Syndrome Differentiation and Classification of Liver Cancer Treated by Beijing Hospital of Traditional Chinese Medicine

Liver cancer has complex symptoms, many complications and different manifestations at different stages of the course of the disease, so the syndrome differentiation and classification are not exactly the same. Now only the common syndromes are summarized as follows:

1. Liver-qi stagnation type

Main symptoms: hypochondriac pain, right hypochondriac swelling pain, chest tightness, aggravation after anger, improper diet, large liver, thin and white tongue coating and thready pulse.

Syndrome differentiation: liver depression and qi stagnation.

Treatment principle: soothing the liver and regulating qi.

Prescription: Cidan capsules, 5 capsules each time, 4 times a day. Relieve symptoms (Zhengtongkang), 65438±0g each time, three times a day. Fuzheng Guben Capsule, 5 capsules each time, 4 times a day.

Decoction: Bupleurum chinense 12g, Angelica sinensis 12g, Hangshao 15g, Atractylodes macrocephala 10g, Poria cocos 10g, Radix Curcumae 10g, Rhizoma Cyperi 10g.

Note: the liver governs the discharge, but the liver qi does not discharge, which is blocked by collaterals, so it is manifested as hypochondriac swelling and pain; Dyspnea, qi stagnation and chest tightness; Liver depression trapped the spleen and the spleen lost its function, so it was ignored; Qi stagnation leads to blood stasis, so hypochondriac mass can be seen. Soothing liver and regulating qi. Bupleuri Radix, Radix Curcumae, Rhizoma Cyperi, and Pericarpium Citri Reticulatae Viride soothe the liver, regulate qi, relieve depression and relieve pain; Danggui, Hangshao and Shayuanzi soften liver and nourish blood; Zhali Qi and Huoxue in August; Atractylodis Rhizoma, Poria and Glycyrrhrizae Radix.

2. Qi stagnation and blood stasis type

Main symptoms: hypochondriac pain, tingling, backache, immobility, especially at night, hypochondriac swelling, dark tongue, ecchymosis, thin or astringent pulse.

Syndrome differentiation: qi stagnation and blood stasis, aversion to blood.

Treatment principle: promoting qi and blood circulation, removing blood stasis and resolving food stagnation.

Prescription: Compound zedoary Xiaoliu capsule, 5 capsules each time, 4 times a day. Relieve symptoms (Zhengtongkang), 65438±0g each time, three times a day. Fuzheng Guben Capsule, 5 capsules each time, 4 times a day.

Decoction: Lignum Dalbergiae Odoriferae10g, Rhizoma Corydalis10g, Rhizoma Sparganii10g, Rhizoma Curcumae10g, Eupolyphaga Seu Steleophaga10g, 30g of raw oyster, 20g of Zhaba in August, and 0g of Radix Paeoniae Rubra/kloc-0.

Note: qi stagnation for a long time leads to blood stasis, stagnation in the liver collaterals, and stagnation leads to pain, so the lump is getting bigger, the hypochondriac pain is like a thorn, and the pain is not moving; Liver blood is yin, night is yin, and blood stasis at night is painful. Treatment is promoting qi and blood circulation, removing blood stasis and promoting digestion. Rhizoma Sparganii, Rhizoma Curcumae, Radix Paeoniae Rubra and Eupolyphaga Seu Steleophaga promote blood circulation and remove blood stasis; Lignum Dalbergiae Odoriferae, Rhizoma Corydalis, Radix Curcumae, Rhizoma Corydalis and Herba Chelidonii are used for regulating blood circulation, promoting qi circulation and relieving pain; Angelica sinensis and Radix Paeoniae Alba nourish blood and soften liver; Pangolin and oyster nourish yin, soften hard mass and disperse hard mass.

3. Damp-heat toxin type

Main symptoms: aggravation of illness, fever, sweating, irritability, dry mouth and bitter taste, yellow eyes, stabbing pain in the ribs, abdominal distension, nausea and anorexia, dry urine, red and dark tongue, yellow and greasy tongue coating, and slippery or slippery pulse.

Syndrome differentiation: damp-heat in liver and gallbladder, blood stasis and toxic blood stasis.

Treatment: clearing away heat and gallbladder, purging fire and detoxifying.

Prescription: Cidan capsules, 5 capsules each time, 4 times a day. Relieve symptoms (Zhengtongkang), 65438±0g each time, three times a day.

Decoction: Desmodium styracifolium 30g, Polygonum cuspidatum 30g, Curcuma longa15g, Gardenia10g, Cortex Moutan15g, Herba Artemisiae Scopariae 20g, Herba Taraxaci 30g, Herba Lycopodii 30g, Solanum nigrum 30g, Herba Duchesneae 30g, and Cortex Magnolia Officinalis 30g.

Note: Liver-qi stagnates for a long time, and when qi is abundant, fire is abundant, so qi stagnation will turn into heat, which will accumulate in the liver and gallbladder, causing irritability, dry mouth and bitter taste; Damp-heat blocks the biliary tract, turning the body and eyes yellow. Both the tongue and pulse show symptoms of bleeding, blood stasis, toxin and fiery heat. Herba Lysimachiae Christinae and Herba Artemisiae Scopariae can clear away damp-heat, while Curcuma longa can soothe liver and gallbladder, promote blood circulation and remove blood stasis; Polygonum cuspidatum, Fructus Gardeniae, Cortex Moutan, Taraxacum mongolicum, Solanum lyratum Thunb, Solanum nigrum, snake and sheep's hoof are used for cooling blood and detoxicating, clearing heat and purging fire; Cortex Magnolia Officinalis, Cortex Periplocae and Semen Raphani promote qi circulation, promote stagnation and relieve bloating.

