass cures diarrhea, cold and fever; Decoct and wash with water to treat conjunctivitis, skin infection, ulcer and furuncle.
Zhuang medicine, once a day, dyeing, showing signs, if, next chapter, dental blindness string: stem and leaf for pneumonia, diarrhea, fever in children, laryngitis, mumps, night blindness, osteomyelitis, otitis media, ulcers and fractures for external treatment.
Whole grass (Senecio scandens): bitter and cold. A little poisonous. Clearing away heat and toxic materials, cooling blood to reduce swelling, clearing liver and improving eyesight. Can be used for treating conjunctival congestion, typhoid fever, dysentery, wind-heat cough and asthma, moth, diarrhea, common cold, carbuncle, eczema, allergic dermatitis and hemorrhoid.