The patents of generic drugs have not yet expired, and the poor cannot afford the medicines. How high are the R&D costs for pharmaceutical companies?

Do you still remember the movie "I'm Not the God of Medicine"? The main plot of this scene is that Lu Yiyi and others must smuggle generic drugs that can get the same effect from India because they cannot afford the high price of the original research drugs. These people can survive thanks to the generic medicines smuggled back from India by the protagonist Cheng Yong, who is regarded as the "God of Medicine".

What are original investigational drugs and generic drugs? The so-called original research drugs are original innovative drugs discovered and used clinically for the first time in the world. Typically, its patent protection period is 20 years. Original investigational drugs are original new drugs that are approved for marketing only after tens of thousands of compounds have been screened and rigorous clinical trials have been conducted. It takes about 15 years of research and development and huge funding.

Usually, only large multinational pharmaceutical companies can develop. The marketing of original investigational drugs usually involves a series of processes, such as project approval, preclinical studies, clinical study application, clinical trial approval, clinical studies, production application, post-acceptance notification review and site inspection, and approval of the drug. Production and sales monitoring period. This is also the reason why genuine drugs are called "expensive drugs". The cost invested during this period will take a certain amount of time to be recovered. When the patent on the original investigational drug expires, other pharmaceutical companies can conduct research on generic versions of the drug.

Drugs produced in this way are called generic drugs, and their active ingredients, administration methods and indications are the same as the original drugs. So what are generic drugs? Generic drugs are generic drugs that are identical or similar to the original drug in terms of dosage, safety and efficacy, quality, effectiveness and indications. The effect is almost the same, but the price is very different. But the quality of generic drugs can vary. What is the difference between original investigational drugs and generic drugs? ?

1 Original investigational drugs cost more than gold and may not be affordable for many people. Generic drugs are much cheaper and closer to people. 2. The efficacy of the two is similar, and the original drug is better. 3. In terms of adverse reactions, there are fewer original research drugs. Most of the initial investigational drugs were developed by large multinational companies, and their production technology, pharmaceutical excipients and tablet crushing technology were more scientific and rigorous. So, should I choose brand-name or generic drugs?

1. If financial conditions permit, choose original drugs; 2. If the economy cannot afford it, then having generic drugs is a good thing. After all, choosing a generic drug is important to cure the disease and protect your life. A moment of thought: Even though original investigational drugs are expensive, they still need to be encouraged and protected. Otherwise, big pharmaceutical companies will lose the incentive to develop new drugs and will become a setback for society. Generic drugs provide more life opportunities to ordinary people and the law should also be considered to a certain extent. Hope tomorrow will be better and better!