4. Liver yin deficiency type

Main symptoms: hypochondriac pain, persistent pain, no appetite, low fever, night sweats, fever, dizziness, jaundice, hematuria, abdominal distension, blue veins exposed, hematemesis, hematochezia, subcutaneous hemorrhage, red tongue with little coating, and thin and thready pulse.

Syndrome differentiation: deficiency of liver and blood, yin deficiency and internal heat.

Treatment: nourishing blood and softening the liver, nourishing yin and nourishing blood, cooling blood and stopping bleeding.

Prescription: Cidan capsules, 5 capsules each time, 4 times a day. Relieve symptoms (Zhengtongkang), 65438±0g each time, three times a day. Fuzheng Guben Capsule, 5 capsules each time, 4 times a day.

Decoction: 20g of Radix Rehmanniae, 0g of Radix Paeoniae Alba15g, 0g of Radix Angelicae Sinensis10g, 0g of Fructus Ligustri Lucidi15g, 20g of Eclipta prostrata, 20g of raw tortoise plastron, 20g of raw turtle shell, 0g of cortex moutan15g, and tender Artemisia annua15g.

Note: the pathogen of heat toxin belongs to yang, which is easy to be consumed by liver and gallbladder, and the liver and blood are deficient for a long time, so hypochondriac pain is dull; Yin deficiency leads to internal heat, and pathogenic toxin accumulates in it, so symptoms such as vexed heat, low fever, jaundice, bleeding, etc. Liver-qi is contrary to spleen deficiency, water is not wet, and abdominal distension, such as drum and limb swelling, occurs when water is stopped in the abdomen. Treatment is nourishing yin and softening the liver, benefiting qi and nourishing blood. Radix Rehmanniae, Fructus Ligustri Lucidi, Ecliptae Herba, Ziziphi Spinosae, Carapax Trionycis, and Corni Fructus for nourishing yin and clearing heat; Radix Paeoniae Alba and Radix Angelicae Sinensis nourish blood and soften liver; Peony and Artemisia annua clear heat; Raw Astragalus membranaceus, Poria cocos peel and raw yam are used for invigorating spleen and benefiting qi; Shashen Yiqi Yangyin; Lobelia chinensis clearing away heat and promoting diuresis.

Clinical medication: low-heat plus Artemisia annua, Cortex Lycii, Cynanchum atratum, Radix Bupleuri, Red Fruit, Cortex Moutan, Radix Rehmanniae, Carapax Trionycis, etc. Gypsum, Gypsum Fibrosum, Talcum for high fever, or water, cornu Bubali and antelope horn powder; Or add Qingkailing, Niuhuang Qingre Powder, etc. For jaundice, Herba Artemisiae Scopariae, Rhizoma Curcumae Longae, Rhizoma Polygoni Cuspidati, Herba Lysimachiae Christinae, and Herba Hedyotidis Diffusae are added. For bleeding, cacumen Platycladi, Herba et Gemma Agrimoniae, Herba Hedyotidis Diffusae, nidus Vespae, Radix Rehmanniae, Cortex Moutan, Cornu Bubali, Radix Notoginseng (processed) and Yunnan Baiyao (processed) can be added. Lignum Dalbergiae Odoriferae, Rhizoma Corydalis, Radix Curcumae, Chelidonium majus, Yunnan Baiyao, Myrrha, Olibanum, Fructus Toosendan, Lignum sappan, Xu Changqing, Radix Zanthoxyli, etc. Radix Aucklandiae, Cortex Magnolia Officinalis, Pericarpium Citri Tangerinae, Pericarpium Arecae, Semen Raphani, Arecae Semen and Fructus Aurantii Immaturus can be added for abdominal distension. Alisma orientalis, Euphorbia helioscopia, Polyporus, Poria, Plantago asiatica, Phytolacca acinosa, Lobelia chinensis, Dichou, etc. Pinellia ternata, bamboo shavings, fulonggan, Inula, ochre, Yushu Dan, etc. It can be used for treating nausea and vomiting. Radix Aconiti Lateralis Preparata and Cortex Cinnamomi are added for patients with cold limbs. Loose stool is added with ginger, tsaoko, catechu, atractylodes rhizome, fried lentils, etc.

Attachment: Professor Zheng, Vice Chairman of Cancer Branch of Chinese Medicine Association, TCM Syndrome Differentiation and Treatment of Liver Cancer —— Three Differentiation, Three Avoidances and Three Essentials (journal of traditional chinese medicine)

Three differences

The causes of cancer are qi stagnation and blood stasis, phlegm and blood stasis, and mutual struggle. Therefore, in treatment, early attack is supplemented; In the medium term, it is appropriate to attack and make up; In the later stage, it is advisable to make up for the middle attack, but it cannot be forced by stages. In short, only by flexible application due to illness can we defeat the enemy. The drugs used, whether tonic or powder, should try to choose products with anticancer effect, which can get twice the result with half the effort.

