What are the causes of nipple discharge?

If there is nipple water during non-pregnancy or lactation, or there is water after squeezing the nipple by hand, it often indicates that there is some kind of disease in the breast. In particular, nipple bleeding water is generally considered as an early manifestation of breast cancer. In fact, although nipple water may have breast cancer, most of them belong to benign breast diseases. According to statistics, breast cancer with nipple discharge accounts for about 13% ~ 7%, and breast cancer with nipple discharge as the first symptom is below 1%. Therefore, nipple discharge is not a "patent" for breast cancer, but we must be highly vigilant and not treat it lightly.

Nipple discharge is mostly related to the high level of prolactin secreted by pituitary gland, so nipple discharge is a "barometer" of prolactin level in vivo. There are two main cases of prolactin increase: one is that the pituitary gland itself has a tumor, and the other is that the nerve center dysfunction makes prolactin inhibitory factor produce too little or stop secreting. For example, mental patients who commonly use chlorpromazine, hypertensive patients who take reserpine, patients who often take motilium stomach disease, insomnia patients who often take diazepam, oral contraceptives and anti-tuberculosis drugs. Their blood prolactin levels increased significantly, leading to nipple discharge. In addition, hypothyroidism, hemophilia, thrombocytopenic purpura, renal insufficiency, bronchial cancer, diabetes, breast trauma, breast inflammation and so on. It can also cause nipple discharge.