What does that Hong Kong citizen t2 1 do?
Minlan T2 1 was originally developed as a non-invasive prenatal detection method for Down syndrome screening, but the research data in recent years show that this detection is also very good for screening fetal 18- trisomy syndrome and 13- trisomy syndrome. This diagnostic technique was developed by the Department of Chemical Pathology of the Chinese University of Hong Kong. The Chinese University of Hong Kong holds several patents or has applied for patents on this technology. During pregnancy, the fetus releases DNA in the maternal blood circulation. The fetal DNA was analyzed by T2 1 method, and the DNA molecules of chromosome 2 1, 18 and 13 in maternal plasma were detected. If the number of DNA molecules on chromosome 2 1 in blood samples is abnormally increased, it means that the fetus may have Down syndrome. Large-scale clinical trials have confirmed that the detection rate of Down syndrome fetus is as high as 99.5438+0%. The false positive rate of this method is 0.65438 0%. In addition, if the number of DNA molecules on chromosome 18 in blood samples is abnormally increased, it means that the fetus may have 18- trisomy syndrome. The research data showed that the detection rate of fetal T2 1 with 18 trisomy syndrome was over 99.9%, and the false positive rate was 0.4%. If the number of DNA molecules on chromosome 13 in blood samples is abnormally increased, it indicates that the fetus may have 13- trisomy syndrome. The research data showed that the detection rate of T2 1 pair 13- trisomy syndrome was as high as 9 1.7%, and the false positive rate was 0.3%. The phenomenon of false positive rate reflects that not all positive results are based on down syndrome, 18- trisomy syndrome or 13- trisomy syndrome. Therefore, the positive test results must be further diagnosed by amniocentesis or villus sampling. In addition, T2 1 cannot detect all fetuses with Down syndrome, 18- trisomy syndrome or 13- trisomy syndrome. Please note that in some special cases (accounting for 0.9% of all samples), due to many factors (such as the low content of fetal DNA in blood samples), we cannot provide the test results of very few cases. In order to continuously improve the effectiveness of this diagnostic technique, we sincerely seek your cooperation and hope that you can provide us with relevant information about your pregnancy and delivery (such as amniocentesis or chorionic villus sampling results, delivery results, etc.). ) Go through your obstetrician at your convenience.