First, distinguish deficiency, strengthen body resistance and fight cancer

"Nurturing its constant accumulation and eliminating its self" shows the great significance of strengthening the body resistance in tumor treatment. To strengthen the body, we must first identify the loss of qi and blood, yin and yang, so as to "benefit the loss and replenish the deficiency", reconcile yin and yang, biochemical qi and blood, promote human immune function and enhance its anti-cancer effect. Whenever liver cancer is found, it is mostly in the middle and late stage, so it is more appropriate to replenish it and strengthen the body resistance and eliminate evil.

Qi deficiency syndrome is characterized by listlessness, low voice, dizziness and spontaneous sweating, pale complexion, pale tongue with thin coating and weak pulse. Suitable candidates: Ginseng, Codonopsis pilosula, Radix Pseudostellariae, Radix Astragali, Atractylodis Rhizoma, Rhizoma Dioscoreae, Radix Glycyrrhizae, etc. Astragalus membranaceus should be eaten raw, the dosage is 30 ~ 60g;; Codonopsis pilosula or Pseudostellaria heterophylla, 20 ~ 30g, radish seeds are added to prevent stagnation. In the Qing Dynasty, radish seeds were used together in Fu Qingzhu, and radish seeds also had anti-cancer effects.

Blood deficiency syndrome is characterized by dizziness, fatigue, palpitation, insomnia, dark fingernails, pale tongue and thready pulse. Commonly used: Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Paeoniae Alba, Radix Rehmanniae, Radix Salviae Miltiorrhizae, etc.

Yin deficiency syndrome is characterized by fever in the afternoon, fatigue and insomnia, night sweats and nocturnal emission, dizziness, dry mouth and throat, red tongue with little or no coating, and rapid pulse. Optional: Radix Asparagi, Radix Ophiopogonis, Radix Adenophorae, Rhizoma Polygonati Odorati, Fructus Ligustri Lucidi, Ecliptae Herba, Carapax et Plastrum Testudinis, etc.

Yang deficiency syndrome is characterized by cold form and cold limbs, pale complexion, loose stool or indigestion, pale and fat tongue, white and slippery fur and slow pulse. When selected: cinnamon, epimedium, psoralea corylifolia, antlers, acanthopanax bark, leek seeds, etc. Others such as lily, lentil, mistletoe, dipsacus root, Eucommia bark, soybean, walnut branch (clip), Ficus pumila, hemp seed, pea, etc. Both of them have the function of strengthening the body resistance and resisting cancer, and can be used according to the syndrome.

Second, dialectical elimination of evil and cancer control.

In the treatment of liver cancer, the purpose of eliminating pathogenic factors is to eliminate accumulation, including: promoting the circulation of qi to dissipate stagnation, promoting blood circulation to reduce swelling, resolving phlegm and softening hard mass, clearing heat and detoxifying, etc. There are some sayings in Neijing, such as "those who are determined to cut", "those who get in the way", "those who get in the way" and "those who leave behind to attack", so that if evil goes, it will be safe.

Qi stagnation is manifested as abdominal distension or paroxysmal pain, belching and suffocating, thin white or slightly greasy tongue coating, and thready pulse. Suitable choices: Radix Aucklandiae, Radix Linderae, Rhizoma Cyperi, Fructus Foeniculi, Fructus Aurantii, Caulis Bambusae, Radix Curcumae, Rhizoma Curcumae, etc.

Blood stasis syndrome has fixed pain, which is more painful when pressing, or the pain is like acupuncture, which gets worse every night, and the tongue is purple and dark, or there are ecchymosis and unsmooth pulse. Should be selected from: frankincense, myrrh, peach kernel, safflower, corydalis tuber, rhubarb, Sichuan Tianqi, Dendrobium, beehive, chantui, gecko, peony bark, oak, Polygonum cuspidatum, sunflower seed, Euonymus japonicus, turmeric, etc.

Damp phlegm syndrome is characterized by chest tightness and fullness, nausea and vomiting, loose stool, or distended limbs, greasy or yellow fur, full or slow pulse. Can be selected from Cortex Magnolia Officinalis, Fructus Aurantii, Polyporus, Poria, Rhizoma Smilacis Glabrae, Herba Plantaginis, Coicis Semen, Rhizoma Pinelliae, Rhizoma Acori Graminei, Rhizoma Arisaematis, Fructus Trichosanthis, Bulbus Allii Macrostemonae, Herba Dianthi, Folium Pyrrosiae, Plum, Water chestnut, Sargassum, Concha Ostreae, Radix dichroae, Radix Stephaniae, and Folium Pyrrosiae.

There are also products for clearing away heat and toxic materials, which are also important anti-cancer components, such as Hedyotis diffusa, Scutellaria barbata, Taraxacum, Solanum lyratum Thunb, Houttuynia cordata, Lithospermum, Calculus Bovis, Indigo Naturalis, Patrinia, Lobelia Chinensis, Wild Grape Root, Euphorbia humifusa, etc. , you can choose appropriately. Because tumors are caused by pathogens, every pathogen can easily turn into fire, just as the saying goes, "Where there is a lump, there must be yang fire, which smolders in the middle ... It is not easy to clear it with bitter, bitter and cold medicine."

Third, identify diseases and choose drugs to treat cancer.

