Why does drinking beer induce hyperuricemia and gout? Is the purine content of wine high?

Although the purine content in alcohol is not high, it cannot be ignored. First, let's not talk about liquor. For example, there are a lot of purines in rice wine and beer. Yellow rice wine contains the most purine. If you drink too much, it will inevitably lead to an increase in uric acid; There are also many purines in beer, and there are not many purines in liquor and beer, but it is not recommended to drink more. It is not only purine in wine but also alcohol (ethanol) that will cause adverse reactions to patients with hyperuricemia and gout. In addition, the unfavorable factors brought by long-term drinking may also aggravate the condition of patients with hyperuricemia gout.

Beer is a drink that many people often drink in their lives. The reason is that beer is light, and many people, especially boys, think it is no different from drinking fruit juice, so they usually drink a lot of beer. Although the degree of beer is very low and the purine content is not particularly high, if you drink too much, it may lead to excessive purine and alcohol, which is definitely not good for patients with high uric acid/gout.

The key is, how does alcohol affect blood uric acid?

Alcohol can produce substances related to uric acid and decompose them, leading to the increase of uric acid;

Alcohol can also affect the purine synthesis substrate in the body to increase it, further increasing the purine synthesis amount and the final metabolic uric acid amount;

In addition, drinking alcohol will not only increase blood uric acid, but also have a bad influence on many organs of the body, especially the liver.

After alcohol enters the body, the first step will be dehydrogenation to produce toxic acetaldehyde. Acetaldehyde can only be discharged from human body if it is dehydrogenated again to produce nontoxic acetic acid. If acetaldehyde accumulates continuously in the body, it will harm liver cells and cause harm to various organs of the body. Therefore, the liver must regard alcohol as VIP and give priority. The process of alcohol decomposition consumes a lot of liver resources and also needs a lot of water and oxygen. If excessive intake leads to insufficient nutrient supply of liver cells, it will also damage liver cells.