Biology (071000) (first-level master's degree program) Physiology (071003) Physiology is a science that studies the life activities and laws of the body. It mainly studies the functions of cells, tissues, organs and cells under normal conditions. Various life activity phenomena of the system, the generation mechanism of physiological functions, activity rules and the interactions and connections between them. Physiology is an extremely important basic theoretical subject in life sciences. The master's degree program in physiology has relatively strong teaching staff and high academic level, and the structure of the academic team and talent echelon is reasonable. There are currently 2 professors, 2 associate professors, and 2 young and middle-aged doctoral lecturers, most of whom have doctoral degrees.
Since obtaining the master's degree in physiology in 2003, it has actively trained many graduate students, two of whom have won the title of Outstanding Graduate Student in South Guangdong. The tutors of the Physiology Master's Program are currently responsible for a number of scientific research projects such as the National Natural Science Foundation, the Guangdong Provincial Natural Science Foundation, and the Ministry of Education's Scientific Research Start-up Fund for Returned Overseas Students. The teachers in this teaching and research section serve as the heads of the body balance, digestion and nutrition, cardiovascular and respiration, functional experiments and medical English modules of our hospital.
One of the research directions: Male reproductive physiology and male reproductive pathophysiology. The current focus is on the study of the pathophysiological mechanisms of diabetes-related male reproductive dysfunction. This direction is dedicated to studying the pathophysiological mechanisms of diabetes-related male reproductive disorders, especially the occurrence and development of diabetic erectile dysfunction. The research team used electrophysiology and pharmacology experimental techniques, such as in vivo recording of intracavernous sinus pressure in rodents, in vitro detection of the relaxation and contraction function of penile corpus cavernosum smooth muscle, and chronic drug intervention technology using micro-osmotic pumps, combined with modern Molecular biology experimental methods are used to deeply explore the new mechanisms of diabetic erectile dysfunction from the overall and cellular levels. This work received multiple grants from the National Natural Science Foundation and the Guangdong Provincial Natural Science Foundation.
Research direction two: Cell physiology Cell physiology refers to the branch of physiology that studies the functional characteristics and regulatory rules of body cells and cell groups at the cellular level. Cells are the basic structural and functional units of the body. The main contents of classic cell physiology include: the basic chemical composition and molecular structure of the cell membrane and the membranous structures that make up other organelles; the transmembrane transport function of different substance molecules or ions; the transmembrane transport function that is the basis for cells to accept external influences or the interaction between cells. Membrane signal transduction function; cell bioelectricity and related phenomena based on the movement of different charged ions across the membrane; and how muscle cells undergo mechanical contraction activities triggered by electrical changes in the cell membrane, etc. The main research methods used in this research direction include: patch clamp recording, ***focus/two-photon laser scanning microscopy imaging, micro-perfusion drug administration and local instantaneous micro-pressure drug administration, etc.; it can realize cell morphology, cell membrane channel current, Dynamic changes in intracellular calcium signals and intercellular interactions can be observed simultaneously and in real time. The results are intuitive, accurate and reliable, and can conduct more detailed research on related physiological functions and their mechanisms (such as transmembrane signal transduction pathways). Experimental models or specimens involved in this research direction include: brain slices (neurons and glial cells), pancreatic tissue and pancreatic cells, cardiomyocytes, etc.; in recent years, it has also been gradually combined with clinically relevant disease models and transgenic animal models. The research projects undertaken include: two National Natural Science Foundation general projects, one National Natural Science Foundation international cooperation and exchange project, one Guangdong Provincial Natural Science Foundation project, one Ministry of Education Scientific Research Start-up Fund project for returned overseas students, and on-campus Two research funds; published several relevant papers included in SCI, and obtained a national invention patent (Patent No.: ZL 2006 1 0132353.2) and a utility model patent (Patent No.: ZL 2011 2 0230370.6); related experiments at home and abroad The laboratory has closer exchanges and scientific research cooperation.