Due to the different location and nature of the tumor, according to the special situation of liver cancer, appropriate drugs are selected, such as zedoary, salvia miltiorrhiza, giant knotweed, turtle shell, tortoise plastron, American ginseng, Pteris multifida, Prunella vulgaris, Gentiana scabra, Radix Curcumae, ginger, Dictyophora indusiata leaves, bear bile powder, bezoar, etc. , including raw turtle shell, antler and atractylodes rhizome.

Tumor syndrome is actually a refractory disease. In addition to various treatment methods of traditional Chinese and western medicine, adjuvant therapy is also used.

Three taboos

First, avoid breaking blood: in the method of eliminating evil, it is advisable to promote blood circulation, not to break blood. Through clinical observation, the blood-breaking drugs such as Sparganium, Leech, Pangolin and Gleditsia sinensis were used. It has the effect of hardening and relieving pain, but if it is used for a long time, it will easily lead to tumor diffusion or metastasis. Because of the blood-breaking drugs, blood stasis and toxins can swim in the veins. Judging from the clinical survival cases of this disease, most of them have not been prescribed or used for a long time; On the contrary, if it is used continuously, it can take effect for a while, but the prognosis is poor.

Second, avoid alcohol and tobacco: the harm of tobacco, predecessors have long had the commandment of "consuming blood and hurting gas." It is found that if people smoke a lot, they will not only lose their lives, but also the tar produced by cigarettes (an obvious carcinogenic factor) is not only directly related to lung cancer, but also leads to cancers such as laryngeal cancer, esophageal cancer, bladder cancer and pancreatic cancer. Cancer patients will die quickly if they smoke, just like carrying firewood to put out a fire.

The harm of wine is slightly worse than that of cigarettes, because wine is hot and toxic, and spirits are even worse. Bian Que said: "Too much wine will spoil the stomach, break the marrow and steam tendons, and kill people." . Dongyuan said, "Wine fever is poisonous. If you drink it into your stomach, you must first go through the liver and gallbladder. " Patients with liver cancer drink it, stirring the internal wind to ignite the fire, and the wind causes the fire to be heated by the wind, so the dangers of coma, convulsions and blood loss are repeated, and the disaster is not immediate.

Third, taboo medicine: In ancient times, there was an idiom "taboo disease and avoid medical treatment". There are still many people who avoid medical treatment in modern times. In rural areas, there is still a custom of "believing in witches but not doctors". Some people believe in Chinese medicine but not western medicine, or believe in western medicine but not Chinese medicine, thus delaying the superiority of Chinese and western medicine treatment, which is very regrettable.

Three elements

1. Dietotherapy: The ancients said that "garden vegetables are better than delicacies", which is more suitable for cancer patients. You should eat more fresh vegetables, fruits, radishes, coix seed, lentils, lilies, kelp, laver, Hericium erinaceus, tremella, mushrooms and Tricholoma matsutake. And you can also eat clams (mollusks), fish, turtles, turtles and mushrooms.

Second, take good care of them: cancer patients often have anxiety and fear, which leads to the deterioration of their condition. Ling Shu believes that doctors "tell them that they have been defeated, speak in good faith, guide them with convenience, and enlighten them with suffering", so that patients feel broad-minded, optimistic, and establish confidence in overcoming diseases, and ask their families to take care of them and comfort them.

Third, practice: Neijing pointed out that "all diseases are born of qi". Qi is the handsome of blood, and blood is the mother of qi. Practicing qigong can harmonize qi and blood, balance yin and yang, promote metabolism and achieve the purpose of self-regulation.

Medical record card

Example 1 Lin, male 42, cadre. 199565438+1October 12 for the first visit. At the beginning of September this year, the patient was diagnosed with primary liver cancer due to tightness in the right upper abdomen, emaciation and fatigue, and underwent liver cancer surgery in Minhou County Hospital on September 24. But at present, the symptoms have not been alleviated, but have worsened. I came to see a doctor today. Symptoms: pain in the right upper abdomen, tingling, fatigue, anorexia, white and greasy tongue coating, slippery pulse, blood stasis and toxic syndrome, liver depression and qi stagnation, and damp accumulation in the middle energizer. Treatment: detoxification and blood stasis, soothing the liver and regulating qi, eliminating dampness and strengthening the spleen. Prescription: ① Zheng Xiao Pill (Zheng Tongkang), 65438±0g each time, 4 times a day, taken orally after meals. Cidan capsules, 5 capsules each time, 4 times a day. ② Radix Bupleuri 10g, Fructus Aurantii 10g, Radix Paeoniae Alba 30g, Radix Glycyrrhizae 6g, Radix Salviae Miltiorrhizae 10g, Radix Curcumae 6g, Fructus Crataegi 30g, Pericarpium Citri Tangerinae 6g, Rhizoma Pinelliae 10g, Cortex Magnolia Officinalis 6g, Rhizoma Atractylodis 10g, Radix Astragali 30g and Rhizoma Dioscoreae 30g.

Secondary diagnosis (1995165438+10 month 12): After taking the medicine, all the symptoms were relieved and the pain in the liver area disappeared, but the tongue coating was still greasy and the pulse was weak, and the effect was not good. The prescription is the same as before, and the finished medicine and decoction are taken 1 month.

The third diagnosis (199565438+February 15): after a course of treatment, there was no obvious discomfort, weight gain, fragrant smell, good sleep, thin yellow tongue coating and thready pulse. After a long illness, the tumor is sad and has deep blood stasis, and it is still treated in the front. After the third year, it will be treated once a year.

