What is ichthyosis? Ichthyosis is very common, and the symptoms of patients are severe in winter and lighter in summer. Skin diseases mainly caused by keratinocyte differentiation and abnormal epidermal barrier function. Clinical symptoms of ichthyosis are characterized by scaly skin all over the body. Generally speaking, hereditary ichthyosis is the most common, and genetic mutations related to components of the skin barrier can cause the disease.
Ichthyosis is a genetic disease and the most common keratosis disease. One in 250 normal people may suffer from it. Children with congenital ichthyosis often develop dry and flaky skin within a few months of birth. In severe cases, the scales can spread to the trunk, scalp, forehead and cheeks. The severity depends on the season and climate, is aggravated in dry and cold environments, and cannot be cured.
What is ichthyosis? The most common one is autosomal dominant ichthyosis vulgaris. It often starts to appear a few months after birth. The condition worsens with age. Symptoms are heavier in winter and lighter in summer, and the skin is dry. , the scales are yellow-brown, diamond-shaped or polygonal, with raised edges and a chaff-like center close to the skin. The rash mainly occurs on the side of the outstretched limbs, followed by the back. There may be mild scales on the head. In severe cases, it can spread to the whole body. It generally does not involve the armpits, buttocks and skin folds. Most patients feel discomfort due to reduced secretion of sebaceous glands and sweat glands in the skin all over the body, resulting in dry skin and less sweating.
The other type is sex-linked hereditary ichthyosis vulgaris, which is inherited recessively and only occurs in males (females are carriers). It develops soon after birth. The rash is widely distributed and can also affect the flexural sides and folds. The abdomen is heavier than the back. The rash scales are larger and more obvious. It can affect the elbow fossa, armpits, armpits, and the eyes can also be affected.
The symptoms of ichthyosis are not obvious in humid and warm environments. When the weather turns cold, cold, or dry, people's sebum and sweat secretion decreases, and the fish scale-like changes in the skin will be very obvious. The so-called dead skin that appears at this time is actually caused by abnormal keratin metabolism in the stratum corneum of the skin, or abnormal cell lipid metabolism. Unfortunately, there is currently no cure for this disease at home and abroad. Treatment mainly focuses on relieving symptoms, increasing the moisture content of the stratum corneum, and promoting normal keratinization of the skin.
What is ichthyosis? Congenital severe ichthyosis is a serious hereditary skin disease that requires the application of drugs and oral drugs to relieve discomfort. But Hanghang is only 8 years old and is not suitable for oral medication, otherwise it will affect his growth. Most people take long-term medication, either applied or taken orally, to relieve their symptoms.