Which medicines are compound western medicines?

Recently, I accepted the compound preparation because cocktail therapy for AIDS is very effective, and cocktail is the compound preparation. In addition, modern empirical medicine has a better understanding of diseases. It is known that diseases are not caused by a single cause, but may be caused by problems in the physiological system or diseases caused by many factors. For example, from gene mutation to the proliferation of cancer cells invading tissues and vascular mechanisms, the proliferation of cancer is complex. Therefore, in the process of different cancer cells, drugs with different mechanisms will increase the therapeutic effect. For example, COX2 inhibitors can not only relieve pain and treat osteoarthritis and rheumatoid arthritis, but also treat early stage. There is another reason. The appearance of compound preparation is also an extended protection means for patented drugs after they expire, which can continue to protect the existing market of patented drugs. Briefly describe the following well-known compound preparations:

OgmentIn Europe, GlaxoSmithKline's best-selling antibiotic is Ogmentin. This preparation was developed in 198 1 and approved by FDA on August 6, 1984. This β -lactam compound preparation has been on the market for 20 years, but it lasted for a long time. The main reason is that if only semi-synthetic penicillin amoxicillin is used, it is easy to produce drug resistance. If β -lactamase inhibitors, such as clavulanic acid, are added, the effect is very good. According to the report of Med Ad News in 2003, although its patent has passed, its market value is still $65.438+35 billion, ranking 43rd.

Co-DiovanDiovan is the first ARB antihypertensive drug in the world, and its clinical safety and effectiveness have been confirmed by large-scale clinical trials with as many as 50 thousand people around the world. Compound Diovan is a compound dosage form of Diovan plus diuretic, and a single buccal tablet has dual effects, which can help hypertensive patients actively control their blood pressure and achieve the ideal blood pressure control goal. According to the statistics of Medad News in 2003, the market value of Co-Diovan and Diovan was $2.425 billion.

Rifotard, a drug for treating pulmonary tuberculosis, contains rifampicin 120mg, isoniazid 80mg and pyrazinamide 250mg each, and it has three different therapeutic components in order to increase the therapeutic effect.

The appearance of Symbyax compound preparation is also an extended protection means after the patent medicine expires. For example, Lilly's Symbyax is a psychotropic drug that can cure bipolar disorder. In fact, it is a compound preparation of olanzapine and fluoxetine, which can continue to protect the market of Zyprexa and fluoxetine.

Kangbiwei in the treatment of AIDS

TrizivirTrizivir treats AIDS.

It will be a trend to develop the compound preparation of Lipitor plus tostrepib. At present, Pfizer has developed a compound preparation of Lipitor and Torcetrapib to synthesize a cholesterol inhibitor. At present, this compound preparation,