After four consultations (1996 65438+ 10/6), the patient was in a good mental state and full of confidence, just like catching a cold about cancer. Today, I look bright and energetic, my skin is rosy, my tongue is smooth, my tongue coating is thin and white, and my pulse is weak. Prescription: Chinese patent medicine is the same as before, continue to take 1 month. Traditional Chinese medicine decoction is mainly composed of Sini powder, Yueju powder and Jinling powder, and salvia miltiorrhiza, turmeric and hawthorn are added for 30 days.

The fifth diagnosis (1April 7, 996): After taking the medicine, the patient was full of energy and normal. 14 On March 4th, Minhou County Hospital was examined by B-ultrasound, and the liver, gallbladder, pancreas and kidney were normal, and the liver function was basically normal, AFP.

Case 2: Zhang, male, 47 years old. 1996 65438+1initial diagnosis on October 3rd. On February 23rd, 1995, 1532, the patient was diagnosed as primary liver cancer stage Ⅲ, liver cirrhosis and splenomegaly, with low-density shadow in the right posterior lobe of the liver, the maximum being about 8cm×7cm, and retroperitoneal lymphadenopathy. Now I'm looking for a doctor. Symptoms: yellow sclera, yellow and orange body, low back pain caused by pain in liver area, acupuncture pain, short and red urine, slightly knotted stool, yellow and greasy tongue coating and slippery pulse. Syndrome: stagnation of blood stasis and toxin, accumulation of damp-heat and stagnation of liver-qi. Treatment: removing blood stasis and detoxicating, clearing away heat and promoting diuresis, soothing the liver and regulating qi. Prescription: (Zheng Tongkang), each time 1g, 4 times a day; Cidan capsules, 5 capsules each time, 4 times a day. Take it for 30 days ② 30g of Herba Artemisiae Scopariae, 30g of Caulis Saussureae Involucrata, 30g of Herba Hedyotidis Diffusae, Radix Salviae Miltiorrhizae 10g, Radix Curcumae 10g, Fructus Crataegi, Rhizoma Alismatis 10g, Poria 30g, Semen Plantaginis 15g, and Fructus Citri Sarcodactylis 15g.

Second diagnosis (1996.03. 18): After taking the medicine, the condition was stable, yellow eyes, yellow body and yellow urine disappeared, only the liver area was still painful, and the tongue and pulse were as before. Zheng's Shuangbai Decoction was used for treatment for 30 days, while Chinese patent medicine remained unchanged for 30 days.

The third diagnosis (65438+1April 2, 19961): all medicines are exhausted, and if all symptoms are absent, there is no obvious discomfort, with red tongue, thin and white fur and thready pulse. The treatment is the same as the last one.

Press: After taking the medicine, the patient's confidence doubled and he insisted on going to work. He often went to the ballroom to dance and entertain, and he was still alive.

Example 3 Kong Mou, male, 87 years old, retired cadre. 1994 65438+February 14 outpatient department of Shanghai Jing' an Central Hospital (168- 1289), diagnosed as primary liver cancer (massive type). B-ultrasound showed that the right lobe of the liver occupied a space and cholesterol crystallized in the gallbladder. Chest X-ray shows that there are multiple veins in both lungs, the shadow of the hilum of both lungs is thick, the heart shadow extends to the lower left, and the cardiothoracic ratio is 1:2. Electrocardiogram showed frequent atrioventricular premature beats. Ultrasonic description showed a solid hyperechoic mass on the right back of the liver, with the size of about 99 mm× 99 mm× 65, 438+065, 438+06 mm, irregular boundary, internal echo disorder and unclear vascular direction. Agence France-Presse: 240< μ g/L. Take Cidan capsules in Shanghai Jing 'an Central Hospital, four times a day, five capsules each time. After four courses of treatment, the liver was reexamined in the B-ultrasound room of Jing 'an Central Hospital, Shanghai on May 22nd (1803), 1996. The liver is almost normal, and 4 1mm×47mm moderate echo light mass is seen in the right lobe of the liver. AFP20 & lt μ g/L.

Press: The patient has survived for more than 3 years, the liver tumor has shrunk by about 50%, and he has fully recovered without any discomfort. At present, you can go to the park by bike.

Example 4 Lin, male, aged 69. /kloc-0 In May, 994, a mass was found in the right upper abdomen, accompanied by abdominal distension, discomfort and fatigue. In June of the same year 13 in the first affiliated hospital of Fujian Medical University, CT( 103533) showed that the right lobe of the liver was a space-occupying lesion (massive type), the mass size was 97 mm×1000 mm, the AFP quantification was 1085.52 μ g/L, and there were some lesions. August 1994 was transferred to our hospital for treatment. Symptoms during treatment: the right upper abdomen can touch a huge mass, which is hard and can be pushed. The pain in the liver area is severe and stinging. Abdominal distension, umbilical protrusion, abdominal circumference of 97cm, emaciated appearance, B-ultrasound showing ascites volume of about 5000-6000ml, anorexia, blue complexion, dark eyes, yellow and white sclera, orange skin, nausea and vomiting, dysphagia, upset and fever, inability to eat after severe pain, short and red urine and purple tongue. TCM syndrome differentiation: qi stagnation and blood stasis, dampness and blood stasis. Treatment: soothing the liver and regulating qi, clearing away heat and promoting diuresis, removing blood stasis and promoting diuresis, detoxifying and resolving stagnation, invigorating spleen and nourishing stomach. Prescription: ① Cidan capsules, 5 capsules each time, 4 times a day; Symptoms can be relieved (Zhengtongkang), each time 1g, four times a day, continuously taking 1 month. ② Herba Artemisiae Scopariae 30g, Caulis Saussureae Involucrata 30g, Herba Hedyotidis Diffusae 30g, Carapax Trionycis 30g (decocted first), Poria 30g, Rhizoma Atractylodis Macrocephalae 30g, Rhizoma Corydalis 10g, and Melia azedarach 10g, once a day/dose, twice for 30 days. On September 24th of the same year, after taking the medicine, severe pain in the liver area, abdominal distension and ascites persisted, nausea, vomiting and dysphagia persisted, the sclera yellow stain had been removed, the skin yellow stain had subsided, the stool was 5-6 times a day, and the tongue pulse was the same as before. If the disease is the same as before, it must be eradicated slowly and treated properly. It is still slightly adjusted than the previous prescription. Take another 1 month. After taking all the medicines, the symptoms were greatly relieved, ascites disappeared, abdominal circumference was 78cm, and food intake was greatly increased. The patient expressed firm confidence and cooperated with the treatment plan, and his family members took care of him in every possible way. Then according to syndrome differentiation, * * * was hospitalized for 308 days, and all the symptoms were cured. After B-ultrasound and CT examination, the mass was reduced to 12 mm× 10mm, which was more than 8/ 10 compared with the original film. Blood picture, liver function and renal function are normal, AFP.

Example 5 Lin, male, 34 years old. 1June, 1993, due to persistent pain in the right upper abdomen, isotope scanning, ultrasound and CT were performed in Xiamen Hospital of Traditional Chinese Medicine, and it was confirmed that there was a huge space occupying lesion in the liver area. 1February, 993, many cancers were found in the liver area, the largest being 60 mm×70mm, and the postoperative pathology was hepatocellular carcinoma. After the operation, I decided to have radiotherapy and chemotherapy. Because of poor health and obvious emaciation, the patient could not tolerate radiotherapy and chemotherapy, and was transferred to the hospital for treatment on March 6th. 1993. During the treatment, there were swelling and pain in the liver area, loss of appetite, asthma and spontaneous sweating, fear of wind and cold, heart rate 180 beats/min, frequent dizziness, dry mouth and lips, tight and uncomfortable surgical incision, sometimes pain, but no infection, purple tongue and slippery pulse. Syndrome: stagnation of blood stasis and toxin, stagnation of liver-qi and deficiency of both qi and blood. Treatment: removing blood stasis and detoxicating, soothing the liver and regulating qi, benefiting qi and nourishing blood. Prescription: ① Cidan Capsule 10 box, 4 times a day, 5 capsules each time, taken with boiling water; 10 box of compound zedoary Xiaoliu capsules, 4 times a day, 5 capsules each time; Zheng Xiaoli (Zheng Tongkang) 40 bottles, 4 times a day, each time 65438±0g. ② salvia miltiorrhiza 1 0g, curcuma aromatica10g, hawthorn 30g, astragalus membranaceus10g, liquorice 6g, gardenia10g, turtle shell vinegar 30g (fried first), toosendan fruit10g and Polygonum multiflorum 20g. 1 month later, the pain in the liver area disappeared, the physique gradually recovered, the purple tongue turned pale, and other symptoms were relieved. Continue the second course of treatment according to the original prescription.

The second diagnosis (July of the same year 17): after taking the medicine, asthma, spontaneous sweating, fear of wind and cold have recovered, appetite has increased, and there is no discomfort, and the tongue is pale red and white with fur and pulse. This is the trend that blood stasis and toxins are gradually exhausted and healthy qi is gradually restored. However, considering that liver cancer is the king of cancer and is deeply rooted, we must pursue it and not underestimate the enemy. Therefore, in the first prescription, compound zedoary Xiaoliu capsule is added, 5 capsules are taken three times a day, and honey water is used before meals, and five courses of treatment are taken continuously. 1996 12.27 during the free clinic in Xiamen, I followed up with section chief Lin and saw that he was red all over without any discomfort. He still insists on going to work every day and can take part in winter swimming sports activities.

Example 6 Weng, male, 50 years old. 1997 1 26th. The patient has no obvious inducement. 1 24 physical examination, diagnosed as liver cancer. The mass size was12.7 cm×11.2 cm×12.5 cm. In the late stage, there are multiple gallstones in both kidneys, and the signal is abnormal. ② Cann't intubate chemotherapy; ③ Radiotherapy is not suitable; ④ There is no Chinese medicine for treating cancer in our hospital; ⑤ Immunization had no obvious effect, so it was transferred to our hospital for treatment. Symptoms: aggravation of illness, fever, sweating, irritability, dry mouth, bitter taste, yellow eyes, stabbing pain in ribs, full abdominal distension, loss of appetite, short and red urine, dark red tongue, yellow greasy tongue coating and slippery pulse. This is the poison of damp-heat, and it should be treated to clear away heat and promote diuresis, detoxify and dissipate stagnation. Prescription: ① Cidan Capsule and Compound Rhizoma Curcumae Xiaoliu Capsule, 4 times a day, 5 capsules each time; Zheng Xiaoli (Zheng Tongkang) 40 bottles, 4 times a day, each time 65438±0g. ② 30g of Herba Artemisiae Scopariae, 30g of Solanum lyratum Thunb., 30g of Hedyotis Diffusae, 30g of Folium Isatidis, 30g of Rhizoma Smilacis Glabrae 15g, 30g of Alismatis Rhizoma, 30g of Salvia Miltiorrhiza 10g, 30g of Radix Curcumae 10g, and 30g of Fructus Crataegi were decocted with water.

The second diagnosis (February 24th of the same year): After taking the medicine, all the symptoms were relieved, the condition was stable, the lump was enlarged, the yellow body and eyes had subsided, the pain in the liver area disappeared, and occasionally nausea occurred. Loose stool Day 1 ~ 2, the tongue is dark red with white and slightly dry fur, characterized by disorder of liver and spleen and stagnation of blood stasis and toxin, and the method of invigorating spleen and benefiting qi, nourishing liver and detoxifying is adopted. Prescription: ① The prescription is the same as before. ② Decoction: Radix Astragali 30g, Radix Codonopsis 15g, Rhizoma Atractylodis Macrocephalae 15g, Poria 12g, Radix Rehmanniae 15g, Radix Angelicae Sinensis 15g, Radix Ophiopogonis 12g, Fructus Schisandrae 6g, and Zhuru/kloc-2g.

Press: After taking the medicine, the drug of promoting blood circulation and removing blood stasis was reused, and the weight increased, the mass was reduced to 3.0cm×7.0cm×3.0cm, and the thickness of spleen was 3.8cm. The symptoms improved completely and it is still under treatment.

Example 7 Pang Mou, male, 63 years old, from Guangdong. 1June, 997 18 First time to see a doctor. Before 10, the patient was diagnosed as primary liver cancer (massive type) in a hospital in Guangdong, because a mass was felt in the right upper abdomen. Masses of 7.0cm×5.8cm and 3.5cm×4.4cm were found in the right lobe, and huge masses of 10.4cm×7.2cm were found in the left lobe, accompanied by gallbladder enlargement and cholecystitis. The hospital thinks that the treatment is meaningless, and the survival time is about 3 months, or even shorter. The patient was introduced by a friend of the patient and sought medical advice. Symptoms: Abdominal distension, abdominal circumference 103cm, B-ultrasound showing ascites volume of about 7000ml, weight of 56kg, abdominal distension and oliguria, acute pain in the liver area, yellow eye and sclera, yellow color, anorexia, loose stool, thick and greasy tongue coating and thready pulse. Usually, she likes to drink hard liquor. For about 3 A Liang days, four fingers are under the ribs of the liver, five fingers are under the xiphoid process and four fingers are under the ribs of the spleen. Syndrome differentiation and classification: wine hot and wine wet hurts the liver and spleen, liver qi stagnates, and it turns into heat for a long time, spleen and stomach stagnate, and water and blood stasis are intertwined. Treatment: clearing away heat and promoting diuresis, invigorating spleen and promoting diuresis, clearing liver and dredging collaterals, softening and resolving hard mass. Prescription: ① Codonopsis pilosula 10g, Atractylodes macrocephala 10g, Pericarpium Citri Tangerinae 10g, Poria cocos 30g, Radix Paeoniae Rubra 24g, Papaya 10g, Achyranthes bidentata 10g, Pericarpium Arecae 10g, Pangolin/kloc. ② Take Cidan Capsule 10 box, 40 bottles of Kang, 40 bottles of Fuzheng Guben Capsule 10 box and 40 bottles of Shuangbai Pills as a course of treatment.

The second diagnosis (July of the same year 17): After taking the medicine, the sputum volume increased greatly, the abdominal distension became flat, the abdominal circumference was 87cm, and the jaundice was exhausted, with two fingers under the liver rib, three fingers under the sword and two fingers under the spleen rib. Recently, due to exogenous factors, my throat is swollen and sore, my voice is hoarse, my cough is less and sticky, and my throat is red and swollen. Quasi-pre-method plus clearing product. Prescription: ① Chinese patent medicine is the same as before. ② Cortex Moutan 10g, Fructus Forsythiae 15g, Scutellariae Radix 6g, Radix Clematidis 10g, Bombyx Batryticatus 10g, Radix Paeoniae Rubra 12g, Lasiosphaera Pubescentis 10g, Poria 15g. After taking the medicine, ascites disappeared. The sore throat has been removed and the appetite has been fragrant. If all the symptoms disappear, they are still under treatment and observation.

Example 8 Hongmou, male, 55 years old. On February 6, 2006, the patient was diagnosed as primary liver cancer in Hong Kong 1996-65438+ by CT examination and pathological examination, accompanied by a large amount of ascites and portal vein tumor thrombus, and could not be operated and chemotherapy. 65438+February 10, through Xiamen's family, I came to mail-order Cidan capsules and (Kang). After four courses of treatment, ascites miraculously subsided and the effect was excellent. Life expectancy is 2 months, but it has been greatly exceeded so far, which is called "miracle" by western medicine. On July 1997, 1, the patient visited our hospital in person. CT showed that the right liver tumor was 6cm×2cm×3cm, cholecystitis was accompanied by multiple stones, the spleen was huge, the spleen occupied a substantial space, and the left kidney moved down. There was no other discomfort except dull pain in the liver area, pain in the back and waist, yellow tongue coating and rapid pulse. Prescription: Cidan Capsule, Compound Rhizoma Curcumae Xiaoliu Capsule, Zhengxiaokuai (Zhengtongkang), Fuzheng Guben Capsule and Ganhong (Sanyuan) Zhushui Pill. After taking the above drugs for half a course of treatment, all the symptoms disappeared, and people who are normal are still actively being treated.

Case 9 Huang, male, 54 years old, first diagnosed in May, 1996. Because of bloating after drinking, CT and MRI showed that the left liver tumor was about 12cm× 1 1cm. Interventional chemotherapy was done in mid-April, and no good effect was found. Symptoms: dull pain in the liver area, aversion to oil, anorexia, spontaneous sweating and dry mouth. Loose stool, 4-5 times a day, lethargy, moist tongue coating, thick sublingual collaterals and slippery pulse. Syndrome: spleen should not be sparse, and phlegm stagnates. Treatment: invigorating the spleen and soothing the liver, and removing blood stasis. Prescription: ① Zheng Xiaokang 30 bottles, Cidan Capsule 10 box, Fuzheng Guben Capsule 10 box, 4 times a day. Take a course of treatment. ② Radix Codonopsis 20g, Radix Astragali 25g, Rhizoma Atractylodis 12g, Pericarpium Citri Reticulatae Viride 10g, Herba Scutellariae Barbatae 30g, Poria 30g, Fructus Aurantii 10g, Radix Salviae Miltiorrhizae 10g, Radix Curcumae 10g, Fructus Crataegi 30g, Caulis Spatholobi 30g and Rhizoma Dioscoreae 30g.

The pain disappears after taking the medicine, and it will be fragrant after 2-3 days. According to the above syndrome, it was increased or decreased to 1997, the liver function was normal, AFP was less than 20μ g/L, and the strong echo mass in the left liver was 6.8cm×7.2cm by B-ultrasound, which was much smaller than before. Today's diagnosis: I gained a little weight, the pain in the liver area disappeared, and I occasionally felt sick and pooped. The patented medicine is still on the prescription. The decoction reduces Radix Curcumae and Pericarpium Citri Reticulatae Viride, and adds Pericarpium Citri Reticulatae10g and Caulis Bambusae10g.

1997. 7. 5 The patient had no obvious chief complaint, and the third reexamination showed that the left lobe of the liver was 3.0cm×5.3cm echo mass, and everything else was normal. Still according to the original method, the Chinese patent medicine Cidan Capsule, Zheng Xiaoyu (Kang) and Fuzheng Guben were used.

Press: The blood supply of the liver mainly comes from hepatic arterial system and portal vein. After embolization, the blood flow of hepatic artery decreased by 90% ~ 95%, and the normal liver parenchyma also decreased by 35%, so liver parenchyma damage or liver failure may occur. At present, patients who are involved in chemotherapy are treated with traditional Chinese medicines such as promoting blood circulation, nourishing yin, protecting liver and expelling toxin. Restore the viscera function and qi and blood function of the body, comprehensively enhance the immune ability of the body, improve the anti-cancer function, and prolong the life of patients.

Case 10: Li, male, 33 years old, was first diagnosed on1June/July, 997. On June 1 day, the patient was diagnosed with abdominal distension in the Affiliated Hospital of Guangdong College of Traditional Chinese Medicine (No.28897): liver cancer after liver cirrhosis, splenomegaly, a small amount of ascites, and the mass size was about 5cm×4cm. After treatment in the same hospital, CT scan was performed on June 13, and the mass has increased to 1 1cm×20cm, with cirrhosis, splenomegaly and a small amount of ascites. Symptoms: purple and yellow body, slippery pulse. This is the accumulation of damp heat, stagnation of liver qi, imbalance of middle energizer and viscera failure. Treatment: dispel damp-heat, regulate qi, regulate middle energizer and benefit viscera. Prescription: ① Zheng Xiao Pill (Zheng Tongkang) 40 bottles, 4 times a day,1g; Every time; 40 bottles of Chenyin Shuangbai Pills, 4 times a day,1g; Every time; Cidan Capsule and Compound Zedoary Curcuma Xiaoliu Capsule 10 box, 4 times a day, 5 capsules each time. ② Herba Artemisiae Scopariae 30g, Caulis Saussureae Involucrata 30g, Herba Hedyotidis Diffusae 30g, Folium Isatidis 30g, Rhizoma Smilacis Glabrae 30g, Radix Isatidis 30g, Radix et Rhizoma Rhei 6g, Radix Salviae Miltiorrhizae 10g, Radix Curcumae 10g, Fructus Crataegi 30g, Fructus Citri Sarcodactylis 10g, and pericarpium Arecae 30g.

The second diagnosis (July of the same year 17): After taking the medicine, jaundice subsided, the remaining symptoms were greatly alleviated, the tongue coating was thin and white, and the pulse condition was full. Re-examination: the mass was 7cm×8.3cm, and no ascites was found. Still the above method, I didn't take Chinese patent medicine for a course of treatment, and I took Chinese medicine decoction in a reduced amount. It is still under active treatment.